ESTIMATION OF FLAVONOID, PHENOL CONTENT AND ANTIOXIDANT POTENTIAL OF INDIAN SCREW TREE (HELICTERES ISORA L.)
Helicteres isora (L.), a South-Asian plant, is a rich source of medicinal and antioxidant compounds and has been widely used in traditional medicine. Antioxidants are important to neutralize damaging free radicals in the body, especially when the systemic defence mechanisms prove insufficient. The objective of this study was to determine the antioxidant potential of its fresh and dry plant parts i...
An accurate, precise, specific and rapid RP-HPLC method was developed and subsequently validated for the determination of Dapagliflogin in API. Better separation of the drug was achieved on BDS column (250×4.5mm, 5µ) with a mobile phase consisting of a mixture of ortho phosphoric acid and acetonitrile (45:55 v/v) at a flow rate of 1ml/min, with detection at 245nm using Photo Diode Array (PDA) de...
The plant Tephrosia purpurea L. is commonly known as Unhali. T. purpurea (Leguminosae) is a copiously branched perennial herb. Present work was undertaken to study antioxidant potential of the plant. Dried ethanol and aqueous extracts plant were screened for in-vitro antioxidant activity by DPPH assay and nitric oxide screening methods. Results showed that IC50 value of aqueous extract in DPPH ass...
ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF PEELS, PULPS AND SEED KERNELS OF THREE COMMON MANGO (MANGIFERA INDICAL L.) VARIETIES IN SRI LANKA
Mango products are well demanded by consumers due to their unique flavor and mango pulps are developed as various products while mango peels and seeds are the major agro-industrial wastes in canned fruit manufacture and fruit juice processing. Hence the aim of the present study was to investigate on their bioactive phenolic compounds in mango byproducts. Extracts of pulps, seed kernels and peels w...
Medicinal herbs used in modern medicine are occupying a very significant place as raw materials for important drugs. India officially recognizes over 3000 plants for their medicinal value. It is generally estimated that over 6000 plants in India are used in traditional, folk and herbal medicine. Traditionally Ixora is found to be useful for many ailments like hepatic disorder, cancer, microbial in...
Dillenia Indica, commonly known as elephant apple and locally known as outenga, is the handsome evergreen tree grows in the moist forest of sub-Himalayan region to Assam. The fruit grows in abundance and due to lack of knowledge and technical knowledge; most of these fruits are wasted. In Assam, traditionally the unripe fruits are used to make curries because of its sour taste and ripe fruits are ...
SYNTHESIS, SPECTROSCOPIC, THERMAL STUDIES AND BIOLOGICAL ACTIVITY OF A NEW SULFAMETHOXAZOLE SCHIFF BASE AND ITS COPPER COMPLEXES
A new Sulfamethoxazole Schiff base (E)-4-(4-methoxybenzylideneamino)-N-(5-methylis-oxazol-3-yl) benzenesulfonamide (C18H17N3O4S), and its copper complex were synthesized and the structures elucidated on the basis of Physiochemical methods. The studies indicate an octahedral structure for the complexes with the (C22H27N3O10SCu) formula. The IR spectra suggest that the ligand act as tridentate (from...
The aim of this research wok is to formulate and evaluate Ciprofloxacin solid dispersions system by using the different techniques. This will increase the solubility of the drug or Ciprofloxacin and give the immediate release of the drug from the formulations. The main objective is to formulate a drug product as immediate release oral solid dosage form of Ciprofloxacin solid dispersion system whic...
Nootropic drugs used as a memory enhancer can improve thinking, memory, and alertness in people with Alzheimer’s disease andother disease that affect the mind. Memory is perhaps the most vital of all aspects that differentiates human beings from other animals. However, memory can become faulty due to several reasons, and in that case the person is not able to make full use of his or her potentia...
PRELIMINARY PHYSICO-PHYTOCHEMICAL STUDY OF STEM BARK OF ALSTONIA SCHOLARIS (L.) R. BR. – A MEDICINAL PLANT
Alstonia scholaris (L.) R. Br. is a plant of family Apocynaceae and has a great medicinal importance. It is widely used by tribal people to treat various diseases and ailments. The present communication deals with the organoleptic and preliminary physico-phytochemical studies of the stem bark of the plant. The organoleptic study was done according to the W.H.O. guidelines for medicinal plants. The...