Posted by admin on May 31, 2021 in |
Prune is a dry form of plum fruit; its botanical name is Prunus domestica characterized by unique nutrients and dietary bioactive profile. Prunes have wide application in traditional medicine and are known for their beneficial role as a laxative in management of non-communicable diseases and bone health. Researches have proved their antioxidant, anticancer, antihyperglycemic, anti-hyperlipidemic, anti-osteoporosis properties. The available evidences were searched and summarized after an extensive search on review of published literature with a focus on exploring the therapeutic and pharmacological effects of prunes. A number of preferred databases were searched using the Pub Med database, Science Direct, SciELO, Google Scholar, Link Springer, and Research Gate. This review investigated the potential mechanisms and effects of dried plums on overall health; the chemical composition of prunes reflects the presence of polyphenols like chlorogenic acids, neochlorogenic acid, caffeic acid, coumaric acid, proanthocyanidins and some other similar compounds, which are beneficial for improving and maintaining health and wellbeing. Prunes are used for treatment of acid dyspepsia, nausea, vomiting, fevers, headaches. Prunes...
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Posted by admin on May 31, 2021 in |
Since 2019-November on world facing whole world is facing an unprecedented health problem. The WHO has said that a pandemic infection are coming with a new virus species of coronavirus is called SARS-CoV-2. Coronavirus 2019 is associated with global health and acute coronary respiratory syndrome coronavirus-2. COVID-19 is widely spread through drip channels. The virus causes mild symptoms in many who have manifested many symptoms, dry cough, fatigue, muscle aches and bruises; Common symptoms include diarrhea, colds, hemoptysis, sore throat and runny nose. Severe infections, which are the main treatment options for critical care patients, include severe lung burns, sepsis, ARDS and septicemia. Here we present nine key research questions related to virus infection, releasing anonymous, treatment, pre-symptomatic viruses, diagnosis, vaccine growth, origins of the virus and also viral infections, etiology, viral infections, clinical picture, treatment and infection. Effective treatment is not yet available. Every day there is an increase in morbidity and mortality, and adherence to the instructions of infection prevention and infection should control government organizations are...
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Posted by admin on May 31, 2021 in |
Next-generation printing or commonly known as three-dimensional (3D) printing (3DP), is a fabrication process of construction of a 3D object using a computer-aided design or digital 3D model. The 3D object is created layer by layer by depositing, joining, or solidifying a feedstock material such as thermoplastic polymer under the control of a computer-designed program. It is considered the latest technology that has the potential to address complex medical and pharmaceutical problems, such as prototyping essential medical devices, equipment, and novel drug delivery systems. The ability of 3DP to produce medications with accurate specifications tailored to the needs of individual patients has indicated the possibility of developing personalized medicines. The technology allows dosage forms to be precisely printed in various shapes, sizes, and textures, in a limited time period. In spite of many potential medical and economic benefits of 3DP, some technical and regulatory challenges are associated with the widespread application of 3DPin the pharmaceutical sector; those need to be addressed by proper research so that the benefit of...
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Posted by admin on May 31, 2021 in |
Coronavirus disease (COVID-19), an infectious disease caused by a novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection began in bats and was communicated to people through yet obscure go-between creatures in Wuhan, Hubei territory, China, in December 2019. Its outbreak threatened the lives of many people throughout the world. There is no distinct treatment available yet, and is an urgent need to treat, prevent and eradicate this virus. Recently, numerous new technologies have been explored for the diagnosis, prevention, and treatment of viral infections. Among these, nanotechnology has emerged as a promising antiviral treatment, and currently, the development of COVID-19 drug delivery involving nanotechnology is under investigation. This review aimed towards the prospective treatment options integrating the ever-expanding field of nanotechnology against COVID-19. We focused on the current scenario in the developments of nanotechnology-based approaches because of the ongoing pandemic of COVID-19, the effectiveness of nanomaterials as vaccines, nanosensors as diagnostic or antiviral tools against coronaviruses, and post COVID-19 era has been discussed...
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Posted by admin on May 31, 2021 in |
Oral Conventional dosage forms offer no control over the release of drug from the dosage form, which leads to variations in plasma drug levels; gastric emptying and gastric resident time are two another important factors that have a significant effect on the therapeutic efficacy of drug and it causes changes in the retention time of the drug. Accordingly, Floating microspheres is one of the most dependable and inventive techniques among all the gastro retentive drug delivery systems to overcome from these problems. Floating microspheres are mainly obtaining importance because of their vast suitability in the targeting of drugs to the stomach, undergo action and scattered uniformly over the gastric fluid to avoid the changes of gastric emptying and enlarge the liberation of the drug. This system also allows vastly in the fabrication of new controlled and delayed-release oral formulations, thus Expanding revolutions in pharmaceutical Expansion. The present review, in brief, says the physiology of the Intestinal gastric tract and elements governs the gastro retentive drug delivery system. This review...
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