Posted by admin on Oct 31, 2020 in |
Psoriasis is a chronic inflammatory disease that affects about 1-2% population. It is caused by different factors, the most common cause being genetic predisposition. Other causes or factors that can trigger psoriasis include infection, physical trauma to the skin, stress and certain medication, for example, beta-blockers and antimalarials. People suffering from psoriasis are at a greater risk of developing psoriatic arthritis, anxiety, depression, and cardiovascular diseases. Psoriasis can affect the quality of life of the patients and can result in financial problems as repeated treatment is required. Nowadays, people now opt to make use of natural remedies alone or in conjunction with conventional therapy to improve their condition. In this review article, natural remedies that have proved to have antipsoriatic activity have been summarized. These natural sources can be a source of bioactive compounds that have a potential to treat and manage...
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Posted by admin on Oct 31, 2020 in |
The mitogenic activity in earthworms should be accompanied by antioxidative and antimicrobial activities during the healing or regeneration of their amputated part. These activities are achieved by bioactive macromolecules in their tissue and coelomic fluid. The antioxidative activity applied to prevent the cellular function from oxidative damage and assist cell multiplication. The antimicrobial activity prevents the wounded area from bacterial infection and enhances cell division. This review aims to promote cheap natural products of earthworms to be used widely in human medicine. Thus, we reviewed how to extract coelomic fluid, preparation of tissue homogenate (G-90) and application of mitogenic, antioxidative, antimicrobial activities on experimental animal rats, mice and rabbits. These products were efficient for hasty wound healing, the proliferation of damaged bone, boosting of immune cells and nerve cell regeneration without carcinogenic and mutagenic characteristics. Therefore, the biotechnological application of tissue homogenates and coelomic fluid should get due...
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Posted by admin on Oct 31, 2020 in |
To study various types of the benign cyst, differential diagnosis, diagnosis for identification of cyst, suitable treatment options based on various types of cysts that are occurring in the ovaries. An ovarian cyst is a commonly occurring mass in reproductive-age women. Functional ovarian cysts are physiologic and usually dissolve spontaneously within a couple of menstrual cycles. A combination of oral contraceptives can be used to prevent the occurrence of these cysts. The scope of this review is to focus on the types, causes, and treatment options of benign ovarian cyst in the fertile women. Ovarian cysts are a commonly occurring condition in women nowadays. The differential diagnosis includes functional cysts, dermoid cysts, endometrioma, and another confirmatory diagnosis such as ultrasonography are used to know the type and size of the occurring mass in the ovaries. A suitable evaluation includes a medical history and physical examination, laboratory tests, and other imaging modalities. The treatment options include conservative follow-ups, medical treatment with the help of pills, and lastly, surgery depending upon...
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Posted by admin on Oct 31, 2020 in |
“Nanotechnology” is a science which deals with the particles less than the size of 100 nm. Materials at the atomic and molecular scales are engineered and manufactured by this technology. The use of nanotechnology for “phytotherapy” or treatment of various diseases by herbal medicines/drugs, including herbal drug delivery, where current and emerging nanotechnologies could enable entirely novel classes of therapeutics, has been reported. The researchers have succeeded in using nanotechnology to insert and simultaneously activate the genes delivered into plant cell walls. The nanomaterials can significantly enhance the pharmacokinetics and therapeutic index of plant origin drugs. Interestingly, pharmaceutical sciences are using nanoparticles to reduce toxicity and side effects of drugs. Herbs and herbal derivatives are of great research interest owing to their wide applications in therapeutics. Several folk evidence has been recorded in the formulations of the ancient world’s medicinal system, which have attracted researchers for their scientific validation. Various herbal compounds have been identified and showed their therapeutic efficiency against pathophysiological conditions. Employing these herbal compounds for synthesizing...
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Posted by admin on Oct 31, 2020 in |
As we understand that for achieving a supportive effect in the human body, the prescription should be bioavailable, and in this way, it depends upon the dissolvability of the drug. Starting late 40% of the meds are inadequate water dissolvable, which produces responses, for instance, gastric exacerbation, peptic ulceration, etc. An oral course of medication organization is the most favored defeat of conveyance, as it is helpful and simplicity of ingestion. One of the hindrances of this defeat is low bioavailability, as a large portion of the medications have poor solvency in water. On account of ineffectively water-solvent medications (BCS Class II), disintegration is the rate-restricting advance during the time spent medication assimilation. The purpose of this review is to highlight & improve the solubilization and bioavailability of insufficiently dissolvable sedates by using various approaches like physical, invention, and other changes or systems and included BCS course of action, transporters for dissolvability. Update and different techniques for dissolvability...
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