Posted by admin on Jul 31, 2021 in |
Cancer initiates from the transformation of normal living cells into malignant cells via a multistage event that usually advances from a pre-cancerous phase to a malignant tumour. Anti-metastatic drugs or anti-neoplastic drugs prevent and regulate the growth of onco cells. Based on the mode of drugs, the universally anticancer drugs market is categorized into cytotoxic, targeted, and hormonal drugs. The targeted drugs class is further divided into monoclonal antibodies, tyrosine kinase inhibitors, and others. The worldwide anticancer drugs market falls into five regions: North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. Cancer is considered the second largest cause of death globally and is responsible for an estimated 9.6 million deaths in 2018. Globally, about 1 out of 6 deaths is due to cancer. Approximately 72% of deaths from cancer occur in developed and developing countries. Synthetic drugs and other modes of treatment are pre-existing. Chemotherapy treatments have its own limitations due to their toxic effects on non-targeted tissues and it further leads to health...
Read More
Posted by admin on Jul 31, 2021 in |
Euphorbia fusiformis Buch.-Ham.ex D. Don, (Synonym: Euphorbia acaulis Roxb) is an infrequent, medicinal, geophytic herb of the family Euphorbiaceae. It is distributed only in few pockets of India, Nepal, Africa and China. In India, it is found to grow in Maharashtra, Karnataka, Gujarat, Goa, Rajasthan, Andhra Pradesh, Madhya Pradesh, Uttar Pradesh, Bihar, Tamil Nadu and West Bengal. Traditionally, local tribal people of India had been using this plant to treat headache, arthritis, gout, paralysis, diarrhoea, abdominal diseases, abdominal tumor, liver disorders, urinary stones, chronic wound cracks, skin disease, eczema and poor lactation. In scorpion and snake bites, plant latex was used as an antidote. Phytochemical analysis of the plant demonstrated the presence of number of primary and secondary metabolites such as flavonoid, phenol, proteins, saponin, phytosterol, triterpenoids, fixed oil and fats. It also contains vitamin C, vitamin E, and minerals. Some of the important phytoconstituents found in roots of Euphorbia fusiformis are Caudicifolin, Ellagic acid, 3, 3′-di-O methylellagic acid and Euphol. Sesquiterpenes, aliphatic compounds and small amount of monoterpenes...
Read More
Posted by admin on Jul 31, 2021 in |
The medicinal plant Citrullus colocynthis is very significant for indigenous medicine. The pharmacological effects of root, fruits, seeds, leaves, and the whole C. colocynthis have been practices for the treatment of diseases. Phytochemical screening of the fruits of C. colocynthis has observed several bioactive compounds. The glycosides, flavonoids, alkaloids, carbohydrates, fatty acids, and essential oils contain phenolic and flavonoids in the C. colocynthis fruit. In current research work, a review on pharmacological study of medicinal plant C. colocynthis. Many related research articles were checked and collected in Google Scholar, PubMed, Science direct, the scientific information Database, and Scopus. For the present study purpose, using the terms colocynthis, Indrayan, Garhtumba, and Kharatumba in the title of all articles published to 2021 were observed. This study suggests that the extract of C. colocynthis could offer cheaper herbal drugs. The finding of the present research work would be significant, help prepare less costly, eco-friendly herbal drugs to treat various diseases and infections to replace synthetic...
Read More
Posted by admin on Jul 31, 2021 in |
Cancer is a serious health concern in both developed and developing nations. Cancer causes due to unwanted growth of cells and irregular cell division. Medicinal plants have been used by village folk from ancient times. The plants contain various bioactive compounds that can be used for treating cancer. Some of the phyto compounds isolated from plants have shown promising results; these include curcumin, vinblastine, vincristine, camptothecin. The various phytochemicals like terpenoid, flavonoids, and coumarins were also found promising in treating cancer. A lot of plants based compounds are under trial resulted in good responses. Around 17 different plant families, members with their active constituents reported for targeting cancer pathways were summarized. In this review, various medicinal plants which are reported for anticancer drug discovery were listed and mentioned for their mechanisms of action, such as CDK inhibitor, roles of apoptosis, and angiogenesis in cancer pathways. These plants are very useful in various research studies or for research purposes; these plants seek considerable...
Read More
Posted by admin on Jul 31, 2021 in |
Background: World Health Organization states that antibacterial/antimicrobial resistance (AMR) can threaten the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi. Objective: This review aims to discuss the plants and their derivatives having anti-corona virus/ viral activity. Methods: For the preparation of this review article, all the relevant information was gathered from accessible and inaccessible resources (Web, Books, Thesis, etc.). Results: It has been accepted worldwide that the uses of herbal products provide stronger immunity which helps to fight against these microbial species. SARS- CoV2 virus is now a pandemic, affecting many countries around the globe. This long series of herbal species may interfere with the target-specific proteins named S Protein, S protein- ACE-2 interaction, Helicase protein, N Protein, 3CLpr, PL pro to prevent the viral replication in the host. Traditional herbal medicine not only inhibits the virus attachment to the host body but also prevents replication and boosts up the host immune system. Natural remedies reduce the viral load and,...
Read More
