Posted by admin on Dec 31, 2024 in |
Parasitic worms live in and feed in living hosts. They receive nourishment and protection while disrupting their hosts ability to absorb nutrients. The macroparasites called helminths, causes Helminthiasis. In India, the overall prevalence rates range from 12.5% to 66%. About 50% of the urban population and 68% of the rural population in India is affected. According to WHO, just few medications are consistently utilized for the treatment of these parasite diseases, these include albendazole, mebendazole, piperazine thiabendazole and levamisole. The resistance of helminths to drugs poses health complications to both man and animals which increased the demand for the use of herbal drugs. The present study was carried out to evaluate anthelmintic activity of leaves of Trachyspermum ammi and Desmodium gangeticum. Earthworms (Eisenia fetida) were chosen for studying anthelmintic activity as they have resemblance to intestinal round worms. The earthworms were exposed to series of concentrations 100mg/ml, 200mg/ml, 300mg/ml, 500mg/ml, 1000mg/ml of leaf extracts. Albendazole is used as a standard drug. Results revealed that a dose dependent decrease of paralysis time and death...
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Posted by admin on Jul 31, 2024 in |
Biochar can be used as an efficient and low-cost adsorbent for wastewater treatment as heavy metal pollution has become the serious issue for environmental pollution today. A number of studies have demonstrated effective removal of heavy metals from water by biochar. Several factors affecting the sorption tendency of biochar, feedstocks materials play a significant role. Depending on the biochar type, heavy metals can be removed by different methods such as complexation, physical sorption, precipitation and electrostatic interactions. In recent years, ample method for heavy metal removal from wastewater has been extensively studied. This paper reviews the recent methods that have been used to treat heavy metal removal from wastewater and evaluates these techniques. These techniques include ion-exchange capacity, adsorption, membrane filtration, coagulation-flocculation, flotation and electrochemical methods. From literature review it is evident that ion-exchange, adsorption and membrane filtration are the most recent studied for the treatment of heavy metal...
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Posted by admin on Sep 30, 2023 in |
Background: Post-marketing surveillance via spontaneous Adverse drug reaction (ADR) monitoring and reporting method is in place, even though it is considered as one of the key challenge for under-reporting and establishing the quality of patient safety in the healthcare system. Objective: This study is intended to know the clinician’s opinion (mindset) on the implementation of PvPI-Helpline (Helpline Number) and concise ADR form in In-patient case sheets at a tertiary care teaching hospital, Telangana India as they play a vital role for improving the reporting system of ADRs. Materials and Methods: A Cross-sectional Surveillance based study was carried out in Osmania medical college and affiliated hospitals, for 2-months duration among 160 Clinicians. The questionnaire consists of 4 questions and the participants were informed to provide their feedback. Data was collected and analyzed using SPSS version 25 software. Results: Only150 clinicians responded. 98.6% of Clinicians agreed to implement PvPI-Helpline (Toll-Free) number for quick reporting of ADRs.93.3% disagreed with creating a WhatsApp group for reporting ADRs as they taught it was not a secure platform to...
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Posted by admin on May 31, 2023 in |
Central and eastern Brazil is home to the cactus species Cereus jamacaru, also called mandacaru or cardeiro. It frequently reaches a height of 6 metres. For animal feed, a kind without thorns is utilized. The most typical type is quite thorny; however, if the thorns are The native Brazilian cactus Cereus jamacaru D.C., also known as “mandacaru,” grows naturally in the Caatinga biome and is characterized as a source of food and medicines used to cure kidney inflammation, urinary infection, and rheumatism. However, the antioxidant activity and phenolic chemicals have not yet been assessed. The current study’s phytochemical examination of the ethanolic extract to assess the phytochemical, antioxidant, and anti-diabetic effects of C. jamacaru root extracts showed the Presence of terpenoids and flavonoids, saponins, alkaloids, steroids, coumarin and carbohydrates. This study has demonstrated that C. jamacaru root extract contains primary and secondary metabolites that can be pharmacologically useful and possess some antidiabetic and antioxidant properties. It was also discovered that C. jamacaru root ethanol extract possessed antioxidant and antidiabetic...
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Posted by admin on Apr 30, 2023 in |
Enzymes are biocatalysts that accelerate biotic reactions positively or negatively. Proteases are small types of enzymes that cleave peptide bonds. These proteases can be produced by microbes (fungi, bacteria, and viruses), plants, and animals. The catalytic site is only visible from the outside and is broadly dispersed on the surfaces of different cell types. Based on the position of the cleavage site in the putative substrate, these peptidases can be classified as endopeptidases or exopeptidases. These peptidases are used in a variety of industries, including laundry detergents, leather and fabric processing, food processing, baking, flesh tenderization, food additives, artificial sweetener synthesis, feed, cheese making and the dairy industry, soy sauce production, brewing and cereal processing, photography, environmental bioremediation, medical and pharmaceutical industries, plant pathology, nitrogen production, and so on. Proteases are classified based on physiological roles. Extracellular proteases breakdown down large proteins into smaller parts on the other hand, intracellular proteases helps in the regulation of...
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