Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 5.2 | 2.73 | 0.64 |
SIMULTANEOUS DETERMINATION OF PREDNISOLONE AND ASPIRIN IN SYNTHETIC MIXTURE BY VIERORDT´s METHOD
Prednisolone (10mg/day) plus low dose Aspirin (80mg/day) improve the implantation rate in women with autoimmune condition who are undergoing in-vitro fertilization. A new, simple, precise, accurate, and validated simultaneous equation method (Vierordt´s Method) has been developed for simultaneous determination of Prednisolone and Aspirin in the synthetic mixture. The method was based on the measu...
1766
1035
DESIGN AND DEVELOPMENT OF A NOVEL GASTRORETENTIVE MULTIUNIT PARTICULATE SYSTEM AND COLON TARGETED TABLET IN CAPSULE SYSTEM FOR EFFECTIVE MANAGEMENT OF ANAEMIA
Malnutrition is a condition in which there is an imbalance in the proportion of essential nutrients that the body requires to stay healthy. The most prevalent form of malnutrition is micronutrient deficiency and of this iron deficiency anaemia is the most common type, affecting over 2 billion people worldwide. Micronutrients are a special class of vital ingredients that are required in minuscule q...
1911
1651
A SUCCESSFUL ATTEMPT TO ENHANCE SOLUBILITY OF BCS CLASS II DRUG USING LIQUISOLID COMPACT TECHNIQUE
The main purpose of the current research work is to enhance solubility and dissolution of BCS Class II drug, Flurbiprofen using liquid-solid compact technology. Flurbiprofen is a non-steroidal anti-inflammatory drug indicated for acute and chronic treatment of rheumatoid arthritis, osteoarthritis, and spondylytis. The rationale to select Flurbiprofen as the model drug is that it belongs to BCS Cla...
2414
1158
SYNTHESIS AND CHARACTERIZATION OF NANOPARTICLES OF FERROUS SULFIDE BY TWO DIFFERENT STARTING MATERIALS IN THE PRESENCE OF IONIC LIQUID-CAPPING AGENT
Room temperature ionic liquids (RTILs), a class of green and neoteric solvents, have attracted increasing interest over recent years as environmentally benign excellent alternatives to organic solvents in homogeneous and biphasic processes synthesis of several nanoparticles. A novel magnetically recoverable ionic liquid (1,1–Bis(3-Methylimidazolium-1-yl)methanechloride)-stabilized ferrous sulfid...
1520
746
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPTLC METHOD FOR THE ESTIMATION OF SOFOSBUVIR
A simple stability-indicating high-performance thin-layer chromatographic method which is economic, selective, and precise for analysis of Sofosbuvir (SFB), both as a bulk drug and in formulations, was developed and validated according to ICH guidelines. The method employed HPTLC precoated Merck TLC plates RP-18 F254 as the stationary phase while the solvent system prepared by mixing n-Hexane: Eth...
1800
688
BIOCATALYSIS OF DIFFERENT NITRILES TO VALUABLE ACIDS
The biotransformation of different nitrile compounds into valuable acids was attempted using whole cells of nitrile hydrolyzing enzyme produced from a bacteria strain (BITSN007) isolated from sludge sample of Hot spring Surajkund, Jharkhand. Based on the biochemical characterization, the isolate producing nitrilase is predicted as Bacillus sp. The nitrilase production was observed as intracellular...
1543
752
ROLE OF DEOXYCHOLIC ACID IN MODULATING HUMORAL AND CELL MEDIATED IMMUNE SYSTEM
Deoxycholic acid (DCA) is a secondary bile salt that is a major active constituent of Chinese traditional medicine, “Niuhuang” which is known to have immunoregulatory and anti-inflammatory properties. Although data from the literature indicate possible immunomodulatory effects of Deoxycholic acid on the immune system, little has been reported regarding the mode of activity of DCA in modulating...
1607
763
ANTIHYPERGLYCAEMIC AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF CAPPARIS DECIDUA (FORSSK.) EDGEW. IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
The present study evaluates the antihyperglycaemic and antioxidant activity of the methanolic extract of Capparis decidua (CDMtE) fruits in streptozotocin (STZ) induced diabetic rats. Streptozotocin (50mg/kg body weight/) was injected intraperitoneally in rats to induce diabetes. The STZ-induced diabetic rats were treated with CDMtE (200 mg/kg body weight /day) for seven days. Biochemical analysis...
1614
738
EVALUATION OF ANTIDEPRESSANT ACTIVITY OF CHENOPODIUM ALBUM EXTRACTS AND FRACTIONS IN MICE
Traditional systems of medicine emphasize the importance of life-style, including dietary habits, for maintaining holistic health. Ayurveda recommends the use of fruits and vegetables in our diet for maintaining mental health. Chenopodium album is one such popular green vegetable. This plant is rich in phenolic compounds – compounds that are valued for their antioxidant activity and potential fo...
1722
774
AN EFFICIENT AND LABORATORY FRIENDLY SYNTHESIS OF ANTI-GLAUCOMA AGENT OF BIMATOPROST
An alternative, economically viable, and laboratory-friendly synthetic method described for the preparation of Bimatoprost, an anti-glaucoma drug. Stereospecific synthesis of Bimatoprost has been achieved with commercially available (-) Corey lactone i.e., diol, as a starting material. To our delight, the replacement of the benzoyl (Bz) group with Tetrahydropyranyl ether (Thp) protection resulted ...
1964
1119