Posted by admin on Oct 31, 2018 in |
Encapsulation of thymol is important for its volatile nature, taste, and antispasmodic, antioxidant, antimicrobial, anticancer and anti-inflammatory properties. This review provides a summary of thymol encapsulation in different biodegradable polymers along with the methods of encapsulation and control release in various parts of the body. Biodegradability of shell material along with its health compatibility and the half life of the core material and knowledge of microstructure are some of the main issues that must be addressed while studying encapsulation of Pharmaceutically Active Ingredients (PAI). Different biodegradable polymers used for the encapsulation of thymol are xanthum gum, poly vinyl alcohol (PVA), gelatine, starch, sodium alginate and ethyl cellulose. Preparative conditions, such as concentration ratios, temperature, stirring speed, and nature of solvent used, have deterministic effect on the polymer shell formed around the core material. Purposes for encapsulation of PAI may be numerous, such as controlled release, targeted controlled release, protection/preservation, economic utilization, convenient packaging, and clever option for storage, easy portability and formulation, modification/ hiding undesirable property such as taste,...
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Posted by admin on Oct 31, 2018 in |
Pluronic lecithin organogels (PLOs) are thermo-dynamically stable, biocompatible, viscoelastic with improve drug permeation and localised action. PLOs have gained much popularity compared with other traditional topical and transdermal drug delivery system owing to their lower cost, flexibility of dose and longer contact time. PLOs enhances the permeability of drugs because of desired drug partitioning, modification of skin barrier system by its components and biphasic drug solubility that is it enhanced solubility of poorly soluble drugs and increased penetrability of hydrophilic drugs. In this review we discuss the insights of PLOs as topical and transdermal drug delivery...
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Posted by admin on Oct 31, 2018 in |
Diabetes mellitus is a widespread epidemic caused by insulin deficiency, decreased secretion, or both of them. This disease is one of the common metabolic disorders that affects 8.2% of the world population and is expected to reach 4.5% in 2025. More than 200 species of plants have anti-diabetic properties, but the mechanism of their effect is not well defined. Most herbs that have anti-diabetic properties include to the family of Leguminoaceae, Lamiaceae, Liliaceae, Cucurbitaceae, Asteraceae, Moraceae, Rosaceae and Araliaceae. The antidiabetic activities of medicinal plants are attributed to the presence of polyphenols, flavonoids, terpenoids, coumarins and and other constituents which show reduction in blood glucose levels. Searching among the different literature resources and various database and in view of the above aspects, the present article provides a comprehensive review on the available antidiabetic salvia species that have been approved by pharmacological and clinical evaluations, and whose mechanism(s) of action is assured. Numerous mechanisms of actions have been proposed for Salvia species extracts. Some hypotheses relate to their effects on...
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Posted by admin on Oct 31, 2018 in |
Background: Healthcare requirements have changed gradually from the primitive ages to this modern era. Information and communication technology has opened innovative techniques like home healthcare for patients through telehealth use. Aims: 1. To find out the usefulness and effectiveness of telehealth intervention on the daily living activities amongst children with disability in Saudi Arabia. 2. To find out the active engagement and self-management strategies that telehealth can provide for children with disability in Saudi Arabia. Methods: A literature review of 42 articles published in various databases was assessed. The articles having good scientific quality and explaining the usefulness and effectiveness of telehealth intervention on the daily living activities amongst children with disability were included. Results and Discussion: It is currently estimated that 3.73% of the population have functional disabilities which limit their independence. To address the disability issues, one must make use of the present information around the disability prevalence. The criterion for achieving a suitable balance of accommodation and support is a comprehensive assessment of the features of...
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Posted by admin on Sep 30, 2018 in |
Black pepper, the ‘King of spices’ (Piper nigrum L.), is a widely used spice, known for its pungent odour. From time immemorial, plant sources were used in traditional systems of medicine and day-to-day common use, such as in meal preparation and cosmetic purposes. This is due to their vast pharmacological potential with minimum side effects. Among the various species of the Piperaceae family, black pepper is one of the most popular due to its principle pharmacological component, piperine. Which is an alkaloid that has diverse pharmacological activities like antioxidant, anti-obesity, antitumor, antipyretic, anticonvulsant, anti-thyroid, antifungal, antibacterial, insecticidal, hepatoprotective, anti-asthmatic, larvicidal, antihypertensive, anti-inflammatory, antidiabetic, antidiarrheal, bio-availability enhancer, immunomodulator, antiepileptic, antifertility, GI stimulant, lipid metabolism accelerator, anticancer, CNS stimulant, diuretic, aphrodisiac, blood purifier and antiplatelet activities, etc. Due to some religious value of black pepper, its being popular from ancient time to modern generation. This review is aimed to provide a literature review on recent advancement of chemistry, pharmacognosy, pharmacological activities, new piperine based formulations and other general use of Piper...
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