Posted by admin on Jul 31, 2022 in |
Pectinase is a collection of enzymes that degrade pectin into simpler compounds known as galacturonic acids. Microbes and plants largely produce pectinase, and it has a wide range of biotechnological applications in food, agriculture, industry, the environment and medicine. Fruit juices, coffee, cocoa, tea, jams and jellies are all made with pectinase in the food industry. Furthermore, pectinase, a supplemental enzyme found in animal feed, increases nutrient absorption. Pectinase has been utilized in the agricultural sector for plant virus purification, oil extraction, retting and degumming processes, and cotton fiber bio-scouring. They play a critical function in wastewater treatment by facilitating pectin breakdown in the environmental sector. Pectinases are mostly used in the wine and paper industries in the industrial sector. Pectinases are probiotic enzymes that are introduced to a variety of foods in medicine. This review aims to compile all of the accessible information on pectinase enzymes’ biotechnological applications in diverse...
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Posted by admin on Jul 31, 2022 in |
Any errors in medical dispensing may threaten the patient’s life. Hence, this research aimed to compare and evaluate the dispensing errors and to identify its prevalence and severity through the safety reporting system (SRS) and providing feedback at “King Abdulaziz Medical City, Central Region (KAMC-CR)” and “King Abdullah Specialized Children’s Hospital (KASCH)”.The KAMC-SRS was used to collect data on dispensing errors. In order to analyze the dispensing errors, the reasons for the errors were reviewed and the errors were classified. In order to study and categorize the medication error data, the “National Coordinating Council for Medication Error Reporting and Prevention (NCCMERP)” index was utilized. Out of 3017 safety reports submitted to the SRS during 2017, the number of dispensing errors recorded was 448 (14.84% of the errors). Out of 2381 safety reports submitted to the SRS in 2018, approximately 18% of dispensing errors were recorded, which were significant (p < 0.001). Generally, “KAMC and KASCH” pharmacies showed relatively low percentages of dispensing errors that did not exceed 0.01% of...
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Posted by admin on May 31, 2022 in |
Ulcerative colitis was defined as a common intestinal infla-mmatory disease characterized by upregulation of pro-inflammatory cytokines and oxidative stress. The leaves of Murraya koenigii and Centella asiatica had been used in traditional medicine to treat the disease. The present study aimed to perform a comparative protective efficacy evaluation between Murraya koenigii and Centella asiatica on acetic acid-induced ulcerative colitis in rats. Rats were randomly categorized into nine groups: control, acetic acid, standard drug, acetic acid + extract of Murraya koenigii (50, 100, 200 mg/kg), and acetic acid + extract of Centella asiatica (50, 100, 200 mg/kg) groups. After 5 days of feeding, colitis was induced in the experimental animal groups by transrectal administration of 1ml of 4% acetic acid. The rats were sacrificed after 24 hr of rectal installation, and their colon tissues were examined. Pretreatment with extract of Murraya koenigii and Centella asiatica significantly reduced colon weight-length, macroscopic scores, histological changes, and upregulated the enzymatic activity of superoxide dismutase (SOD). The above results indicated that oral administration of...
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Posted by admin on May 31, 2022 in |
Urochloa distachya (Poaceae), commonly known as Signal grass 20-60 cm long found in tropical Asian origin, Africa, and other countries. Generally, it has been used in fodder, animal feed etc., and least and no therapeutic activities were reported. The present study was established to identify the phytochemicals by using GC-MS of the U. distachya leaves part. The leaves part of the plant was extracted in methanol by using the Soxhlet apparatus. The GC-MS Methanolic extract of U. distachya identified 26 phytocomponents; Z-7-Pentadecenol; t-Butyl hydrogen phthalate, Ricinoleic acid; Methyl -12-hydroxy-9-octadecenoate; Octadecanoic acid; Glycerin; 4, 6-Diphenyl-2-(2-hydroxyphenyl) pyrimidine, Eicosanoid acid, methyl ester, 2-Naphthalenol 2, 3, 4, 4a, 5, 6, 7-octahydro1, 4adimethyl-7-(2-hydroxy-1-methylethyl); Cholest-5-en-3-ol (3á), tetradecanoate; 6-Octadecenoic Acid; Oleic acid, 3-hydroxypropyl ester; Octadecanoic acid, 2, 3-dihydroxypropyl ester; Eicosane; Tert-Hexadecanethiol; 2-[4-methyl-6-(2, 6, 6-trimethylcyclohex-1-enyl) hexa-1, 3, 5-trienyl] cyclohex1en-1-carboxaldehyde; Spiro [4.5] decan-7-one, 1, 8-dimethyl-8, 9-epoxy-4-isopropyl; 9, 12, 15-Octadecatrienoic acid, 2, 3-bis [(trimethylsilyl) oxy] propyl ester, (Z, Z, Z). The phytoconstituents of methanolic extract of U. distachya has shown remarkable activities like antimicrobial, antioxidant, anti-inflammatory and anticancer...
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Posted by admin on Mar 31, 2022 in |
Copper is an essential trace element involved in a plethora of functions being a component of several enzymes. Copper deficiency affects people of all age groups, including infants, children, pregnant women, and men. Deficiency occurs due to numerous factors hindering the absorption/uptake of copper. Male Wistar rats (35-50 gm) were divided into four groups: Group 1: Negative control – fed with standard feed (Ashirwad Industries, Chandigarh) and tap water was provided ad libitum .Group 2: Copper control group- Fed with diet containing 126 nmol Cu/gm. Tap water was provided ad libitum. (c) Group 3: Pair-fed group – Fed with 126 nmol Cu /gm diet but the amount of feed given was equal to the feed consumed by the copper-deficient group the previous day to account for stress and starvation effect caused due to low intake diet. Tap water was provided ad libitum (d) Group 4: Copper deficient- animals were fed with 6.3 nmol Cu / gm diet, and demineralized water was provided ad libitum. The experiment was conducted for...
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