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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Volume 15 (2024) - Issue 7, July

Review Articles

 
Title
Views
PDF
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1.

A REVIEW: DIFFERENT EXTRACTION TECHNIQUES ON PLANT ALKALOIDS

Natural products have achieved approval globally for assisting healthcare and also disease obstruction. Alkaloids are an important group of diversely distributed, chemically, biologically and commercially significant natural product which have various organic compounds that give different pharmacological activities. The most important and initial step in medicinal plant is extraction because the b...

Uplabdhi R. Kohre *, Puja R. Basule, Komal Wahane, Atul T. Hemke and Milind J. Umekar

Department of Pharmaceutical Chemistry, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1870-85

1870-1885

247

255

2.

LOCUST BEAN GUM: A PROMISING MATERIAL IN ORAL DRUG DELIVERY SYSTEM

The increasing demand for natural polymers has fuelled substantial investment in research and development within the pharmaceutical and biotech sectors. Natural polymers, lauded for their biocompatibility, biodegradability, and safety, offer versatile advantages and among these, polysaccharides and proteins stand out. One class of natural polymers, gums, obtained primarily from plants, is gaining ...

Abhradeep Kuiry and Sanjit Kr Roy *

Department of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Haringhata, Nadia, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1886-96

1886-1896

196

101

3.

REVOLUTIONIZING PRODUCTION: THE ASTONISHING POWER OF PELLETS AND PELLETIZING TECHNOLOGY AND THEIR APPLICATION

In today's dynamic industrial landscape, the transformative potential of pellets and pelletizing technology stands as a beacon of innovation. Pellets, compacted forms of raw materials, have emerged as versatile solutions across diverse sectors, from agriculture to pharmaceuticals, offering enhanced efficiency and sustainability. The advent of advanced pelletizing technologies has further elevated ...

Saddam *, Suman, Shripad Motilal Bairagi, Sanket Jangle and Shashi Alok

Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1897-13

1897-1913

189

93

4.

NANOEMULSION: A CARRIER FOR DRUG DELIVERY

Researchers' interest in nanotechnology, and specifically nanoemulsions (NEs), has grown over time. NEs have a significant role in various sectors because of their droplet size is small and large surface area. The components, characteristics, creation, and applications are outlined in this review article. This article also discusses the benefits and drawbacks of nanoemulsion. High input energy and...

Shweta Yadav, Pragya Mishra and Navneet Kumar Verma *

Buddha Institute of Pharmacy, GIDA, Gorakhpur, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1914-28

1914-1928

183

101

5.

REVIEW ON SCOPE AND APPLICATION OF POSTBIOTICS IN FOOD PRESERVATION

Food safety is at risk from several variables, including physical, chemical, and biological risks. In this context, biological risks are of utmost significance. The bacteria among them are crucial in producing food deterioration and food-borne illnesses. Additionally, a novel strategy has been applied in recent years that relies on pro-biotic and post-biotic to inhibit the increase of pathogenic m...

Tamalika Chakraborty *, Zarin Parwez, Nayana Verma, Tushar Gupta, Kaustav Deb and Tamoghna Chakraborty

Guru Nanak Institute of Pharmaceutical Science and Technology, 157/F Nilgunj Road, Sodepur Panihati, Kolkata, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1929-40

1929-1940

199

96

6.

PRONIOSOMAL DRUG DELIVERY SYSTEM- A REVIEW

Proniosomes are provesicular dried or anhydrous formulations that are composed using non-ionic surfactants and solvents. The non-ionic surfactant's hydrophilic portion orients outward to form a bilayer, while the hydrophobic portion moves inward. Medicines with hydrophilic properties are contained in vesicles, while hydrophobic drugs get embedded in proniosome bilayers. Proniosomes are physically ...

K. Bains *, K. Slathia and M. Sharma

Himalayan Institute of Pharmacy, Kala-Amb, Himachal Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1941-50

1941-1950

82

46

7.

MANAGEMENT OF GREEN PHARMACEUTICALS

Green Pharmacy represents a holistic approach to healthcare that emphasizes the importance of controlling the environmental contamination caused by pharmaceuticals. Also, Green Pharmacy prevents environmental contamination due to the API (active pharmaceutical ingredient) present in the medicines. Contamination of the environment by Active pharmaceutical ingredients can occur through various pathw...

