Posted by admin on May 31, 2021 in |
Next-generation printing or commonly known as three-dimensional (3D) printing (3DP), is a fabrication process of construction of a 3D object using a computer-aided design or digital 3D model. The 3D object is created layer by layer by depositing, joining, or solidifying a feedstock material such as thermoplastic polymer under the control of a computer-designed program. It is considered the latest technology that has the potential to address complex medical and pharmaceutical problems, such as prototyping essential medical devices, equipment, and novel drug delivery systems. The ability of 3DP to produce medications with accurate specifications tailored to the needs of individual patients has indicated the possibility of developing personalized medicines. The technology allows dosage forms to be precisely printed in various shapes, sizes, and textures, in a limited time period. In spite of many potential medical and economic benefits of 3DP, some technical and regulatory challenges are associated with the widespread application of 3DPin the pharmaceutical sector; those need to be addressed by proper research so that the benefit of...
Read More
Posted by admin on May 31, 2021 in |
Coronavirus disease (COVID-19), an infectious disease caused by a novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection began in bats and was communicated to people through yet obscure go-between creatures in Wuhan, Hubei territory, China, in December 2019. Its outbreak threatened the lives of many people throughout the world. There is no distinct treatment available yet, and is an urgent need to treat, prevent and eradicate this virus. Recently, numerous new technologies have been explored for the diagnosis, prevention, and treatment of viral infections. Among these, nanotechnology has emerged as a promising antiviral treatment, and currently, the development of COVID-19 drug delivery involving nanotechnology is under investigation. This review aimed towards the prospective treatment options integrating the ever-expanding field of nanotechnology against COVID-19. We focused on the current scenario in the developments of nanotechnology-based approaches because of the ongoing pandemic of COVID-19, the effectiveness of nanomaterials as vaccines, nanosensors as diagnostic or antiviral tools against coronaviruses, and post COVID-19 era has been discussed...
Read More
Posted by admin on May 31, 2021 in |
Oral Conventional dosage forms offer no control over the release of drug from the dosage form, which leads to variations in plasma drug levels; gastric emptying and gastric resident time are two another important factors that have a significant effect on the therapeutic efficacy of drug and it causes changes in the retention time of the drug. Accordingly, Floating microspheres is one of the most dependable and inventive techniques among all the gastro retentive drug delivery systems to overcome from these problems. Floating microspheres are mainly obtaining importance because of their vast suitability in the targeting of drugs to the stomach, undergo action and scattered uniformly over the gastric fluid to avoid the changes of gastric emptying and enlarge the liberation of the drug. This system also allows vastly in the fabrication of new controlled and delayed-release oral formulations, thus Expanding revolutions in pharmaceutical Expansion. The present review, in brief, says the physiology of the Intestinal gastric tract and elements governs the gastro retentive drug delivery system. This review...
Read More
Posted by admin on May 31, 2021 in |
Though the anesthesia-related death of a 15-year-old Hannah Greener marked the beginning of pharmacovigilance 160 years ago, the science of pharmacovigilance was not established as a separate field until the wake of the thalidomide tragedy in 1960’s. The World Health Organization (WHO) instituted International Drug Monitoring Program to internationalize the act of drug safety monitoring. Inspite of this, many countries, particularly the low and middle-income developing countries, found it difficult to implement a robust drug safety monitoring system in their country due to various technical and financial snags. India was able to establish its own pharmacovigilance system called Pharmacovigilance Program of India (PVPI) only in 2005. This article analyzes the hurdles and challenges faced by India during the implementation phase of the Pharmacovigilance program, and this article also compares the pharmacovigilance system of India with few other developed and developing...
Read More
Posted by admin on May 31, 2021 in |
Diabetes mellitus is one of the most prevalent metabolic disorders and has been a leading cause of death in the last few decades. Oral hypoglycaemic agents are mostly used in the treatment of diabetes, but the main drawback of these agents is that they have some unavoidable side effects. Nowadays, researchers are mainly focusing on unexposed medicinal plant species as an alternative source for the treatment of diabetic mellitus. This review article aims to compile all the reported antidiabetic plants used by ethnic people of Assam as a folk remedy to cure diabetes mellitus and help the researcher investigate unexposed antidiabetic medicinal plants. In this concern, an extensive literature survey was carried out through different books and electronic search engines to understand the cause of diabetes mellitus and their traditional herbal remedy. Here listed 92 plant species belong to 45 families that claim ethnomedical indication to treat various diabetes mellitus. The roots, rhizomes, stems, leaves, barks, bulbs, flowers, and even the whole plant are utilized as folk remedies to...
Read More
