Posted by admin on Dec 31, 2024 in |
Hyperpigmentation is a skin complaint where black patches or spots appear on skin. It affects a large percentage of the human population. Cosmetics that naturally lighten the skin have been shown to be both safe and effective for treating hyperpigmentation. To achieve a lighter skin appearance, skin lightening goods are commercially accessible for cosmetic resolutions. They’re also utilised in the clinic to treat pigmentary disorders like melasma and post-inflammatory hyperpigmentation. Various stages of melanin content in the skin are affected by whitening agents. The finding demonstrates that numerous bioactive substances have anti-oxidant and anti-inflammatory properties in addition to tyrosinase inhibition, melanosome transfer inhibition, and other mechanisms that affect the melanin production pathway. Many of them have been identified as good inhibitors of tyrosinase, a central enzyme in the process of melanogenesis. Others stop this enzyme from maturing or from transporting pigment granules (melanosomes) from melanocytes to keratinocytes. We present an overview of whitening products obtained from natural sources that may reduce skin pigmentation by interfering with pigmentary processes in...
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Posted by admin on Dec 31, 2024 in |
The aim of this paper is to give a systematic overview on the morphology, ethnobotanical uses, phytochemistry and pharmacological activities of Anogeissus latifolia. It focuses to identify the research gap and further proceed to experimental studies. It may also help out the researcher for further detailed studies. A systematic search criterion of literature was carried out by computing Google scholar, Pub med, NCBI, open access peer reviewed journals and web of science including some unpublished sources. The plant is known to possess wide range of pharmacological activities like Anthelmintic, Thrombolytic, Antiasthmatic, Anticonvulsant, Anticancer, Antidiabetic, Antibacterial, Antipyretic, Antioxidant, Antiulcer, Analgesic, Anti-inflammatory, Hepatoprotective and Wound healing activity. Limited numbers of phytoconstituents were reported like tannins, triterpenoids, ellagic acid, monosaccharides, β- sitosterol from the plant that shows biological activities with diverse ethnobotanical uses. The present review also explores the traditional medicinal uses of the tree, highlighting its role in treating various ailments and wide use of its gum in pharmaceuticals, food processing and...
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Posted by admin on Dec 31, 2024 in |
Grafting polymerization is a process in which polymer chains are covalently bonded (grafted) onto a backbone polymer, leading to the formation of a new material with enhanced properties or functionalities. This process involves the attachment of polymer chains (known as “graft chains” or “grafts”) onto the surface or within the bulk of the substrate material. Polysaccharides have numerous applications in various industries, including food, pharmaceuticals, cosmetics, and biotechnology. They are used as thickeners, stabilizers, emulsifiers, gelling agents, and drug delivery systems due to their biocompatibility, biodegradability, and functional properties. Flavonoids are a group of polyphenolic secondary metabolites found in plants, fruits, and vegetables. They show a wide range of health benefits. They have gained interest recently due to their possible benefits for human health, especially their antioxidant, antiviral, antiallergic, anti-inflammatory, and anticancer characteristics. Flavonoid-grafted polysaccharide-form complexes generate synergistic effects, such as enhanced physical, chemical, and functional properties. Therefore, they show great potential for applications in food, cosmetics, and medicine. Structural characterization methods of the graft products, including FTIR, NMR,...
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Posted by admin on Dec 31, 2024 in |
Lung cancer (LC) represents a significant global contributor to mortality, particularly for those between the ages of 40 and 50. Additional evidence for this predicament comes from the yearly rise in new LC cases and the disease’s dismal 5-year survival rate of fewer than 15%. Even though smoking has been linked to a significant portion of Lung Cancer cases, a sizable number of non-smokers also contract the condition, raising the possibility that LC development may have hereditary and epigenetic roots. The genome only has about 1% of coding regions. As a result, scientists have studied the genome’s noncoding region and discovered that noncoding RNAs are crucial to the etiology of lung cancer. In more detail, lncRNAs and miRNAs have been extensively investigated over several decades of research. The function of miRNAs in post-transcriptional gene regulation is widely known and understood. It has also been demonstrated that the antagonistic interaction between lncRNAs and miRNAs further regulates gene expression in both healthy and disease situations, including Lung Cancer. A circular RNAs...
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Posted by admin on Dec 31, 2024 in |
Concentrated preparations called extracts are made from raw materials by isolating specific components through specific methods. Essential oils, tinctures, liquid extracts, and dry extracts are among the different kinds of extracts. The type of input material, the solvent employed, the temperature, and the extraction time are all important variables. Efficiently isolating and condensing particular ingredients for use in tastes, perfumes, and medicinal applications is the aim of extraction. A Soxhlet system can be used to manufacture dill seed oil through continuous solvent extraction. The right solvent must be used for this procedure; ideally, it should be able to dissolve the targeted compounds without causing any degradation. In order to extract the oil, the Soxhlet extraction cycle involves heating the solvent, letting it evaporate and condense, and then repeatedly washing the raw material. Requirements for scaling up Soxhlet extraction include preserving steady-state mass and energy balances. While the energy balance takes into consideration the heat input and thermal losses during the process, the mass balance makes sure that the amounts...
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