IN-VITRO ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF HYDROMETHANOLIC EXTRACT OF AVERRHOA BILIMBI L. FRUITS
Averrhoa bilimbi Linn. (Family: Oxalidiaceae) is a medicinal plant which is extensively used in traditional medicine to cure cough, cold, itches, boils, rheumatism, syphilis, diabetes, whooping cough, and hypertension. In this study, hydromethanolic extract of A. bilimbi fruits was examined for its antioxidant action using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and total antioxid...
Anti cancer activity of four selected mangrove plants Bruguiera gymnorrhiza, Aegiceras corniculatum, Aegialitis rotundifolia and Lumnitzera racemosa against HepG2 cell line was studied. During the present investigation, crude methanol extracts of selected mangrove plants were prepared using soxhlet apparatus. In vitro anti cancer activity of mangrove plant extracts at various concentrations (10 to...
COMPARATIVE STUDY OF RADICAL SCAVENGING ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF FRESH AND DRY RHIZOMES OF CURCUMA ZEDOARIA
Oxygen is an element obligatory for life. Biological combustion produces harmful intermediates called free radicals. Free radicals are continuously produced by the body’s aerobic life and our metabolism. Antioxidants are the substances, which act against oxidative compounds. Under normal conditions the body’s antioxidants convert ROS to prevent the over production of free radicals. Recently, n...
ASSESSMENT OF CYTOTOXIC ACTIVITY OF TWO MEDICINAL PLANTS USING BRINE SHRIMP (ARTEMIA SALINA) AS AN EXPERIMENTAL TOOL
Solanum sisymbriifolium (Solanaceae) and Jatropha gossypifolia (Euphorbiaceae) have long been used in folkloric medicine for the treatment of various ailments. The purpose of the present study was to evaluate the cytotoxic activity of the plants and to make available the process of data analysis of cytotoxic studies to the researchers. A general toxicity of the extracts was assessed by a simple an...
Nyctanthes arbor-tristis Linn. (NAT) is well known Indian medicinal plant. The plant is used in Ayurveda for various pharmacological actions such as anti-arthritic, antispasmodic, antibacterial, anti-inflammatory, immunostimulant, antidiabetic, hepatoprotective, antiarthritic, antioxidant, antimicrobial, antihelmintic, antileishmanial, antiviral, CNS depressant. The present review discusses phar...
Salvia L., is one of the largest genera from Lamiaceae (Labiatae) family which comprises 900 species and is widely distributed in various regions of the world like in America, Europe, Asia. In this review article, the triterpenoid constituents were investigated from all of the Salvia plants to date are reported. About 214 triterpenoids of different classes were isolated and characterized from 113 ...
The aspire of the present research was to explore the hypoglycemic, analgesic and anti-inflammatory activity of ethyl acetate extract of Peporemia pellucida in alloxan-induced diabetic mice, Acquired immune deficiency syndrome (AIDS), and hypercholesterolemia and against pain. In the present study hypoglycemic effect of the ethyl acetate extract of Peperomea pellucida was significant from (25.35 t...
The present study was conducted to evaluate the hepato-protective activity of methanol extract of seeds of Trigonella foenum graecum (TFG)in CCl4 induced toxicity in Wistar albino rats. Seeds of TFG were collected, and subjected to continuous cold maceration in a macerator, for 72 h with solvents like petroleum ether (60 – 80) and methanol separately. Hepatic injury in rats was induced separatel...
Introduction: Nephrotic syndrome is the most common chronic glomerular diseases in children. The most common infection in children with nephrotic syndrome is urinary tract infection. The aim of this study was to evaluate the prevalence of urinary tract infection in children with nephrotic syndrome and to prepare and submit an appropriate protocol regarding the necessity and method of UTI examinati...
The oral delivery of lipophilic drugs presents a major challenge because of the low aqueous solubility and less bioavailability. Self-micro emulsifying drug delivery systems (SMEDDSs) have gained exposure for their ability to increase solubility and bioavailability. SMEDDS, which are isotropic mixtures of oils, surfactants, solvents and co-solvents/surfactants, can be used for the design of formul...