Shiraz Mehdi *, Tabrez Uz Zaman and Syed Saif Imam

Department of Hospital Management and Hospice Studies, Jamia Millia Islamia, Jamia Nagar, Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1951-62

1951-1962

83

42

8.

AFFORDABLE ARTIFICIAL INTELLIGENCE TOOLS IN CANCER DIAGNOSIS AND TREATMENT

Numerous genetic and epigenetic differences contribute to the complexity and multifaceted nature of the disease known as cancer. Artificial intelligence is opening up a lot of possibilities in the fight against cancer. AI-guided clinical care has the potential to significantly reduce health problems, particularly in low-resource countries. Numerous tools and applications of AI are being offered in...

Nainci Dhiman and Deepika Sharma *

Department of Biotechnology, Chandigarh Group of Colleges, Landran, Mohali, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1963-70

1963-1970

70

51

9.

CAPPARIS ZEYLANICA LINN: A COMPREHENSIVE REVIEW

Capparis zeylanica Linn (Capparidaceae), commonly known as “wild caper” is a plant species found in tropical regions. It is known as culinary and medicinal uses. The abstract of a comprehensive study on this plant might discuss traditional uses, phyto-chemical composition. Also, future perspectives about plant: is a computational technique used to study the interaction between small molecules,...

Harshada Dupade * and Dhanashri Dupade

Fabtech College of Pharmacy, Sangola, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1971-82

1971-1982

62

32

10.

A REVIEW ON DIABETIC PERIPHERAL NEUROPATHY: PATHOPHYSIOLOGY, DIAGNOSIS AND PHARMACOTHERAPY

Diabetic Peripheral Neuropathy (DPN) is a prevalent and debilitating complication of diabetes mellitus, impacting the global well-being of millions. This review provides a concise overview of the key aspects related to DPN, including its pathophysiology, diagnostic approaches, and current pharmacotherapeutic interventions. The pathophysiology involves intricate mechanisms driven by hyperglycemia-i...

Minol Vijayan * and Praseena Kotheri

Department of Pharmacology, National College of Pharmacy, Manassery, Mukkam, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1983-90

1983-1990

62

34

11.

NAVIGATING THE FUTURE OF MEDICINE: EXPLORING THE LATEST BREAKTHROUGHS IN THE PHARMACEUTICAL INDUSTRY FOR A BRIGHTER TOMORROW

The pharmaceutical industry is undergoing a significant transformation due to technological advancements, scientific breakthroughs and evolving healthcare needs, paving the way for more effective treatments and improved patient outcomes. AI and ML are revolutionizing drug discovery and development by analysing vast datasets, predicting drug interactions and accelerating the identification of poten...

T. Bana, P. Kadu * and P. Pimple

Mrs. Saraswati Wani College of Pharmacy, Ganegaon, Ahmednagar, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).1991-99

1991-1999

88

52

Research Articles

 
Title
Views
PDF
Cited
12.

PRECLINICAL EVALUATION OF HYDROALCOHOLIC EXTRACT OF SIDA SPINOSA FOR ITS ANTI-ARTHRITIC ACTIVITY IN MICE

The present study aimed to evaluate the effect of hydroalcoholic extract of Sida spinosa L. (HYSS) in antigen induced rheumatoid arthritis in mice by intra articular administration of Bovine serum. Rheumatoid arthritis was induced by the mixture of antigen (Bovine serum albumin) and adjuvant (Imject alum) in 1:1 ratio on 1st, 7th and 21st day as an induction period. The mixture of antigen and adju...

G. H. Patil *, A. V. Kulkarni, S. S. Patil and S. B. Kasbe

Department of Pharmacology, Dr. D. Y. Patil College of Pharmacy, Dr. D. Y. Patil Educational Complex, Sector 29, Nigdi Pradhikaran, Akurdi, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2000-06

2000-2006

173

96

13.

ANATOMICAL STUDIES OF ELAEOCARPUS SERRATUS LINN.

