The World Health Organization adopted a major policy change in accepting that most developing nations would have to make use of more traditional medical practices for primary health care. Piper betel L.belongs to family Piperaceae commonly known as Pan. It is extensively grown in Sri Lanka, India, Thailand, Taiwan and other Southeast Asian countries. This oil may be used as an industrial raw mater...
A study was undertaken to evaluate the antioxidant potential of two species of Tinospora viz Tinospora cordifolia and Tinospora sinensis on a comparative basis. Aqueous and ethanolic extracts of both the species were subjected to in vitro antioxidant activity screening models such as DPPH, ABTS, nitric oxide and superoxide radical scavenging activity, inhibition of lipid peroxidation, reduction of...
ANTIMICROBIAL AND ANTIOXIDANT PROPERTY OF COMMONLY FOUND MICROALGAE SPIRULINA PLATENSIS, NOSTOC MUSCORUM AND CHLORELLA PYRENOIDOSA AGAINST SOME PATHOGENIC BACTERIA AND FUNGI
In the present study, three algal species (Spirulina platensis, Chlorella pyrenoidosa and Nostoc muscorum (ATCC 2789) were used to investigate their antimicrobial and antioxidant properties against some human pathogenic bacteria and fungi (Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Micrococcus luteus and fungus Aspergillus luchuensis,...
NEW APPROACHES OF 4-ARYL-2-HYDRAZINOTHIAZOLE DERIVATIVES SYNTHESIS, MOLECULAR DOCKING, AND BIOLOGICAL EVALUATIONS
In the field of the preparation of chemotherapeutic agents with new mechanism distinct from currently approved drugs is important. However, the clinically effective approved small inhibitor molecule is still lacking. Previous reports indicated that 4-aryl-2-hydrazinothiazole derivatives provided a useful start point to develop HAT inhibitors (histone acetyltransferase). Consequently, preparation a...
PHYTOCHEMICAL SCREENING AND ESSENTIAL OIL ANALYSIS OF ONE OF THE PERSIAN SEDGES; CYPERUS ROTUNDUS L.
Phytochemical investigations of tuber extracts and evaluation of the hydro-distilled essential oil, obtained from Cyperus rotundus L. (Cyperaceae Family) growing wild in Isfahan Province (Iran) were studied. Phytochemical surveys revealed the presence of flavonoids, tannins, alkaloids and essential oils. Chemical composition of dried tubers essential oil was also analyzed by GC/MS. Sixty natural c...
BACKGROUND: Self-medication is the selection and use of medicines by individuals to treat selfrecognised illnesses or symptoms and an important initial response to illnesses if successfully used. The objective of this study was to assess knowledge, attitude and practice of self medication among Medical Sciences Faculty students of Jimma University. METHODS: A cross sectional study was conducted...
PHYTOCHEMICAL INVESTIGATION AND CHROMATOGRAPHIC EVALUATION OF THE ETHANOLIC EXTRACT OF WHOLE PLANT EXTRACT OF DENDROPHTHOE FALCATA (L.F) ETTINGSH
The present study was aimed to investigate phytochemicals present in the whole plant extract of Dendrophthoe falcata and development of new solvent system for thin layer chromatography of ethanolic (whole plant) extract of medicinal plant Dendrophthoe falcata. The extract showed presence of Carbohydrates, Sterols, Glycosides, Flavonoids and Phenolic compounds. For TLC, new solvent system developed...
VISUAL ESTIMATION AND SPECTROPHOTOMETRIC DETERMINATION OF TANNIN CONTENT AND ANTIOXIDANT ACTIVITY OF THREE COMMON VEGETABLE
Antioxidant activities of different vegetables Bitter gourd, Tomato and Spinach (Momordica charantia, Lycopersicon esculentum, Spinacia oleracea) were determined. In addition, rapid visual estimation of tannin content, total phenolic, tested for their free radical scavenging activity (FRSA) in the DPPH (1, 1-dephenyl- 2-picrylhydrazil radical) of those samples were assessed. A new technique was us...
PLANTEROSOMES: A POTENTIAL PHYTO-PHOSPHOLIPID CARRIERS FOR THE BIOAVAILABILITY ENHANCEMENT OF HERBAL EXTRACTS
Planterosomes, term “PLANTERO” means plant while “SOME” means cell-like. A novel emerging technique applied to phytopharmaceutical for the enhancement of bioavailability of herbal extract for medicinal applications. Since the two major limiting factors for molecules to pass the biological membrane for their absorption in the blood stream mainly includes lipid solubility and molecular sizes...
Herbs & its formulations have a long history of use in the treatment of human diseases. Herbal extracts have long been regarded as a source of new and useful pharmaceuticals. According to Cragg's investigation, approximately 62 % of commercially available drugs have natural product origins. Manjistha, or Rubia Cordifolia to give it its scientific name, is a branched climber with small, green...