ANALYSIS OF BIOACTIVE CONSTITUENTS FROM THE LEAVES OF MALLOTUS TETRACOCCUS (ROXB.) KURZ, BY GAS CHROMATOGRAPHY – MASS SPECTROMETRY
Mallotus tetracoccus (Roxb.) Kurz. is found in Western Ghats of India. Mallotus tetracoccus is one of the medicinally important plants belonging to the family Euphorbiaceae, commonly known as “vatta kanni” in Tamil. In the present study the ethanolic extract of Mallotus tetracoccus has been subjected to GC-MS analysis. The major chemical constituents are Bis (2-ethyl hexyl) phthalate (46.78%),...
Analysis of fatty acid composition in fixed oil extracted from Sterculia foetida Linn. (Sterculiaceae) seed was done with the help of GC-MS. The structural identification was done by preparing FAME of the fixed oil and then subjected to GC-MS wherein Flame Ionization Detector was used. The oil constituted of 7 fatty acids whose carbon chain length, degree and position of unsaturation were determin...
A REVIEW ON PHARMACEUTICAL PREFORMULATION STUDIES IN FORMULATION AND DEVELOPMENT OF NEW DRUG MOLECULES
Preformulation is a group of studies that focus on the physicochemical properties of a new drug candidate that could affect the drug performance and the development of a dosage form. This could provide important information for formulation design or support the need for molecular modification. Every drug has intrinsic chemical and physical properties which has been consider before development of p...
Withania somnifera belongs to the Solanaceaefamily, commonly known as Ashwagandha, Indian ginseng or Winter cherry. It is an important commercial medicinal crop, considered as similar to Panax ginseng in Chinese medicine. Different parts of this plant are used in traditional medicine for the treatment of various ailments. It provides defense against diseases, adverse environmental factors and help...
FOSTERED ANTIARTHRITIC UPSHOT OF MORINGA OLEIFERA LAM. STEM BARK EXTRACT IN DIVERSELY INDUCED ARTHRITIS IN WISTAR RATS WITH PLAUSIBLE MECHANISM
The present research exertion was undertaken to evaluate the antiarthritic effect of methanolic extract of Moringa oleifera Lam stem bark. The extract was subjected to preliminary phytochemical investigation and antiarthritic activity was evaluated with turpentine oil, formaldehyde and CFA induced arthritis. Other parameter like body weight and hematological estimation were carried out.The result ...
To evaluate the in vivo antioxidant activity of alcoholic extract of the roots of Rubia cordifolia (RC). Male mice, were exposed, either to a diet containing 40mg/kg body weight of Pb nitrate or combined with Rubia cordifolia for the first period of 40 days, where the animals were sacrificed for oxidative studies. Ingestion of Pb (NO3)2 was significantly decreased RBC count, WBC count, Hb level ...
The safety and efficacy of a pharmaceutical dosage form can be guaranteed when its quality is reliable. The efficacy of pharmaceutical dosage forms generally depends on their formulation properties, and manufacturing methods, hence it is likely that the quality of dosage form may vary. The aim was to evaluate the quality of paracetamol tablet marketed in Somali region of Ethiopia. The study was ex...
HYPOLIPIDEMIC AND HEPATOPROTECTIVE EFFECTS OF DIFFERENT FRACTIONS OF METHANOLIC EXTRACT OF MOMORDICA CHARANTIA (LINN.) IN ALLOXAN INDUCED DIABETIC RATS
The study was undertaken to investigate the hypolipidemic and hepatoprotective effects of the different fractions (Petroleum ether, ethyl acetate and chloroform) of methanolic extract of Momordica charantia. The different fractions of extract were administered intraperitoneally as a single dose of 150 mg/kg body weight to alloxan induced diabetic rats and found to reduce blood lipid level (Total c...
PHYTOCHEMICAL CONSTITUENTS OF ALOE VERA AND THEIR MULTIFUNCTIONAL PROPERTIES: A COMPREHENSIVE REVIEW
Aloe vera belongs to the family Liliaceae commonly known as Ghrit Kumari, is the ever known oldest and the most applied medicinal plant worldwide. Aloe Vera is used for vigor, wellness and medicinal purposes since rigvedic times. Health benefits of Aloe vera include its application in wound healing, treating burns, minimizing frost bite damage, protection against skin damage from x-rays, lung can...
Aim of the study: Now a days due to the hammering of movies and fashion most of the people specifically age group between 18 to 30 years, are diverted more to have the protein supplements in excess for getting good physique and well toned body shape. The people suppose to eat more calcium, vitamins and some steroids with intension that they will get done the things too fast. Without been having go...