COMPARATIVE STUDY ON THE EFFECT OF DIFFERENT METHODS OF DRYING ON PHENOLICS CONTENT AND ANTIOXIDANT ACTIVITY OF SOME EDIBLE PLANTS
Antioxidants have important role in prevention and treatment of disorders and plants are considered as rich sources of radical scavenging compounds. Nowadays, many herbs are used in dried form which is possible to affect their antioxidant activity. In the present investigation, the effects of different drying methods on the antioxidant capacity and total phenolics content of some culinary plant sp...
Amaranthus vegetable and seeds are highly nutritious. Four species of Amaranthus were planted in pots in a glass house and leaves were harvested. Fresh leaves were analyzed for protein and carbohydrate content and oven dried leaves for Fe, Ca, K and Na contents. Protein content was varied from 6.10-9.00g/100g of fresh leaves. The amount of carbohydrate in fresh leaves of all four species varied fr...
ANTIDIABETIC, ANTIHYPERLIPIDAEMIC AND ANTIOXIDANT ACTIVITY OF WATTAKAKA VOLUBILIS (L. F) STAPF LEAVES IN ALLOXAN INDUCED DIABETIC RATS
The ethanol extract of Wattakaka volubilis (L. f) Stapf. (Family: Asclepiadaceae) leaf was investigated for its antidiabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg, i.p). The ethanol extract of Wattakaka volubilis at a dose of 150mg/kg of body weight was administered at single dose per day to diabetes induced rats for a ...
BIOCHEMICAL AND ANTIMICROBIAL STUDY OF BOERHAVIA ERECTA AND CHROMOLAENA ODORATA (L.) KING & ROBINSON
Purpose: The present study was designed to evaluate the phytochemical, biochemical and antimicrobial activity of leaf extracts of Boerhavia erecta and Chromolaena odorata. Methods: The leaves of Boerhavia erecta and Chromolaena odorata were washed with tap water followed by distilled water. The cleaned leaves were shade dried and then made to fine powder by using homogenizer. Ab...
An accurate, precise and rapid RP-HPLC method was developed and subsequently validated for the determination of Empagliflozin in API. Better separation of the drug was achieved on Intersil column(150x40mm, 5 μm) with the mobile phase consisted of mixture of 0.01 M acetate buffer, methanol in ratio of (30:70v/v ) at flow rate of 2ml/min, with detection at 260nm using PDA detector. The retention...
Oral Disintegrating Drug Delivery Systems (ODDDS) have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact with saliva, thus obviating the requirement of water during administration. Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, or...
NEW APPROACHES OF 4-ARYL-2-HYDRAZINOTHIAZOLE DERIVATIVES SYNTHESIS, MOLECULAR DOCKING, AND BIOLOGICAL EVALUATIONS
In the field of the preparation of chemotherapeutic agents with new mechanism distinct from currently approved drugs is important. However, the clinically effective approved small inhibitor molecule is still lacking. Previous reports indicated that 4-aryl-2-hydrazinothiazole derivatives provided a useful start point to develop HAT inhibitors (histone acetyltransferase). Consequently, preparation a...
HYPOGLYCEMIC AND ANTIHYPERGLYCEMIC EFFECT OF ETHANOLIC EXTRACT OF WHOLE PLANT OF LAWSONIA INERMIS (HENNA) IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Diabetes, a global burden, is characterized by fast elevation of blood sugar level. The incidence of diabetes mellitus is rising all over the world, especially in Asia. Many oral hypoglycemic agents, such as biguanides and sulphonylurea are available along with insulin for the treatment of diabetes mellitus but they have significant side effects and sometimes they are found to be ineffective in ch...
Objective: The study was designed to evaluate the efficiency of pharmaceutical care on the control of clinical parameters, such as fasting glycaemia and glycosylated haemoglobin also to assess drug therapy problems in patients with type 2 diabetes mellitus. Setting: the study was conducted at Diabetic Center in Sulaimany/Iraq, during 18 September 2010 -20 January 2011. Methods: A prospective an...
Cinnamaldehyde is derived from the cinnamon essential oil (EO) having many biological and pharmacological significance. This review article explains the source, chemistry, physico-chemical characteristics of the molecule. The synthesis of its different analogous has been duly highlighted. The different applications narrating the various usage have been reported. It is expected that this review sha...