The medicinal plant Elaeocarpus serratus Linn., (Elaeocarpaceae) has been utilized in traditional medicine for various ailments. However, upon reviewing the literature, it was found that no anatomical work had been conducted on this plant. Therefore, our present study aimed to determine the macroscopic and microscopic characteristics of fresh leaf and stem of Elaeocarpus serratus. The macroscopic ...

D. H. Geetha * and Indramuthu Jayashree

Department of Botany, Vellalar College for Women, Erode, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2007-16

2007-2016

168

76

14.

IN VITRO ANTIOXIDANT AND IN VIVO IMMUNOMODULATORY STUDY OF LEMON PEEL EXTRACT (STORG-FA) AND ITS BIOAVAILABILITY ASSESSMENT

Background: Natural bioactive compounds of plant origin have attracted comprehensive attention due to their multiple biological effects, including antioxidant and immunomodulatory activities. However, scientific underpinnings of these health benefits are inadequate. Objective: Present investigation was undertaken to evaluate the bioavailability, antioxidant, and Immunomodulatory activity of the he...

H. M. Firoz, C. T. Sadashiva * and A. K. Sreedrisya

R & D Department, Star Hi Herbs Pvt. Ltd, Jigani, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2017-27

2017-2027

173

100

15.

NUTRITIONAL QUALITY UPGRADING OF INDIGENOUSLY DEVELOPED RICE MUTANT THROUGH EXPLORATION OF PHYTIC ACID AND AMYLOSE REGULATORY GENES

Phytic acid and amylose in rice food play an essential role in human health. The best-practiced approach is necessary for nutritional quality improvement of rice grain. The mutational breeding approach and chemical treatment are powerful methods to enhance rice quality by managing the concentration of phytic acid and amylose contents. The analysis of glycemic index and amylose contents is also sig...

Manjoo Rani

Department of Pharmacy, Shri Ram Murti Smarak College of Engineering and Technology Bareilly, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2028-35

2028-2035

161

65

16.

ATTENUATION OF NEPHROTOXICITY INDUCED WITH CISPLATIN IN HEK 293 CELL LINES BY SAGADEVI NEI

Sagadevi nei is a Siddha polyherbal formulation indicated for Neerkattu and Neersurukku. The main ingredient of the formulation is Vernonia cinerea, belonging to the family Fabaceae, which has been proven scientifically to exhibit renal tubular regrowth. Based on Literature, each ingredient of the mixture has nephroprotective, diuretic, antioxidant, and anti-inflammatory properties. Cisplatin is a...

B. Abarna, M. Sathyarathish, V. Manjari * and K. Kalaivanan

Department of Nanju Maruthuvam, National Institute of Siddha, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2036-40

2036-2040

176

73

17.

INHIBITION OF GROWTH OF BRUSHITE CRYSTALS USING KULITTH-YUSH WITH AND WITHOUT CITRIC ACID

The present study examined the potential of horsegram yush/ broth on preventing growth of calcium hydrogen phosphate dihydrate (Brushite) crystals in vitro. Crystal length was measured daily over a period of 11 days Two types of yush were tested (a) akruth yush made with only salt or (b) kruth yush with Trikatu consisting of equal proportions of long pepper (Piper longum), black pepper (Piper nigr...

Shubha Venkateswaran Gulkotwar, Mihir Joshi, Shobha A. Udipi * and Ashok Vaidya

Kasturba Health Society-Medical Research Center, Department of Food Science and Nutrition, SNDT Women’s University, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2041-52

2041-2052

51

26

18.

ETHANOLIC EXTRACTS OF CAESALPINIA BONDUCELLA LEAVES FOR ANTIDIABETIC ACTION IN ALBINO RATS

Further investigation into the mechanisms underlying the antidiabetic and antihyperlipidemic effects of Caesalpinia bonducella leaf extracts is warranted to elucidate its potential as a therapeutic agent for managing metabolic disorders such as hyperglycemia and hyperlipidemia. Future studies could explore the extract's impact on insulin sensitivity, glucose uptake in peripheral tissues, and its i...

Sonam *, Gaurav, Harendar Kumar Nivatya, Nitin Kumar and Suman

Department of Pharmaceutics, Saraswathi College of Pharmacy, N.H. 09, Anwarpur, Hapur, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2053-57

2053-2057

71

32

19.

