1.
Controlling the crystal growth in a crystallization set up is a complex and time taking process. In the domain of pharmaceutical set up, crystal differences will largely affect the drug performance and stability. Therefore, it is essential to control the crystallization process and optimize the experimental set up to get desired particle characteristics. Process Analytical Technology (PAT) tools a...
Jamshed Haneef * and Mohd Danish Khan
Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, Delhi, New Delhi, India.
DOI: 10.13040/IJPSR.0975-8232.16(6).1465-79
1465-1479
2.
Computer-aided drug design programs use mathematical formulas to predict the property value and structure of stable, unknown, and molecular species. Quantum mechanics, hybrid QM/MM, molecular bonding, molecular modelling, molecular mechanics, and QSAR are some of the techniques used in molecular bonding studies. An average drug discovery cycle, from lead identification to clinical trials, is expec...
Radhe Govind Sahu, Shiv Hardenia * and Dinesh Kumar Jain
IPS Academy College of Pharmacy, Knowledge Village, Rajendra Nagar, A.B. Road Indore, Madhya Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.16(6).1480-93
1480-1493
3.
Hernia repair is one of the most common surgeries, with recent advancements in mesh technology and surgical techniques significantly improving outcomes. Mesh implants are the standard for reinforcing abdominal walls, reducing recurrence rates compared to traditional sutures. However, complications like chronic pain, infection, and adhesions have driven innovations in mesh development. Modern synth...
S. Rajesh, R. Akash, S. Deepa * and K. Sathesh Kumar
Department of Pharmaceutical Chemistry, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.16(6).1494-18
1494-1518
4.
Chromosomal non-disjunction is a pivotal error in cell division where chromosomes fall to separate properly during meiosis or mitosis, resulting in an abnormal number of chromosomes, the condition is known as aneuploidy. This phenomenon has significant consequences for human health, as it underpins several kinds of genetic disease, such as Downsyndrome, Turner syndrome and Klinefelter syndrome. No...
Ayshwarya Purkait, Durgamadhab Das, Goureesh Ghosh, Khokan Bera, Souvik Kundu * and Rahul Patra
Department of Pharmaceutical Science and Technology, Seacom Pharmacy College, Dhulagori, Howrah, Jala Dhulagiri, West Bengal, India.
DOI: 10.13040/IJPSR.0975-8232.16(6).1519-31
1519-1531
5.
Hypertension (HTN), a major global health concern and the primary cause of cardiovascular disease (CVD) death is expected to impact 29% of all adults by 2025. Hypertension (HTN) is a multifactorial condition, arising from the complex interaction of hereditary, environmental, and physiological variables that contribute to elevated systolic and diastolic blood pressure. It is frequently caused by dy...
A. Samyuktha, Arya Arun Kumar, Saraswathi Saraswathi *, Ashok Dayalan and Jagadisha Tavarekere Venkataravanappa
Department of Life Sciences, Kristu Jayanti College Autonomous, Bangalore North University, Bengaluru, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.16(6).1532-40
1532-1540
