Dillenia Indica, commonly known as elephant apple and locally known as outenga, is the handsome evergreen tree grows in the moist forest of sub-Himalayan region to Assam. The fruit grows in abundance and due to lack of knowledge and technical knowledge; most of these fruits are wasted. In Assam, traditionally the unripe fruits are used to make curries because of its sour taste and ripe fruits are ...
ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC EFFECTS OF DIFFERENT FRACTIONS OF STEVIA REBAUDIANA LEAVES IN ALLOXAN INDUCED DIABETIC RATS
The present study carried out to investigate the antihyperglycemic, oral glucose tolerance test (OGTT) and antihyperlipidemic (Total cholesterol and triglycerides) effects of the different fractions (Petroleum ether, ethyl acetate and chloroform) of ethanolic extract of Stevia rebaudiana leaves. The different fractions of the extract were administered orally as a single dose of 150 mg/kg body weig...
SYNTHESIS, SPECTROSCOPIC, THERMAL STUDIES AND BIOLOGICAL ACTIVITY OF A NEW SULFAMETHOXAZOLE SCHIFF BASE AND ITS COPPER COMPLEXES
A new Sulfamethoxazole Schiff base (E)-4-(4-methoxybenzylideneamino)-N-(5-methylis-oxazol-3-yl) benzenesulfonamide (C18H17N3O4S), and its copper complex were synthesized and the structures elucidated on the basis of Physiochemical methods. The studies indicate an octahedral structure for the complexes with the (C22H27N3O10SCu) formula. The IR spectra suggest that the ligand act as tridentate (from...
Natural pigments have great interest with in the market now a day’s particularly microbial pigments. The various microorganisms such as Micrococcus, Bacillus, Rhodotorula, Monascus, Phaffia, Sarcina and Achromobacter have the capability to produce different pigments. These colors have number of beneficial properties like anti-cancerous, immunosuppressive, antibiotic, anti-proliferative, bio-degr...
A COMPARATIVE STUDY OF THE ANTIOXIDANT, ANTIMICROBIAL AND THROMBOLYTIC ACTIVITY OF THE BARK AND LEAVES OF LANNEA COROMANDELICA (ANACARDIACEAE)
The present study was designed to compare the antioxidant, antimicrobial and thrombolytic effects of the Lannea coromandelica bark and leave extracts. After the initial phytochemical screening, the ethanolic fractions of the L. coromandelica bark and leaves were partitioned by solvents of different polarity. Methods used to evaluate the antioxidant potential of the extracts were total phenolic con...
Periodontitis is a common and widespread disease, which occurs due to the pathogenic bacterial infections (like Porphyromonas gingivalis, Bacteroides spp., E. coli, Staphylococcus aureus, S. mutans etc.) established within the gingival sulcus. This condition, when not arrested, will cause formation of periodontal pocket. In order to eliminate or control the disease and arrest further periodontal t...
More than 50% of pharmaceutical products are orally administered for several Reasons and undesirable taste is one of the important formulation problems that is Encountered with such oral products. Taste of a pharmaceutical product is an important parameter governing compliance. Hence taste masking of oral Pharmaceuticals has become important tool to improve patient compliance and the Quality of tr...
The poor dissolution rate of water-insoluble drugs is still a major problem conforming the pharmaceutical industry. The most common method for improving the solubility is by increasing the surface area of the drug through micronization. But, in practice the effect of micronization is often disappointing, especially when the drugs are encapsulated or tablet. It is generally recognized that low solu...
ANTIDIABETIC, ANTIHYPERLIPIDAEMIC AND ANTIOXIDANT ACTIVITY OF WATTAKAKA VOLUBILIS (L. F) STAPF LEAVES IN ALLOXAN INDUCED DIABETIC RATS
The ethanol extract of Wattakaka volubilis (L. f) Stapf. (Family: Asclepiadaceae) leaf was investigated for its antidiabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg, i.p). The ethanol extract of Wattakaka volubilis at a dose of 150mg/kg of body weight was administered at single dose per day to diabetes induced rats for a ...
BIOCHEMICAL AND ANTIMICROBIAL STUDY OF BOERHAVIA ERECTA AND CHROMOLAENA ODORATA (L.) KING & ROBINSON
Purpose: The present study was designed to evaluate the phytochemical, biochemical and antimicrobial activity of leaf extracts of Boerhavia erecta and Chromolaena odorata. Methods: The leaves of Boerhavia erecta and Chromolaena odorata were washed with tap water followed by distilled water. The cleaned leaves were shade dried and then made to fine powder by using homogenizer. Ab...