Posted by admin on May 31, 2025 in |
In recent days some groups are seeking infertility treatment, on the other hand there are groups seeking contraception methods. Nowadays there are several ways are available for contraception such are Oral contraceptive pills, implants, injectable, patches, rings, intra uterine devices, Male and Female sterilization and so on. WHO stated that the number of women desiring to use family planning has increased markedly over the past two decades from 900 million in year 2000 and 1.1 billion in the year 2021. Between 2000 to 2020 the contraceptive prevalence rate increased from 47.7 to 49%. WHO assists countries to adapt and implement contraception tools to strengthen contraceptive policies and programs. Siddhars, who were the founders of Siddha Medicine. From their insights they told lot of medicines for all health ailments. Even for disease prevention, diagnosis and to cure the disease. Siddha literature evidenced that the natural contraception method by using herbal drugs which would be effective. Poovarasan (Thespesia populnea) tree bark, Induppu (Rock or pink salt) and Kaaichukatti (Acacia catechu) taken...
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Posted by admin on May 31, 2025 in |
Controlling the crystal growth in a crystallization set up is a complex and time taking process. In the domain of pharmaceutical set up, crystal differences will largely affect the drug performance and stability. Therefore, it is essential to control the crystallization process and optimize the experimental set up to get desired particle characteristics. Process Analytical Technology (PAT) tools are becoming popular for real-time monitoring and control of crystallization process. These tools are endorsed by regulatory bodies such as Food and Drug Administration in pharmaceutical manufacturing enabling consistent product quality and regulatory compliances. This review is not very exhaustive in nature but provides an overview of the crystallization processes and implications on crystal nucleation and growth. Various available PAT tools and their role in optimizing crystallization process have been discussed. Representative case studies employing PAT tools for monitoring pharmaceutical crystallization have been reviewed and their panoramic view depicted in tabular form. Besides, the challenges associated with the PAT tools in large scale manufacturing have also been touched. PAT in crystallization...
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Posted by admin on May 31, 2025 in |
Lumpy skin disease (LSD) causes enormous economic losses in the livestock business. Lumpy skin disease virus (LSDV) a member of the Poxviridae family causes the condition. The Neethling strain is the pro to type. LSDV is part of the Capri poxvirus genus which also includes sheep and goat poxviruses. LSD is an enzootic illness that causes skin nodules and is seldom lethal in cattle. Cattle and water buffalo are the only animals afflicted with substantial morbidity but moderate mortality rates. However, calves are more likely to die. LSD can lead to reduced milk and beef production, miscarriages in females and sterility in males. LSD originated from Zambia in 1929. LSD is considered an endemic disease in Africa. However, in 1984 the disease spread beyond Africa. It has been documented in Madagascar, as well as in various Arab Gulf Peninsula and Middle Eastern countries. The disease has recently been reported in LSD-free nations (Jordan, Syria, Lebanon, Turkey, Iran, and Iraq), potentially causing economic losses in the livestock business. This review...
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Posted by admin on May 31, 2025 in |
Hernia repair is one of the most common surgeries, with recent advancements in mesh technology and surgical techniques significantly improving outcomes. Mesh implants are the standard for reinforcing abdominal walls, reducing recurrence rates compared to traditional sutures. However, complications like chronic pain, infection, and adhesions have driven innovations in mesh development. Modern synthetic meshes are designed to enhance biocompatibility, featuring lightweight, macro-porous structures to promote tissue integration while minimizing complications. Biologic meshes, derived from human or animal tissue, support tissue regeneration and gradually degrade, reducing long-term foreign body reactions. Hybrid meshes combine the durability of synthetics with the regenerative qualities of biologics, offering superior performance in complex repairs. Tailored approaches, including 3D-printed and custom-made meshes, are gaining popularity for their ability to match individual anatomy, minimizing complications such as displacement. Future developments focus on anti-adhesion coatings and bioactive meshes capable of releasing antimicrobial agents to address postoperative issues like adhesions and infections. Despite these advancements, challenges remain in selecting the optimal mesh type and technique for each patient. Financial...
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Posted by admin on May 31, 2025 in |
Hypertension (HTN), a major global health concern and the primary cause of cardiovascular disease (CVD) death is expected to impact 29% of all adults by 2025. Hypertension (HTN) is a multifactorial condition, arising from the complex interaction of hereditary, environmental, and physiological variables that contribute to elevated systolic and diastolic blood pressure. It is frequently caused by dysregulation of blood pressure control mechanisms, such as over activity of the renin-angiotensin system and increased sympathetic nervous system activity. Traditional hypertension therapies, such as ACE inhibitors and beta-blockers, have drawbacks, including low solubility and absorption. As a result, researchers are increasingly focusing on novel treatment approaches, such as medicinal plants and nanotechnology. Herbal plants such as Ashwagandha, Cat’s Claw, Ginger, Ginseng, Murungai, and Touch-Me-Not belonging to different families are renowned for pharmacological activities and have shown potential medicines antihypertensive properties, which are often attributed to their bioactive constituents. Recent breakthroughs in nanotechnology have permitted the manufacture of nanoparticles derived from these plants, improving their stability, bioavailability, and potency. These plant-mediated nanoparticles...
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