1.
Parkinson’s disease is the second most common progressive, age-linked neurodegenerative disorder. The sporadic form of the disease is usually idiopathic, where mitochondrial dysfunction is its major hallmark. Mitochondria are multifunctional dynamic organelles that carry out major cellular functions that get damaged by reactive oxygen species, deposition of lewy bodies, dopaminergic neuronal cel...
Saniya Tabassum and Anjali Raj *
Department of Pharmacology, The Oxford college of Pharmacy, Hongasandra, Bangalore, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.13(6).2211-20
2211-2220
2.
As new treatments and medication are growing rapidly, neurologists are also toward expanding treating patients with idiopathic Parkinson's disease and facing questions regarding cannabis as a treatment elective, particularly for levodopa-safe Parkinson's symptoms. Cannabinoids compounds like delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) are the most abundant chemicals present. Whereas T...
Douglas Zorinmawia Chhakchhuak, G. Swetha Saniya Tabassum and Anjali Raj *
Department of Pharmacology, Pharmacy # 6/9, 1st Cross, Begur Road, Hongasandra, Bengaluru, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.13(6).2221-29
2221-2229
3.
Parkinson’s disease (PD), identified as the second most common neurodegenerative disorder, is a progressive disease that impairs the ability to control voluntary movements mainly. According to the findings of the pathogenesis of PD, lesions in dopaminergic innervation of the basal ganglia cause degeneration of neurons in the substantia nigra and thus leads to loss of striatal dopamine level. Hen...
V. G. Kanase *, P. M. Pandagale and S. M. Dani
Department of Pharmacology, Oriental College of Pharmacy, Navi Mumbai, Maharashtra, India.
DOI: 10.13040/IJPSR.0975-8232.13(6).2230-41
2230-2241
4.
Oroxylum indicum (O. indicum), commonly known as the Indian trumpet tree, belonging to the family Bignoniaceae, is a medicinally important, small, or medium-sized plant used to treat various diseases and also has its importance in the traditional system of medicine. Various parts of the plant have been proved to possess useful pharmacological activities. It is native to the Indian subcontinent, ex...
V. G. Kanase *, P. M. Pandagale and S. M. Dani
Department of Pharmacology, Oriental College of Pharmacy, Sanpada, Navi Mumbai, Maharashtra, India.
DOI: 10.13040/IJPSR.0975-8232.13(6).2242-50
2242-2250
5.
At a time where we understand that new drug discovery and development involves significant cost, expensive products and is the slow-paced process, an innovative idea called ‘Drug Repositioning’, which basically means repurposing of old drugs to treat diseases including both common and rare are being increasingly attractive as it provides drug development in a sustainable cost, time efficiently...
Abhilash Poudyal, Barsha Subba and Sonam Bhutia *
Government Pharmacy College Sajong, Government of Sikkim, Sikkim University, Sajong , Sikkim, India.
DOI: 10.13040/IJPSR.0975-8232.13(6).2251-62
2251-2262
