Posted by admin on Jun 30, 2022 in |
Medicinal plants provide numerous benefits to human health. Mussaenda frondosa Linn belongs to the Rubiaceae family, which has 500 genera and 5300 medicinal plant species. Mussaenda is a flowering plant genus with many beautiful species. Ayurveda, an ancient Indian healing system, describes many herbs, oils, and minerals. People have known about plants’ medicinal value since prehistoric times. Mussaenda contains many medicinal natural compounds such as steroids, triterpenes and flavonoids. The chief chemical constituent present in the whole plant is butanedioic acid, diethyl ester, caryophyllene, hexadecanoic acid, quinic acid, 4-((1E)-3-Hydroxy-1-propenyl)-2-methoxyphenol, Naphthalene, decahydro2-methoxy, 1, 2, 3-Benzenetriol, alkaloids, flavonoids, saponins and tannins. Mussaenda frondosa nanocomposite enhances bioavailability and therapeutic potential. The present review compiled data on the importance of plants and their treatment options. This paper will be very useful to those in the medical, therapeutic, pharmacognosy and pharmacology fields. This article examines the genus Mussaenda and its phytochemical and pharmacological properties....
Read More
Posted by admin on Jun 30, 2022 in |
Xanthene (or 9H-xanthene) is a parent active compound in which a pyran ring is combined with a benzene ring on both sides, whereas in thioxanthene, the oxygen of xanthene is replaced by a sulphur atom. Xanthene and thioxanthene are important classes of organic compounds which exhibit diverse pharmacological activities such as anti-spasmodic, anti-parkinsonian, anti-psychotic, anti-rhinitic, anti-inflammatory, anti-asthmatic, anti-ulcer, etc. This review covers various methods of synthesis of Xanthene and Thioxanthene. The pharmacoeconomic consideration of various marketed products of Xanthene and Thioxanthene are also discussed. It also covers the ongoing clinical trials of the upcoming Xanthene and Thioxanthene-based products and the newer indication of existing drugs. This review would be of immense use to researchers interested in Xanthene and Thioxanthene-based drugs. This review also helps the physician to preferably prescribe the cheaper brand for the patient’s benefit with the help of pharmacoeconomic analysis discussed in the...
Read More
Posted by admin on Jun 30, 2022 in |
The Greek words “angeion” (vessel) and “sperma” (seed) constitute angiosperm which together define enclosed seeds. The angiosperms differ from closely related gymnosperms in seed being naked and not enclosed within a fruit. Moreover, angiosperms are distinguished plants having colorful flowers. Having originated about 130 million years ago, the flowering plants are more diverse and largest among the prominent vegetation. While pteridosperms have been proposed as ancestors of angiosperms, they are the youngest and most recent group of plants having controversies over their origin and are still a hot topic of debate for botanists. Our present investigation is focused on valuing and conserving our beautiful but neglected bioresource that gets blown away or wiped out instead of conservation. From high mountain peaks to sea level and from desert to freshwater, almost all habitats are acquired by flowering plants. The present review signifies the importance of flowering plants in different medicinal aspects. The present literature reveals how researchers have worked on different concepts of flowering plants using petals of flowers as...
Read More
Posted by admin on Jun 30, 2022 in |
The epidemiology, pathophysiology, clinical capabilities, diagnosis and scientific route of rheumatoid arthritis (RA) and the function of disorder-editing anti-rheumatic tablets (DMARDs) in its remedy are reviewed. RA, a giant disorder affecting humans of all races and sexes around the sector, has an unknown and perhaps multifactorial etiology. Conflicting proof supports RA’s immune-complex, infectious, metabolic, or genetic foundation. The sickness impacts arthrodial joints and starts as an immune reaction to unknown antigenic stimuli. A proliferative process ensues, leading to the formation of a vascular lesion referred to as a pannus, which then infiltrates into cartilage, subchondral bone, and tendon. This detrimental segment ends in traditional RA signs of pain, the predicament of motion, swelling, warmth, and redness of the affected joint. Symptoms and laboratory checks form the basis for prognosis. For maximum RA sufferers, a conservative remedy presents a significant advantage. More competitive intervention is vital to prevent everlasting incapacity in those sufferers who suffer from unrelenting and regularly negative sickness. The DMARDs are reserved for treatment of this institution...
Read More
Posted by admin on May 31, 2022 in |
As new treatments and medication are growing rapidly, neurologists are also toward expanding treating patients with idiopathic Parkinson’s disease and facing questions regarding cannabis as a treatment elective, particularly for levodopa-safe Parkinson’s symptoms. Cannabinoids compounds like delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) are the most abundant chemicals present. Whereas THC is psychotropic chemical that tends to cause individuals to feel “high,” while CBD is no psychotropic chemical. Nonetheless, other than cannabis, plant cannabinoids are also produced by the mammalian body, called endocannabinoids. Endocannabinoids are neurotransmitters that bind to cannabinoid receptors and cannabinoid receptor proteins expressed throughout the central nervous system, including the brain and peripheral nervous system. So, these endocannabinoid receptors can be of two types cannabinoid receptor 1 (CB1R) and cannabinoid receptor 2 (CB2R), which are G-protein coupled receptors. The first receptor, CB1R receptors are particularly abundant in the hippocampus, frontal cortex, basal ganglia, hypothalamus and cerebellum, spinal cord and peripheral nervous system. They can also be found in inhibitory GABA-ergic neurons and excitatory glutamatergic neurons. Whereas CB2R receptor...
Read More
