Posted by admin on Mar 31, 2025 in |
The utility of herbal medicines incresed for curative purposes in the past few years. They serve as a curative alternative for a significant section of the worldwide community. Nonetheless, assessing the reliability of such facilities continues to be challenging in guaranteeing their safe use. Acute and subacute toxicity studies were conducted in a rat model. The cytotoxicity assay and AO/PI staining of HALEPR was carried out in an endometrial cell. Acute toxicity was evaluated in female Charles Foster rats over 14 days, revealing no mortality or severe adverse effects, suggesting a Lethal Dose 50 (LD50) above 2000 mg/kg. Subacute toxicity was assessed over 28 days with no significant changes (P < 0.05) in body weight, feed consumption, water intake, or biochemical parameters. Histological examination of organ tissues indicated no notable differences between treated and control groups. The antiproliferative activity of HALEPR was investigated using primary endometrial cell cultures. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay demonstrated a significant apoptotic effect with an IC50 of 41.46 µg/mL. This result was further confirmed...
Read More
Posted by admin on Jan 31, 2025 in |
Psychrozymes, a diverse set of cold-active enzymes produced by psychrophiles including β-galactosidases, pectinases, and amylases which are examined for their specific benefits across various food processing domains. An in-depth exploration of psychrophiles in cold fermentation processes reveals their pivotal role in shaping the sensory attributes of fermented foods and beverages. Psychrophiles contribute to nuanced flavour profiles and distinctive textures, positioning them as catalysts for innovation in cold fermentation. Psychrophiles in bio-preservation have led to advancements in cold-chain technologies, which extend the shelf life of refrigerated and frozen foods while minimizing energy consumption, providing sustainable solutions. This paper highlights food biotechnological applications, showcasing psychrophiles role in advancing brewing and bioconversion of agricultural byproducts, their influence in baking, flavouring, meat tenderization, cheese production, and animal feed formulation. Additionally, this paper also deals with the mechanism and factors contributing to survival of psychrophiles in cold temperatures. Psychrophiles transcend traditional boundaries, impacting sensory attributes and nutritional profiles across a variety of food...
Read More
Posted by admin on Jan 31, 2025 in |
An evergreen semiparasitic plant belonging to the Loranthaceae family, Dendrophthoe falcata (L.f.) Ettingsh is common throughout India and feeds on a variety of host species. The potential of silver nanoparticles (AgNPs) produced by D. falcata-mediated processes is still unknown, despite the known bioactivity of D. falcata extracts. The present investigation examines the phytochemical profile of leaf extracts from D. falcata, their function in the synthesis of AgNPs, and the AgNPs’ bioactivity. The existence of tannins, terpenoids, alkaloids, and flavonoids was verified by phytochemical analysis. AgNPs were synthesized and characterized using UV-Vis spectrophotometry, FTIR, SEM, TEM, and XRD, confirming their structural integrity and stability. The DPPH radical scavenging assay revealed AgNPs’ robust antioxidant properties by showing that their capacity increased proportionately with incubation time and that their purple coloring significantly decreased. Also, AgNPs proved robust antibacterial activity, comparable to positive controls against E. coli, a gram-negative bacterium. They showed a notable inhibition zone against gram-positive bacteria at a 300 μl concentration. Further, AgNPs inhibited S. aureus, albeit only at higher...
Read More
Posted by admin on Dec 31, 2024 in |
Parasitic worms live in and feed in living hosts. They receive nourishment and protection while disrupting their hosts ability to absorb nutrients. The macroparasites called helminths, causes Helminthiasis. In India, the overall prevalence rates range from 12.5% to 66%. About 50% of the urban population and 68% of the rural population in India is affected. According to WHO, just few medications are consistently utilized for the treatment of these parasite diseases, these include albendazole, mebendazole, piperazine thiabendazole and levamisole. The resistance of helminths to drugs poses health complications to both man and animals which increased the demand for the use of herbal drugs. The present study was carried out to evaluate anthelmintic activity of leaves of Trachyspermum ammi and Desmodium gangeticum. Earthworms (Eisenia fetida) were chosen for studying anthelmintic activity as they have resemblance to intestinal round worms. The earthworms were exposed to series of concentrations 100mg/ml, 200mg/ml, 300mg/ml, 500mg/ml, 1000mg/ml of leaf extracts. Albendazole is used as a standard drug. Results revealed that a dose dependent decrease of paralysis time and death...
Read More
Posted by admin on Jul 31, 2024 in |
Biochar can be used as an efficient and low-cost adsorbent for wastewater treatment as heavy metal pollution has become the serious issue for environmental pollution today. A number of studies have demonstrated effective removal of heavy metals from water by biochar. Several factors affecting the sorption tendency of biochar, feedstocks materials play a significant role. Depending on the biochar type, heavy metals can be removed by different methods such as complexation, physical sorption, precipitation and electrostatic interactions. In recent years, ample method for heavy metal removal from wastewater has been extensively studied. This paper reviews the recent methods that have been used to treat heavy metal removal from wastewater and evaluates these techniques. These techniques include ion-exchange capacity, adsorption, membrane filtration, coagulation-flocculation, flotation and electrochemical methods. From literature review it is evident that ion-exchange, adsorption and membrane filtration are the most recent studied for the treatment of heavy metal...
Read More