DIFFERENTIAL SCANNING CALORIMETRY AND INFRARED SPECTROMETRY METHODS FOR THE QUANTIFICATION OF ETHAMBUTOL HYDROCHLORIDE IN ORAL DOSAGE FORMS

A new, simple, and sensitive differential scanning calorimetry and infrared spectrophotometric technique was developed to estimate ethambutol hydrochloride in tablet dosage form. In the first method the concentration range of ethambutol hydrochloride was discovered to be 0.5 mg to 2.0 mg using differential scanning calorimetry (DSC), with the peak region of an exothermic thermogram at 75.8 °C and...

N. Delhiraj * and A. M. Sekar

Department of Pharmaceutical Analysis, School of Pharmacy, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2058-63

2058-2063

60

32

20.

EFFECT OF PARTICLE SIZE ON YIELD OF PLANT EXTRACT

Plant extracts are in use in the form of decoctions and water infusions in Ayurvedic systems of medicine since ancient times.  It is generally believed that particles finer in size, produce more amount of extract yield. However, there appears to be no uniformity in using powders of any particular particle size for extraction. Coarse and fine powders of different particle sizes have been observed ...

S. S. Savrikar *, Unmeshi Sabnis and Mukund Sabnis

Jeevanrekha Analytical Services, Deolai, Aurangabad, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2064-71

2064-2071

69

36

21.

COMPARATIVE STUDY OF LIGNOCAINE SUBTENONS ANESTHESIA VSPERIBULBAR ANESTHESIA IN MANUAL SMALL INCISION CATARACT SURGERY AND PHACOEMULSIFICATION

Aim: Comparison of safety and efficacy in subtenon anesthesia versus peribulbar anesthesia in manual small incision cataract surgery by randomized control trial. Setting and design: A prospective observational study was conducted among 150 patients undergoing MSICS at a tertiary care hospital and was grouped into two groups peribulbar anesthesia and subtenon anesthesia. Material and Method: After ...

M. Immanuel Jebastine *, Surendhar Amargeeth, Reethika Mathansekar, N. Sandhya, G. Nanda Perumal and D. Bhuvaneshwari

Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science Technology & Advanced Studies, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2072-78

2072-2078

78

40

22.

HPTLC FINGERPRINT PROFILE AND STANDARDIZATION OF CYAMOPSIS TETRA-GONOLOBA (L.) TAUB.

Cyamopsis tetragonoloba belongs to the family Fabaceae and has notable medicinal properties as it is used as a digestive aid. Guar Gum, which is a high molecular weight carbohydrate with multiple industrial applications, is also obtained from this plant. Methanolic extracts of C. tetragonoloba were obtained through reflux extraction to perform further experiments. Various experimental tests were c...

Nikhita Mirekar, M. Ananya, Sana Iddalagi, Narayanachar and Vijay Danapur *

Vriksha Vijnan Private Limited, 31/2, SSB Complex, Subramanyapura Main Road Bengaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2079-87

2079-2087

58

27

23.

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION STUDIES FOR SIMULTANEOUS ESTIMATION OF LULICONAZOLE AND EUGENOL USING UV SPECTROSCOPY

A simple, precise yet novel UV spectrophotometric method has been developed for the simultaneous estimation of luliconazole and eugenol. Two methods, namely the simultaneous equation method and the absorbance ratio method were tried for simultaneous analysis. Since the simultaneous equation method gave the best recovery; the simultaneous method was developed for the estimation of both drugs. The w...

N. Nilawar and T. Khan *

Department of Pharmaceutical Chemistry and Quality Assurance, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, University of Mumbai, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2088-93

2088-2093

70

34

24.

EXPLORING PARENTAL SELF-MEDICATION PRACTICES FOR PEDIATRIC CARE: A CROSS-SECTIONAL OBSERVATIONAL STUDY

The escalating use of medications among children presents a global concern, with self-medication by parents increasingly prevalent. This study investigates the prevalence of self-medication practices among parents of children aged 1 to 12. Methods: Over six months, 200 participants who self-medicated their sick children were enrolled. The study, conducted at King Koti District Hospital in Hyderaba...

