Posted by admin on Jan 31, 2022 in |
Diabetes Mellitus, a chronic metabolic disorder, is prevalent all over the world nowadays. As a result, it is estimated that it can become an epidemic in some parts of the world soon. The number of affected people could be as double as that of the currently affected patients till the next decade. In order to fulfill the increasing demands of newer, safer, and more effective medications for treatment, prevention, diagnosis, and mitigation of this condition, companies all over the world are trying to introduce new medications in the market. Before entering the market, any new drug undergoes several clinical trials and tests to check and ensure its safety and efficacy. All the associated Adverse Drug Reactions are supervised and monitored by Pharmacovigilance Centers. This ensures that the patients receive safe and effective treatment with minimum or no undesired effects. A brief overview of commonly used hypoglycemic agents and their associated ADRs obtained from publishing data is elucidated in this...
Read More
Posted by admin on Jan 31, 2022 in |
In the recent advancement of the food and pharmaceutical industry, the encapsulation process has gained interest in the production of functional food and the sustained release of drugs to the target site. The designing and the fabrication of micro or nanocapsule has become the active field of research over the few decades. Encapsulation increases the shelf life of the bioactive materials, increases their stability and protects the bio-actives from the harsh environment. Therefore, the encapsulation process has a great potentiality in the development of functional food and drugs. Many bioactive materials, oils, probiotics, and drugs are encapsulated in a microcapsule made up of varieties of polymeric and non-polymeric substances. Successful encapsulation of materials depends on the choice of the wall materials and the correct techniques adopted for the formation of the microsphere. In this review, an attempt has been made to discuss the different materials and the techniques used in the encapsulation process with reference to the food and pharmaceutical...
Read More
Posted by admin on Jan 31, 2022 in |
Although the human eye has multiple physical and chemical barriers to save itself from foreign materials, there are certain times when an attack on the ocular surface may lead to trauma and/or growth of microbial flora, which can be proved lethal if left untreated. However, certain allopathic treatments and therapies are available; still, there is an increased need for herbal medicines because they have lesser side effects and effective therapeutic value. This review paper identifies different types of ocular infections, how to differentiate between them through signs and symptoms, and different types of herbs used for ocular...
Read More
Posted by admin on Jan 31, 2022 in |
Human Immunodeficiency Virus or HIV is generally known, is a unique type of virus (retrovirus). HIV is a slow virus that causes acquired immunodeficiency syndrome, a human condition in which the progressive failure of the immune system allows opportunistic infections and life-threatening cancers to spread. Retroviruses are a single positive susceptible RNA virus with a DNA mediator and binding parasite targeting a host cell. Retroviruses have risen to prominence in human pathology through their recent association with leukemia and acquired immunodeficiency syndrome (AIDS). This virus infects species of vertebrates ranging from fish to primates and can cause various types of malignancies, homeopathy, immune diseases, and neurodegenerative diseases. Since the Peyton Rous experimented more than 70 years ago, animal retroviruses have served as models for viral carcinogenesis, with oncogenes being discovered for the first time. The central goals of retrovirology today are the treatment and prevention of human and non-human diseases and the use of this virus in research. Recent studies have shown that retroviruses can be used in several...
Read More
Posted by admin on Jan 31, 2022 in |
Topical drug delivery is the conventional route of drug administration to the surface of the skin. Barrier present in the various layers of skin hinders the permeability of drug molecules, specifically large size of drug substance into the systemic circulation. A small-sized needle in micron range is found to be a promising approach to penetrate the uppermost layer of the skin i.e., epidermis to the dermal tissue. These needles are used in the delivery of drugs such as insulin, proteins, RNA and gene therapy due to the efficiency, convenience, safety, and painless nature of the needle. Moreover, the combination of non-carriers with the microneedle delivery system further highlights the application of these needles. This review will discuss the various types of microneedles (MNs) such as coated, solid, dissolving hollow and hydrogels for the effective delivery of drugs and the materials used as fabrication of microneedles. All the microneedles act differently to show its action such as solid MNs produce mini pores in the skin, whereas special channels will be...
Read More
