Posted by admin on Aug 31, 2022 in |
Triumfetta rhomboidea, often known as diamond burbark or Chinese bur, is a member of the Tiliaceae family. The plant is known as a weed, but a number of medicinal properties have been reported for its different parts. It is a tropical and subtropical shrub that can be found in India, Ceylon, the Malay Peninsula, China, Africa, and America. According to phytochemical analysis, it contains carbohydrate glycosides, phytosterol, steroids, flavonoids, tannin & phenolic compounds, and triterpenoids, which can be associated with various pharmacological properties such as antioxidant, antimicrobial, antitumor, antibacterial, diuretic, anti-diabetic, antiproliferative, anti-inflammatory, antitubercular, anthelmintic and lactogenic properties. This review mainly focuses on the traditional uses of various plant parts, phytochemical constituents and reported pharmacological...
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Posted by admin on Jul 31, 2022 in |
Worldwide antimicrobial resistance is a serious problem and differs from region to region. This study has designed the determination of the incidence and sensitivity pattern of Escherichia coli (E. coli) and discusses the general issues related to antimicrobial resistance. Prospective study was carried out between JAN to April 2020. Samples of urine, blood, pus and miscellaneous (fluids, swabs and sputum) were collected from indoor patients. The present antimicrobial susceptibility of E. coli, the study was performed in the Department of Microbiology Narayana Super-specialty Gurugram, Total of 315 samples were tested out, 97 samples showed growth on culture and out of 97 samples, 40 E. coli have isolated and tested antibiotics sensitivity, it has been demonstrated that different samples showing a significant amount of antimicrobials Sensitivity and resistance to different antibiotics (Table 2). Antimicrobials, namely Meropenem have shown sensitivity (65%), imipenem (60%), Colistin (70%). Thus, there is a need for the implementation of strong antimicrobial stewardship program and stop misuse of antibiotics with an instant effect. Our region’s present study...
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Posted by admin on Jul 31, 2022 in |
Iron deficiency anaemia afflicts a large proportion of the human population, compromising productivity and quality of life. Iron supplements are widely prescribed for treating anaemia. However, poor compliance due to side effects, particularly gastrointestinal side effects, remain a hurdle in alleviating the problem, leading to unabated high prevalence. Thus, a fresh look at novel approaches to supplementation is essential. Iron toxicity is attributed to the Fenton Reaction and generation of reactive oxygen species leading to oxidative stress. Several studies suggest that the FR and ROS caused by excess iron, results in chronic inflammation, leading to metabolic syndrome, diabetes mellitus, atherosclerosis, cancer, neurodegenerative disorders. Iron chelates have been developed as treatment modalities to reduce free radical generation, reduce GI side effects, and enhance absorption. Classical Fe chelators, developed to counteract iron overload/ toxicity, cannot be used in IDA, due to severe side effects. In Ayurveda, iron formulations are prepared using phytomolecules that chelate iron and/or reduce OS. These phytomolecules are metabolized by the gut microbiota, which plays an important role...
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Posted by admin on Jul 31, 2022 in |
This study was carried out to investigate the antibacterial and antifungal potentials of Abies webbiana and Berberis aristate Linn. The study aims to assess the antimicrobial activity and determine the zone of inhibition of extracts on some bacterial and fungal strains. The extracts determined the antimicrobial activity using the agar disc diffusion method. The antibacterial and antifungal activities of extracts (5, 25, 50, 100, 250 μg/ml, and so on) of A. webbiana and B. aristata were tested against different Gram-positive and Gram-negative bacteria and four fungal strains: Aspergillus niger, Candida albicans, and Penicillium notatum and Penicillium funiculus. The zone of inhibition of extracts was compared with that of a standard like ciprofloxacin for antibacterial activity and griseofulvin for antifungal activity. The results showed that the remarkable inhibition of the bacterial as well as fungal growth was shown against the tested organisms. The phytochemical analyses of the plant extracts indicated the presence of saponins, tannins, alkaloids, flavonoids, triterpenoids, steroids, glycosides, anthraquinones, coumarin, saponins, gum, protein, and amino acids. The antimicrobial...
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Posted by admin on Jul 31, 2022 in |
Natural products with medicinal value are becoming increasingly important in food preservation. Tinospora cordifolia, a plant commonly known as Guduchi, is highly beneficial in the medicinal field and has been used for centuries to treat various diseases. Due to the discovery of active components in Tinospora species and their potential for disease control, this plant has gained interest across the globe. Various pharmacological characteristics such as antioxidant, hepatoprotective, neuroprotective, antidiabetic and analgesic antitumor activities support its medicinal properties making it a promising herb with various health benefits. These biological activities of Tinospora species can be attributed due to the presence of a wide range of phytoconstituents, including alkaloids, flavonoids, lignans, Furano diterpene glucosides and sterols. The clinical importance of Tinospora cordifolia is included in this review to investigate its potential uses as an ingredient for the food industry. The future scope of the review remains in exploiting and isolating antimicrobial compounds to enable new and effective formulations in food...
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