Posted by admin on Sep 30, 2019 in |
This study was aimed to investigate the effects of different levels of dietary chromium picolinate (CrPic) on performance, some blood biochemical and intestinal morphology and microflora in Ross 308 broiler chicks. A total of 240 broiler chickens Ross 308 strain, from 21 to 42 days old were used in a completely randomized design. All chickens consumed a diet based on the corn-soybean meal, and the treatments were control- (thermo-neutral) and control + (heat stress) with no add-on and the others with CrPic supplementation at levels 500, 1000 and 1500 ppb respectively. The blood serum samples were subjected to biochemical analysis for blood parameters. The histomorphometric examination was performed by light microscopy. The result showed that all the growth and feed intake and feed conversion ratio parameters were declined when the broilers fed the CrPic supplementation (P≤0.05). The serum glucose concentration decreased CrPic supplemented groups. As a result, revealed that the villus height and crypt depth in the ileum and jejunum. Ileal villus height of birds on CrPic groups was...
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Posted by admin on Aug 31, 2019 in |
The present investigation aims to evaluate the effect of methanol extract of Spatoglossum asperum for its anti-hyperglycemic activity against diabetics induced by alloxan in Wistar albino rats. Artificially diabetes was induced in albino rats by the administration through injection of a single dose of alloxan monohydrate (10 mg/kg, I.P). The 10 mg/kg methanol residue of S. asperum was administered as a single oral dose per day to diabetes-induced rats for 28 days. The outcome of algae residue feeding was estimated by various biochemical and hematological parameters such as RBC, WBC, Hb, and platelets and lipid profile. After feeding of algal methanol extract of S. asperum in diabetic rats for 28 days, the blood glucose had significantly decreased, whereas the liver glycogen level had increased. Histopathological examination of the pancreas was done. The methanol residues of the Spatoglossum asperum possess very effective anti-hyperglycemic activity on the diabetic rats as compared to...
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Posted by admin on Jul 31, 2019 in |
Ethanol extracts of rambutan leaves have been investigated for their anti-diabetes properties using the glucose tolerance method as well as insulin deficiency through alloxan induction. This study aimed to further evaluate these properties in obese and insulin resistant animals. The rat models were feeding with foods high in carbohydrates, fats, and propylthiouracil. The animal models were divided into seven groups: normal group, the positive control group, rambutan leaf extract at doses of 17.5, 35, and 70 mg/kg b.w., and the orlistat and metformin groups. The parameters evaluated during therapy were body weight, food index, feces index, and blood glucose levels. The rambutan leaf ethanol extract at a dose of 17.5 mg/kg b.w. resulted in a decrease in body weight by 2.44% compared to the initial body weight and could also decrease appetite with the amount of food intake equal to 10.71 g compared with the positive test group at 12.49 g. The rats administered 35 mg/kg b.w. rambutan leaf ethanol extract excreted 6.29g of feces and exhibited a decreased...
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Posted by admin on Jul 31, 2019 in |
The present research work was considered to achieve preliminary phytochemical screening, acute oral toxicity, antioxidant activity, and to evaluate the antihyperlipidemic property of the aqueous and ethanolic extracts of leaves of Amaranthus tricolor. Antioxidant activities of the aqueous and ethanolic extracts of leaves of Amaranthus tricolor were investigated by Free Radical Scavenging Activity (DPPH method) and antihyperlipidemic activity by in-vivo effects on an atherogenic diet (2% cholesterol, 1% choline chloride and 2% Lard) induced rats hyperlipidemia. Our results exposed that Amaranthus tricolor showed potent antioxidant properties. In the cholesterol-induced hyperlipidemic model, groups of rats treated with extracts A. tricolor showed a significant reduction in total cholesterol (TC), triglycerides (TG) and in levels of SGOT, SGPT, ALP, LDH, and CKMB activities whereas increase in the level of high-density lipoprotein (HDL) compared to cholesterol-induced hyperlipidemic control group at dose-dependent manner but the effect was less than the standard drug Atorvastatin. It was observed from the histopathological findings that rats fed with A. tricolor extracts showed a decrease in granular degeneration caused...
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Posted by admin on Jun 30, 2019 in |
To assess the effect of Perillyl alcohol (POH) on the lipid profile of high-fat-diet-induced hyperlipidemia in white male albino Wistar rats, the hyperlipidemia was induced by feeding cholesterol-rich high-fat diet for 45 days in male albino Wistar rats. The decline in the triglycerides, LDL and VLDL was significant at 100 & 200 mg/kg dose of POH compared to Atorvastatin group. The decrease in total cholesterol was significant at 100 and 200 mg/kg doses compared to hyperlipidemic control. The results demonstrate that POH at a dose of 100 and 200 mg/kg body weight lowers the serum triglyceride, LDL, VLDL, total cholesterol and increase HDL level significantly in high-fat-diet-induced hyperlipidemic rats. Though there was no significant effect on the lipid profile at 50 mg/kg dose. Thus, the results of the present study provide scientific validation for the use of Perillyl alcohol (POH) a terpene as an Antihyperlipidemic...
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