Posted by admin on Sep 30, 2025 in |
Cardiac electrophysiology has undergone significant advancements in recent decades, revolutionizing the diagnosis and treatment of heart rhythm disorders. This narrative review explores the integration of diagnostic and therapeutic approaches in modern arrhythmia management. We discuss the evolution of electrophysiology studies, highlighting their crucial role in guiding ablation procedures and treatment planning. The review examines radiofrequency ablation techniques, their mechanisms of action, and outcomes across various arrhythmia types. We also explore the progress in pacemaker technology, from traditional devices to leadless and physiological pacing systems. The synergistic use of these technologies in clinical practice is emphasized, demonstrating how their integration enhances patient care. We analyze patient outcomes, comparing the effectiveness of medical and interventional approaches, and discuss long-term safety and efficacy data. The review addresses special considerations for pediatric and elderly populations, as well as patients with comorbidities. Cost-effectiveness and resource utilization in electrophysiology procedures are also examined. Looking to the future, we highlight emerging technologies and approaches, including advanced mapping systems, novel energy sources for ablation, and the potential...
Read More
Posted by admin on Sep 30, 2025 in |
Ayurveda is the traditional frame of health care known since old times. Dracaena reflexa is a plant of the Asparagus family with a few important phytochemical constituents utilized to treat different illnesses. In particular, its uses were widely employed in the traditional system of medicine. The present review was pointed to evaluate the phytochemistry, pharmacological properties, botanical description and microscopic characteristics of Dracaena reflexa leaves. The plant has a reliable number of important phytochemical constituents that are utilized as medications in different illness. Preparatory subjective phytochemical screening of Dracaena reflexa leaves extracts showed the presence of number of phytoconstituents such as alkaloids, flavonoids, terpenoids, saponins, amino acids, tannins, steroids, glycosides, carbohydrates and fats. Presence of these compounds contribute to the plant’s potential therapeutic properties, including antioxidant, pain relieving, anticonvulsant, anti-inflammatory, antimicrobial activities and wound healing properties. Further research into the pharmacological potential of Dracaena reflexa may reveal its therapeutic benefits. Various research findings suggested that Dracaena reflexa might be a valuable herbal medicine for a range of sicknesses, both...
Read More
Posted by admin on Sep 30, 2025 in |
Chewable tablets are produced using various manufacturing processes, each with its own unique characteristics and advantages. The most common method includes wet granulation, dry granulation, direct compression, extrusion, melt granulation, fluid bed granulation, compression coating, 3D printing. Each process offers distinct benefits, such as improve tablet strength better taste masking and increased manufacturing efficiency. The choice of process depends upon the specific formulation, desired tablet characteristic and production scale. Chewable tablets are designed to be easily broken down in the mouth, but their texture and hardness can vary significantly, affecting patient acceptability and compliance. The CDI is a reliable and valid tool for evaluating the chewability of chewable tablets. It can be used by manufacturers to optimize tablet formulation and design, and by regulatory agencies to set standards for chewable tablet...
Read More
Posted by admin on Sep 30, 2025 in |
Bio-nanotechnology has emerged as an integration of biotechnology and nanotechnology. The nanoparticles are described as particles with sizes ranging from 1 to 100 nanometers. Nanoparticles exist in many forms such as spherical, cylindrical, platelets, tubes, etc. Nanotechnology is an area that is flourishing, creating an effect in all fields of human life. Biological synthesis employs plant leaf extract, bacteria, fungi, and enzymes to synthesize nanoparticles offers various benefits of eco-friendliness and compatibility for pharmaceutical and other biomedical applications as they do not use toxic chemicals. Drugs are entrapped in the polymer matrix particulates or solid solutions or may be bound to the particle surface by physical adsorption or through chemical interaction. The basic concept involved is the selective and effective localization of nanodrugs in appropriate concentration, and nanoparticles provide restricted access to non-target cells. Nanoparticles are mainly taken by the reticuloendothelial system after administration. Therefore, nanoparticles are useful for carrying drugs to the phagocytically active cells. It is possible to enhance drug delivery to targeted tissues by modifying the...
Read More
Posted by admin on Sep 30, 2025 in |
Antimicrobials are vital agents that combat dangerous microorganisms, but increasing resistance to these drugs is a major challenge to global health security. AMR occurs when the intended killing drugs lose their effectiveness because pathogens have learned how to adapt and become resistant to them mainly as a result of overusing, misusing or using antibiotics in ways that are not suitable. Adhering with this pressing matter necessitates fresh methods coupled with an all-inclusive perspective. Literature was searched through indexed databases including Scopus, PubMed, Google Scholar and Science director. Research on novel AMR treatments is continuing. Anti-virulent therapy targets bacteria’s virulence factors rather than eradicating them, preventing antibiotic-resistant strains. Naturally occurring or manufactured antimicrobial peptides have diverse modes of action and little resistance risk. Using antimicrobials to prevent infections reduces the need for curative antibiotics. Bacteriophage therapy employs viruses that infect and kill bacteria to treat illnesses. Plant derivatives like phytochemicals and nanoparticles are antimicrobial.Review addressing the challenge of antimicrobial resistance requirements and for multi-pronged approach, including surveillance, stewardship and development...
Read More
