Periodontitis is a common and widespread disease, which occurs due to the pathogenic bacterial infections (like Porphyromonas gingivalis, Bacteroides spp., E. coli, Staphylococcus aureus, S. mutans etc.) established within the gingival sulcus. This condition, when not arrested, will cause formation of periodontal pocket. In order to eliminate or control the disease and arrest further periodontal t...
Amaranthus vegetable and seeds are highly nutritious. Four species of Amaranthus were planted in pots in a glass house and leaves were harvested. Fresh leaves were analyzed for protein and carbohydrate content and oven dried leaves for Fe, Ca, K and Na contents. Protein content was varied from 6.10-9.00g/100g of fresh leaves. The amount of carbohydrate in fresh leaves of all four species varied fr...
High performance liquid chromatography is one of the most accurate methods widely used for the quantitative as well as qualitative analysis of drug product and is used for determining drug product stability. Stability indicating HPLC methods are used to separate various drug related impurities that are formed during the synthesis or manufacture of drug product. This article discusses the strategie...
More than 50% of pharmaceutical products are orally administered for several Reasons and undesirable taste is one of the important formulation problems that is Encountered with such oral products. Taste of a pharmaceutical product is an important parameter governing compliance. Hence taste masking of oral Pharmaceuticals has become important tool to improve patient compliance and the Quality of tr...
Learning is the process of acquisition of information and skills, while subsequent retention of that information is called memory. Learning and memory together called as cognition. Also, memory is a process involving encoding, storing, and recalling information. Thus, memory records various facts and events, make it available for further use, and hence can be considered as most valuable health ass...
A budding interest in Nanopharmaceuticals had generated a number of advancements throughout recent years with a focus on engineering novel applications. Nanophytomedicines are prepared from active phytoconstituents or standardized extracts. The world market for nanomedicine is estimated to reach $130.9 billion by the fiscal year 2016. Liposome nanoparticle (NP) with entrapped doxorubicin was repor...
Oral Disintegrating Drug Delivery Systems (ODDDS) have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact with saliva, thus obviating the requirement of water during administration. Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, or...
ANTIDIABETIC, ANTIHYPERLIPIDAEMIC AND ANTIOXIDANT ACTIVITY OF WATTAKAKA VOLUBILIS (L. F) STAPF LEAVES IN ALLOXAN INDUCED DIABETIC RATS
The ethanol extract of Wattakaka volubilis (L. f) Stapf. (Family: Asclepiadaceae) leaf was investigated for its antidiabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg, i.p). The ethanol extract of Wattakaka volubilis at a dose of 150mg/kg of body weight was administered at single dose per day to diabetes induced rats for a ...
HYPOGLYCEMIC AND ANTIHYPERGLYCEMIC EFFECT OF ETHANOLIC EXTRACT OF WHOLE PLANT OF LAWSONIA INERMIS (HENNA) IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Diabetes, a global burden, is characterized by fast elevation of blood sugar level. The incidence of diabetes mellitus is rising all over the world, especially in Asia. Many oral hypoglycemic agents, such as biguanides and sulphonylurea are available along with insulin for the treatment of diabetes mellitus but they have significant side effects and sometimes they are found to be ineffective in ch...
BIOCHEMICAL AND ANTIMICROBIAL STUDY OF BOERHAVIA ERECTA AND CHROMOLAENA ODORATA (L.) KING & ROBINSON
Purpose: The present study was designed to evaluate the phytochemical, biochemical and antimicrobial activity of leaf extracts of Boerhavia erecta and Chromolaena odorata. Methods: The leaves of Boerhavia erecta and Chromolaena odorata were washed with tap water followed by distilled water. The cleaned leaves were shade dried and then made to fine powder by using homogenizer. Ab...