Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
PHYTOCHEMICAL ANALYSES, ANTIBACTERIAL, IN VITRO ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF ETHANOLIC EXTRACT OF SYZYGIUM CUMINI (L.) SEED EXTRACT
Phytochemical constituents present in the aqueous and ethanolic extract of Syzygium cumini seeds were investigated which were found to be responsible for its medicinal efficacy. The major phytoconstituents present in S. cumini seeds were further determined by GCMS analysis which showed the presence of polyphenols, sesquiterpenes, n-alkanes. The antibacterial activity of ethanolic extract of S. cum...
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A SIMPLE UV SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF FEBUXOSTAT IN BULK AND PHARMACEUTICAL FORMULATIONS
A simple and cost effective spectrophotometric method is described for the determination of febuxostat in pure form and in pharmaceutical formulations. The drug was highly soluble in methanol so it was selected as the solvent system for the drug. This ensured adequate drug solubility and maximum assay sensitivity. The linearity range for febuxostat at its wavelength of detection of 315 nm was obta...
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NANOSPONGE LOADED HYDROGEL OF CEPHALEXIN FOR TOPICAL DELIVERY
Cephalexin is a first generation cephalosporin antibiotic which is used for the treatment of skin and soft tissue infection, urinary tract infection and diabetic foot infection. Since cephalexin is not available as topical formulation, cephalexin was formulated into nanosponge loaded hydrogel as it can enhance skin permeation. Nanosponges of cephalexin were prepared using hydroxyl ethyl cellulose ...
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PHOSPHATIDYLCHOLINE: A REVOLUTION IN DRUG DELIVERY TECHNOLOGY
In recent years Phosphatidylcholine has greatly impacted the drug delivery technology. The very first and most important advantage of phospholipid based vesicular system is the compatibility of phospholipids with membrane of human either internal membrane as well as skin (external membrane). For a drug to be absorbed and distributed into organs and tissues and eliminated from the body, it must pas...
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ACE INHIBITORS: A COMPREHENSIVE REVIEW
Hypertension is a chronic increase in blood pressure, characterized as primary and secondary hypertension. The disorder is associated with various risk factors like obesity, diabetes, age, lack of exercise etc. Hypertension is being treated since ancient times by Ayurvedic, Chinese and Unani medicine. Now various allopathic drugs are available which include diuretics, calcium channel blockers, α-...
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IN SITU GEL FORMING INJECTABLE DRUG DELIVERY SYSTEM
Recently, controlled and sustained drug delivery has become the standard in modern pharmaceutical design and an intensive research have been undertaken in achieving much better drug product effectiveness, reliability and safety. This interest has been sparked by the advantages shown by in situ gelforming drug delivery systems such as ease of administration and reduced frequency of administration, ...
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ISOLATION AND CHARACTERIZATION OF BIOACTIVE ACTINOMYCETES FROM SOIL IN AND AROUND NAGPUR
ABSTRACT: Fifteen soil samples were collected from different locations near Nagpur i.e. from Nagpur, Bhandara and Chandrapur. Air drying and pre-treatment of soil samples with CaCo3 (1%) were found to be most effective for isolation of actinomycetes. Five different selective media were used for the isolation of actinomycetes and the best growth was observed in yeast malt extract agar medium with 1...
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OPTIMIZATION OF THE FORMULATION AND IN-VITRO EVALUATION OF CAPECITABINE NIOSOMES FOR THE TREATMENT OF COLON CANCER
The goal of the present study was to investigate the feasibility of using non-ionic surfactant vesicles as carriers for the sustained delivery of water soluble anti-cancer drug Capecitabine, used in the treatment of colorectal cancer. The niosomal formulations were prepared using various non-ionic surfactants (span 40, span 60, tween 40 and tween 60) in the presence of cholesterol, by thin film hy...
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GAS CHROMATOGRAPHY AND MASS SPECTROMETRY ANALYSIS OF SOLANUM VILLOSUM (MILL) (SOLANACEAE)
In the present study the bioactive compounds of Solanum villosum leaves extract were used to evaluate by GC – MS method. 50g of fine powder was packed with No.1 Whatman filter paper and placed in soxhlet apparatus along with ethanol. The crude extract were collected and dried at room temperature, 30˚C after which yield was weighed and then performed to GC-MS analysis. The Ethanol leaf extrac...
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PRELIMINARY PHYTOCHEMICAL ANALYSIS OF AEGLE MARMELOS, RUTA GRAVEOLENS, OPUNTIA DELLINI, EUPHORBIA ROYLEANA AND EUPHORBIA ANTIQUORUM
Plants are the local heritage with global importance. World is endowed with a rich wealth of medicinal plants. They represent and alternative treatment of non-serve cases of infections diseases. They are also the essential an integral part in complementary and alternative medicine and due to they which have developed the ability for the formation of various phytochemicals like terpenoids, steroids...
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