Molecules greater than 500 Da normally do not cross the skin. This prevents epicutaneous delivery of the high molecular weight therapeutics as well as non-invasive transcutaneous immunisation. Transfersomes are a form of elastic or deformable vesicle, which were first introduced in the early 1990s. Elasticity is generated by incorporation of an edge activator in the lipid bilayer structure. The or...
Endophytic fungi residing inside the medicinal plants are of gaining importance for their bioactive compounds. This present study is undertaken to isolate and identify the potential endophytic fungi from Moringa oleifera, a traditional medicinal plant. A total of 24 segments each 12 from leaf and stem were collected, surface sterilized and was inoculated on to Sabouraud Dextrose Agar (SDA) plates....
A total of thirty endophytic fungi were isolated from leaves and twigs of Eucalyptus globulus and Eucalyptus citriodora. Among thirty endophytic fungal isolates, four (P3MT1, P3MT2, OP4MT2 and P7ML2) are consistently producing compounds which are inhibiting Pseudomonas aeroginosa, Mycobacterium smegmatis and Candida albicans even after 10 generations tested under dual culture, well diffusion and...
The phytochemical analysis of the medicinal plant Kalonchoe pinnata was carried out to evaluate the antioxidant potential. Alcoholic extracts of the leaves was subjected to in vitro antioxidant activity screening models such as inhibition of lipid peroxidation, nitric oxide ,superoxide radical and hydroxyl radical scavenging activity. Ascorbic acid was used as the standard for superoxide anion rad...
IN-VITRO ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF HYDROMETHANOLIC EXTRACT OF AVERRHOA BILIMBI L. FRUITS
Averrhoa bilimbi Linn. (Family: Oxalidiaceae) is a medicinal plant which is extensively used in traditional medicine to cure cough, cold, itches, boils, rheumatism, syphilis, diabetes, whooping cough, and hypertension. In this study, hydromethanolic extract of A. bilimbi fruits was examined for its antioxidant action using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and total antioxid...
Anti cancer activity of four selected mangrove plants Bruguiera gymnorrhiza, Aegiceras corniculatum, Aegialitis rotundifolia and Lumnitzera racemosa against HepG2 cell line was studied. During the present investigation, crude methanol extracts of selected mangrove plants were prepared using soxhlet apparatus. In vitro anti cancer activity of mangrove plant extracts at various concentrations (10 to...
Background: Job satisfaction represents one of the most complex areas facing today’s managers when it comes to managing their employees. The level of job satisfaction among pharmacy personnel is of importance because it may affect performance and retention. Objective: To assess the level of job satisfaction and factors associated with it among pharmacy professionals working at selected heal...
PHYTOCHEMICAL ANALYSIS OF TINOSPORA CORDIFOLIA (WILLD.) MIERS EX HOOK. F. & THOMS STEM OF VARIED THICKNESS
Tinospora cordifolia (Giloe/Guduchi) belonging to the family menispermaceae, is a large extensively spreading glabrous, perennial deciduous twiner with succulent stems and papery bark. It is widely used in Ayurvedic system of medicine “Rasayanas” to the immune system and the body resistance against infections. In modern medicine, T. cordifolia is used for the treatment of general weakness, fev...
HEPATOPROTECTIVE AND ANTIOXIDANT EFFECT OF BALANITES AEGYPTIACA (L.) DEL AGAINST CCL4 INDUCED HEPATOTOXICITY IN RATS
The various parts of Balanites aegyptiaca (L.) Del (Balanitaceae) is used in Ayurvedic and other folk medicine for the treatment of various ailments such as syphilis, jaundice, liver and spleen problem, epilepsy and yellow fever. This study was designed to evaluate the hepatoprotective and antioxidant effect of ethanol extract of aerial part of Balanites aegyptiaca on CCl4 induced hepatotoxicity i...
The manufacture of bi-layer tablets, produced by the sequential compaction of loose powder layers has recently become of increased interest within the pharmaceutical industry due to the tailored release profiles of active ingredients that may be obtained. In a bi-layer configuration, the immediate release layer of the bi-layer tablet has worked as the loading dose and the sustained release layer h...