Posted by admin on Apr 30, 2020 in |
Predisposing exposures to cadmium have been implicated in hepatotoxicity, hence the search for therapeutic interventions. Thirty Wistar rats were randomly grouped into six (1-6) with 5 rats each. Group 1 received only 5mg/kg body weight (b.wt) of Cadmium Chloride (CdCl2) intra-peritoneally. Group 2 received feed and water ad libitum. Groups 3 and 4 received CdCl2 followed by low and high dose (10mg/kg b.wt and 40mg/kg b.wt respectively) of Aqueous Extract of the Zest of Citrus sinensis (AEZCs). Groups 5 and 6 were pre-treated with low and high doses of the extract before CdCl2. Extract administrations were orally and the experiment lasted for 8weeks. The livers were harvested, grossed and the liver to Bodyweight ratios (LW/BW) was determined shortly before being processed for histology and homogenate for SOD and MDA assay. Blood samples were collected for AST, ALT, ALP and total proteins (TP) analysis. Significant (p<0.05) differences in LW/BW, SOD, MDA, ALT, ALP, AST and TP were observed between groups 1 and 2. This was similarly noted between groups pre-treated...
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Posted by admin on Mar 31, 2020 in |
The study aimed at checking the effects of aqueous extracts of Vernonia amygdalina and Ocimum gratissimum on the electrolyte level of salt-loaded rats. 25 male rats weighing 160-220g were shared into 5 groups of 5 rats. Group 1 animals that were fed standard feed and water served as the control. Animals in group 2-5 which were salt-loaded orally with 2 ml of 4% sodium chloride solution for 2 weeks, were left untreated, treated with 1 ml of 300 mg/kg body weight of aqueous bitter leaf extract, 300 mg/kg body weight of aqueous extract of scent leaf and 300 mg/kg body weight of both extracts in ratio 1:1 respectively. Treatment of salt-loaded animals with the extract was done orally once daily for two weeks after which plasma electrolyte levels were determined. There was significant (P<0.05) increase in Na+ and Cl− levels in all the salt-loaded groups when compared with the control group. Bitter leaf extracts significantly (P<0.05) decreased the sodium level only when compared to the group with no treatment...
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Posted by admin on Feb 29, 2020 in |
A major challenge in treating bacterial infections is the increasing incidence of microbial resistance to antibiotics. This poses a serious threat prompting the search for alternative strategies to treat bacterial infections. Metal nanoparticles as novel antibiotic agents hold promise because they show strong antibacterial activity against various bacterial species, including Gram-positive and Gram-negative bacteria. Green synthesis of nanoparticles offers minimization of wastage, reduction of derivatives, use of non-toxic solvent, auxiliaries and renewable feedstock. A single step, an eco- friendly, cost-effective method is used for the synthesis of copper nanoparticles (CuNPs) from 1.0 mM copper sulphate solution using extract of Ocimum sanctum (Tulsi) leaves as reducing and capping agent. UV-VIS, FESEM, FTIR and XRD were used to confirm and characterize the NPs. The biosynthesized copper NPs were phased pure and well crystalline with a simple cubic structure. Antibacterial study of the biogenic CuNPs suggests their efficacy against common human bacterial pathogen species. Gram-negative test organisms were found to be more susceptible to toxicity of biosynthesized CuNPs. Metal nanoparticles hold the...
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Posted by admin on Dec 31, 2019 in |
A bird is often subjected to dysbacteriosis with a low quality of feed. As a result, live weight gain and livability are reduced in broilers. This problem has become particularly acute now when most countries have abandoned the use of feed antibiotics. Significant assistance in this situation is provided by new regulators of intestinal biosynthesis – probiotics. In our research, we used biosporin produced by the Military and Technical Problems Centre of the Research Institute of Microbiology of the Russian Ministry of Defense. Scientific and household experience was conducted on the basis of ZAO “Ural broiler”. Three groups were formed: one control group and two experimental ones. There were 100 units in each group. The results of scientific and household experience lead to the conclusion that biostim is more preferable with the comparative use of two liquid probiotic products from the point of view of production figures. Feeding it to a bird in accordance with the instruction allows increasing the live weight of broiler chickens by 11.5%, reducing the...
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Posted by admin on Sep 30, 2019 in |
This study was aimed to investigate the effects of different levels of dietary chromium picolinate (CrPic) on performance, some blood biochemical and intestinal morphology and microflora in Ross 308 broiler chicks. A total of 240 broiler chickens Ross 308 strain, from 21 to 42 days old were used in a completely randomized design. All chickens consumed a diet based on the corn-soybean meal, and the treatments were control- (thermo-neutral) and control + (heat stress) with no add-on and the others with CrPic supplementation at levels 500, 1000 and 1500 ppb respectively. The blood serum samples were subjected to biochemical analysis for blood parameters. The histomorphometric examination was performed by light microscopy. The result showed that all the growth and feed intake and feed conversion ratio parameters were declined when the broilers fed the CrPic supplementation (P≤0.05). The serum glucose concentration decreased CrPic supplemented groups. As a result, revealed that the villus height and crypt depth in the ileum and jejunum. Ileal villus height of birds on CrPic groups was...
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