S. Noor *, K. Fatima, M. S. Ahmed and A. Azeez

Department of Pharmacy Practice, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2094-02

2094-2102

89

40

25.

EXPLORATION AND ELUCIDATION OF THE PHYSICAL PROPERTIES OF HPMC BASED HERBAL TRANSDERMAL PATCHES, DEVELOPED FOR THE TREATMENT OF FUNGAL SKIN INFECTIONS

Fungal infections represent a significant global challenge within the realm of dermatology. The prevalence of fungal infections is notably high, affecting approximately 40 million individuals in developing and underdeveloped countries. Considering this, our study proposes a novel approach: transdermal drug delivery utilizing herbal formulations to enhance efficacy & minimize side effects in th...

B. N. Ramakrishna *, D. M. Surendra and Santhosh C. Siddhashrama

Department of Physics, Government College for women, Mandya, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2103-10

2103-2110

52

26

26.

VARIABILITY IN VENOUS THROMBOEMBOLISM PROPHYLAXIS FOR INPATIENT MEDICAL PATIENTS: A DESCRIPTION OF DIFFERENCES IN PRACTICE ACROSS THE PRAIRIE PROVINCES

Background: Venous thromboembolism is the most common preventable cause of in-hospital mortality. Despite this, thromboprophylaxis practices vary related to order sets and special populations. Aim: To describe thromboprophylaxis strategies and awareness of institutional policies. Methods: Electronic survey of pharmacists having general medicine institutional practices within Alberta, Saskatchewan ...

Tammy J. Bungard *, Darcy A. Lamb, William A. Semchuk, Jennifer Lowerison, Jennifer Bolt and Peter Thomson

Department of Medicine, University of Alberta, Edmonton, Alberta.

DOI: 10.13040/IJPSR.0975-8232.15(7).2111-15

2111-2115

63

39

27.

EVALUATION OF ANTIRETROVIRAL TDDS CONTAINING NATURAL PENETRATION ENHANCER

Aim: This study aims to explore the potential of transdermal drug administration as a viable alternative to conventional medication delivery systems. Specifically, the focus is on the development and evaluation of transdermal patches containing Lamivudine and Stavudine for the treatment of AIDS. The overarching objectives include extending drug release duration, reducing administration frequency, ...

Rajesh Kumar *, Richa Mishra and Manmeet Singh Saluja

Sunrise University, Alwar, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2116-22

2116-2122

60

26

28.

STUDY OF PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITIES OF LIGUSTRUM SINENSE (LOUR.)

More attention on natural antimicrobials and antioxidants have increased. The medicinal plants production has high in Mediterranean region. WHO says many drugs can be obtained by using medicinal plants. Medicinal plants have many compounds of bioactive that gives more metabolic action on the human body. The congestive heart failure treatment and cardiac arrhythmia treatment can be treated by glyco...

M. Shakila Begam *, R. Mouli, P. Akilandeswari and B. V. Pradeep

Department of Microbiology, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2123-31

2123-2131

65

34

29.

A STATISTICAL STUDY OF THE PREVALENCE OF CELIAC DISEASE IN ADULTS IN TWO SYRIAN GOVERNORATES (HOMS- TARTOUS) DURING THE PERIOD OF 2014-2022

Celiac disease is a multisystem immune based disorder that is triggered by the ingestion of gluten in genetically susceptible individuals. Our study was limited to a survey of the prevalence of Celiac disease in adult in two Syrian governorates (Homs and Tartous), Statistics were collected from hospitals and clinics of gastroenterologists and nutritionists, during the period of 2014-2022. 4000 cas...

Hala Hassan Deeb

Al Hawash Private University, Collage of Pharmacy, Syria.

DOI: 10.13040/IJPSR.0975-8232.15(7).2132-37

2132-2137

60

28

30.

ENHANCING SOLUBILITY AND DISSOLUTION OF RESERPINE THROUGH OPTIMIZED SOLID DISPERSION AND FAST- DISSOLVING FILM FORMULATION: A QUALITY BY DESIGN APPROACH

This study aims to enhance the therapeutic effectiveness of reserpine, an essential anti-hypertensive agent, by addressing its poor solubility and dissolution properties. Employing a Quality by Design (QbD) methodology, the research systematically optimized the formulation using solid dispersion technology and fast-dissolving films. Characterization of reserpine included its physical properties, s...

