COMPARATIVE STUDY OF RADICAL SCAVENGING ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF FRESH AND DRY RHIZOMES OF CURCUMA ZEDOARIA
Oxygen is an element obligatory for life. Biological combustion produces harmful intermediates called free radicals. Free radicals are continuously produced by the body’s aerobic life and our metabolism. Antioxidants are the substances, which act against oxidative compounds. Under normal conditions the body’s antioxidants convert ROS to prevent the over production of free radicals. Recently, n...
Oral Disintegrating Drug Delivery Systems (ODDDS) have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact with saliva, thus obviating the requirement of water during administration. Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, or...
EVALUATION OF ACUTE TOXICITY OF NEEM ACTIVE CONSTITUENT, NIMBOLIDE AND ITS HEPATOPROTECTIVE ACTIVITY AGAINST ACUTE DOSE OF CARBON TETRACHLORIDE TREATED ALBINO RATS
Objective: To investigate the neem active constituent nimbolide for the evidence of acute toxicity and its protective effects against carbon tetrachloride (CCl4) induced liver toxicity in rats. Materials and Methods: Group allotment in hepatoprotective activity study included vehicle, CCl4 (1ml/kg), Silymarin (100 µg/kg/day) + CCl4 and graded doses of nimbolide (100 and 200µg/ kg/ day) + CCl4...
Background: Job satisfaction represents one of the most complex areas facing today’s managers when it comes to managing their employees. The level of job satisfaction among pharmacy personnel is of importance because it may affect performance and retention. Objective: To assess the level of job satisfaction and factors associated with it among pharmacy professionals working at selected heal...
AN INVESTIGATION ON ANTI DIABETIC MEDICINAL PLANTS USED BY VILLAGERS IN NALBARI DISTRICT, ASSAM, INDIA
Nalbari district is situated in between 26°N and 27oN latitude and 92oE and 97oE longitude. It lies between Kamrup and Barpeta district of lower Assam. Nalbari has a population of 1138184 (2001 census). An ethnobotanical Survey was conducted in 2010 in selected villages to explore the medicinal plant used by the villagers to cure Diabetes. This villages are inhabited by Boros, Koch, Muslim commun...
The plant Tephrosia purpurea L. is commonly known as Unhali. T. purpurea (Leguminosae) is a copiously branched perennial herb. Present work was undertaken to study antioxidant potential of the plant. Dried ethanol and aqueous extracts plant were screened for in-vitro antioxidant activity by DPPH assay and nitric oxide screening methods. Results showed that IC50 value of aqueous extract in DPPH ass...
HEPATOPROTECTIVE AND ANTIOXIDANT EFFECT OF BALANITES AEGYPTIACA (L.) DEL AGAINST CCL4 INDUCED HEPATOTOXICITY IN RATS
The various parts of Balanites aegyptiaca (L.) Del (Balanitaceae) is used in Ayurvedic and other folk medicine for the treatment of various ailments such as syphilis, jaundice, liver and spleen problem, epilepsy and yellow fever. This study was designed to evaluate the hepatoprotective and antioxidant effect of ethanol extract of aerial part of Balanites aegyptiaca on CCl4 induced hepatotoxicity i...
This overview firstly highlights biology of endophytic microbes from medicinal plants as well as their chemistry with emphasis on the important merging of microbiology and natural products chemistry and its role in improving our current knowledge of endophytic associations in medicinal plants. Secondary metabolites of medicinal plants-derived endophytes reported in recent years are grouped accordi...
The human skin serves as an impediment, a thermo regulator and prevents excessive loss of water from the internal organs. Various ways of transferring the drugs have been developed by modifying the barrier properties of the skin. Enhancement in skin penetration by hydration of the stratum corneum, or by use of chemical enhancers acting on the lipids and keratinized structures in the stratum corneu...
The ophthalmic in-situ gels now days proved an palpable sustained drug delivery in various eye diseases. The formulation of in-situ gels for eye which carries the advantages like easy for administration, reduces frequency of dose and improves patient compliance. The formation of in-situ gels depends on phase transition system or sol-gel transition system. The formulation approaches like temperatur...