Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
A SIMPLE UV SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF FEBUXOSTAT IN BULK AND PHARMACEUTICAL FORMULATIONS
A simple and cost effective spectrophotometric method is described for the determination of febuxostat in pure form and in pharmaceutical formulations. The drug was highly soluble in methanol so it was selected as the solvent system for the drug. This ensured adequate drug solubility and maximum assay sensitivity. The linearity range for febuxostat at its wavelength of detection of 315 nm was obta...
6268
1982
POLY-GLUTAMIC ACID (PGA) – STRUCTURE, SYNTHESIS, GENOMIC ORGANIZATION AND ITS APPLICATION: A REVIEW
Mankind has been exploring many new dimensions and techniques to obtain the most feasible and cost effective biopolymers. Biopolymers are the 21st century polymers and are in great demand as they are very easy to produce through the microbial partners and their conglomeration. Future is all about the emancipation of higher finesse quality products with an iota of eco-friendliness. Biodegradation a...
20204
3656
RUBIA CORDIFOLIA – A REVIEW ON PHARMACONOSY AND PHYTOCHEMISTRY
Herbs & its formulations have a long history of use in the treatment of human diseases. Herbal extracts have long been regarded as a source of new and useful pharmaceuticals. According to Cragg's investigation, approximately 62 % of commercially available drugs have natural product origins. Manjistha, or Rubia Cordifolia to give it its scientific name, is a branched climber with small, green...
30232
4375
AN OVERVIEW ON VARIOUS MODIFICATIONS OF CHITOSAN AND IT’S APPLICATIONS
Chitosan is a natural polysaccharide which is widely exploited for its various applications. It has received much attention as a functional biopolymer especially in pharmaceutics and medicine because of its better biodegradability, biocompatibility, versatility and availability. The unique biological applications of chitosan are attributed to these specific properties. The chemical and biological ...
11208
2493
CHALCONE AS A VERSATILE MOIETY FOR DIVERSE PHARMACOLOGICAL ACTIVITIES
Chalcones are 1, 3-diphenyl-2-propene-1-one, consist of two aromatic rings linked by a three carbon α, β-unsaturated carbonyl system. The chemistry of chalcones has generated intensive scientific studies throughout the world. Especially interest has been focused on the synthesis and biodynamic activities of chalcones. These are considered to be precursors of flavonoids and isoflavonoids. The aim...
5190
2961
KINETICS OF ACETYLCHOLINESTERASE INHIBITION BY AN AQUEOUS EXTRACT OF WITHANIA SOMNIFERA ROOTS
Withania somnifera L. Dunal (Family: Solanaceae) is extensively used in traditional Indian medicine as a nerve tonic and is thought to improve memory. We assessed the acetylcholinesterase (AChE) inhibitory activity and kinetics of an aqueous extract of W. somnifera root, in the context of its potential role in regulating the levels of acetylcholine (ACh) in the brain. The assessment of cholinester...
3861
1249
ASSESSMENT OF CYTOTOXICITY AND ANTIBACTERIAL ACTIVITIES OF ETHANOLIC EXTRACTS OF KALANCHOE PINNATA LINN. (FAMILY: CRASSULACEAE) LEAVES AND STEMS
Objective: In the present work, the leaves and stems of Kalanchoe pinnata Linn. (Family: Crassulaceae) have been investigated for screening phytochemicals, cytotoxicity and antibacterial activities. Materials and methods: Brine shrimp lethality (BSL) bioassay was used as a pre-screening method for cytotoxic effect. Ethanolic extract of the plant was tested by using this method. The agar disc di...
3691
1263
PHYTOCHEMICAL ANALYSIS, TOXICITY AND ANTIBACTERIAL ACTIVITY OF BENIN MEDICINAL PLANTS EXTRACTS USED IN THE TREATMENT OF SEXUALLY TRANSMITTED INFECTIONS ASSOCIATED WITH HIV/AIDS
Phytochemical screening of thirteen medicinal plants used in the treatment of sexually transmitted infections (STI), HIV/AIDS in Benin, showed that mucilage, gallic tannins and anthocyanins were the most common chemical groups. Water-ethanol (HE): 4/6 v/v, aqueous (A) and dichloromethane (DCM) extracts were prepared for each plant and tested for toxicity against shrimp larvae (Artemia salina Leach...
4064
1852
ROLE OF THE PHARMACEUTICAL CARE IN THE MANAGEMENT OF PATIENTS WITH TYPE 2 DIABETES MELLITUS
Objective: The study was designed to evaluate the efficiency of pharmaceutical care on the control of clinical parameters, such as fasting glycaemia and glycosylated haemoglobin also to assess drug therapy problems in patients with type 2 diabetes mellitus. Setting: the study was conducted at Diabetic Center in Sulaimany/Iraq, during 18 September 2010 -20 January 2011. Methods: A prospective an...
5514
1590
A COMPARATIVE STUDY OF THE ANTIOXIDANT, ANTIMICROBIAL AND THROMBOLYTIC ACTIVITY OF THE BARK AND LEAVES OF LANNEA COROMANDELICA (ANACARDIACEAE)
The present study was designed to compare the antioxidant, antimicrobial and thrombolytic effects of the Lannea coromandelica bark and leave extracts. After the initial phytochemical screening, the ethanolic fractions of the L. coromandelica bark and leaves were partitioned by solvents of different polarity. Methods used to evaluate the antioxidant potential of the extracts were total phenolic con...
6387
1258