Dupinder Kaur *, Richa Mishra and Manmeet Singh Saluja

Sunrise University, Alwar, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2138-52

2138-2152

67

41

31.

ETHNO-GYNECOLOGICAL KNOWLEDGE OF MEDICINAL PLANTS USED BY RURAL PEOPLE OF VILLAGES OF GURUGRAM DISTRICT, HARYANA INDIA

Ethnogynaecology is a young field of study that emphasize how indigenous people and local healers manage gynecological conditions in females. The goal of the current study was to record in-depth information about Ethnogynaecology in a previously unexplored region of Haryana. In the year 2022, a floristic and ethnomedicinal survey was conducted in Haryana, India in rural areas of Gurugram district....

Priya * and Manoj Kumar

Department of Botany, Baba Mastnath University, Rohtak, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2153-60

2153-2160

71

33

32.

EXPLORING THE ANTI-INFLAMMATORY ACTIVITY OF FORMULATED AZADIRACHTA INDICA (NEEM) LOADED MICROSPONGES GEL

This research investigates the anti-inflammatory potential of Azadirachta indica-loaded microsponges gel, presenting a novel therapeutic approach. The microsponges gel, formulated with Azadirachta indica, aim to enhance drug delivery efficiency for improved anti-inflammatory effects. The microsponges gel is formulated using Carbopol 934P (1% w/v) to optimized encapsulated microsponge. Prepared for...

Priyanka Vitthal Jadhav * and S. Rajasekaran

Department of Pharmaceutics, Bhagwant University, Sikar Rd, Ajmer, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2161-66

2161-2166

63

33

33.

IN-VITRO ANTIBACTERIAL ACTIVITY OF ARQE AJEEB ON ENTEROCOCCUS HIRAE, ESCHERICHIA COLI, PSEUDOMONAS AERUGINOSA, AND STREPTOCOCCUS MUTANS

The increased use of antibiotics and the rise of antibiotic resistance among microorganisms pose significant public health concerns. While several herbal drugs have been validated for their antimicrobial activity, identification of additional antimicrobial agents is necessary. The Unani system of medicine comprises numerous herbs and formulations used for treating various infections. Arq e Ajeeb (...

S. Nagaraj *, S. N. Basar, L. Banu and N. Sultana

Department of Mahiyatul Amraz (Pathology), Government Unani Medical College Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2167-71

2167-2171

51

27

34.

BAY 11-7085 ANDSU-6656 ATTENUATES ALCOHOL DEPENDENCE INDUCED SPONTANEOUS WITHDRAWAL SYNDROME LIKE HYPERALGESIA, CONVULSION AND DEPRESSION IN MICE

The present study has been designed to investigate the effect of SU6656, a selective inhibitor of src kinase and BAY 11-7085, a selective nuclear factor kappa B inhibitor, as potential target in a mouse model of spontaneous alcohol dependence induced withdrawal syndrome. Our experimental protocol consisted of administration of Alcohol (2 g/kg, 10%, v/v, oral), once daily for 7 days. Assessment of ...

Ajeet Pal Singh *, Ashish Kumar Sharma and Thakur Gurjeet Singh

Nims Institute of Pharmacy, Nims University, Jaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2172-82

2172-2182

52

22

35.

A STABILITY-INDICATING HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF SELINEXOR AND BORTEZOMIB IN BULK AND PHARMACEUTICAL DOSAGE FORM

Symmetric peak and effective peak resolution in chromatography were achieved by adjusting the mobile phase's pH and amount of organic Phase. The retention time of 2.127 and 4.145 minutes was observed after the elution of Bortezomib and Selinexor respectively. To accurately measure both Selinexor and Bortezomib at the same time, an approach was developed with an optimal wavelength of 236nm. Selinex...

Bavita Gaur *, Sandeep Sahu and Mohan Lal Kori

Faculty of Pharmacy, RKDF University, Bhopal, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(7).2183-90

2183-2190

53

30