Posted by admin on Nov 1, 2013 in |
Gold nanoparticles (AuNPs) have appeared as an attractive candidate for delivery of various drug molecules or considered as extraordinary molecular carriers for the targeting, intracellular trafficking and delivery of a huge array of biomolecules including DNA, RNA, proteins, peptides, drugs, genes and other molecules of therapeutic significance. Particularly gold nanoparticles have attracted intensive interest, because they are easily prepared, have low toxicity and can be readily attached to molecules of biological interest. More and more research shows that AuNPs-based technologies are becoming promising approaches in drug and gene delivery, liver targeting, brain targeting, cancer research and AIDS treatment. The present review focuses on synthesis and functionalization methods of GNPs, the past researchs and reviews about GNPs, their emerging applications and uses and their future...
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Posted by admin on Oct 1, 2013 in |
Plants have always provided an important source of medicines. They may be used by natives in folk medicine and later adopted by conventional western medicine as their efficacy was confirmed. Any pharmacological modification caused by herbal substances to another prescription medication (diagnostic, therapeutic or other action of a drug) in or on the body. An herb might increases or decreases the effects of co-administered drugs. Consequences can be beneficial, undesirable or harmful effects. Interactions between herbs and drugs may increase or decrease the pharmacological or toxicological effects of either component. Synergistic therapeutic effects may complicate the dosing of long-term medications eg: Herbs traditionally used to decrease glucose concentrations in diabetes-I could theoretically precipitate hypoglycemia if taken in combination with conventional drugs. Herbal medicines are ubiquitous: the dearth of reports of adverse events and interactions probably reflects a combination of underreporting and the benign nature of most herbs used. This article provides brief idea about pharmacist can change the present scenario and utilize their knowledge in providing health information about...
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Posted by admin on Oct 1, 2013 in |
Worldwide, cardiac disorders constitute a leading cause of morbidity and mortality. Cardiac disorders include high blood pressure, atherosclerosis, arrhythmia, congestive heart failure, stroke etc. Increase in incidence of cardiac disorders is a manifestation of lifestyle changes. Although modern drugs are effective in preventing the cardiac disorders, their use is often limited because of their side effects and adverse reactions. Use of herbal drugs is not only cost effective but also has better safety and efficacy. The World health Organisation (WHO) estimates that about 80% of the population living in the developing countries still relies on herbal drugs for their primary healthcare needs. Today, ethno-botanical and ethno-pharmacological studies of medicinal plants continue to attract investigators for research work globally. Aim of this current review to explain herbal phytoconstituents therapy on the basis-“Type of disorder, Mode of action and Pharmacological screening model”, which could be an informatics approach in management of cardiac...
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Posted by admin on Oct 1, 2013 in |
Herbal extracts are primarily added to the cosmetic formulations due to several associated properties such as antioxidant, anti inflammatory, antiseptic and antimicrobial properties. Even today, people in rural and urban areas depend upon herbs for traditional cosmetics. Information on the herbal cosmetics was collected via electronic search (using pub med, scifinder, Google Scholar and web of science) and library search for articles published in peer-reviewed journals. Furthermore, information also was obtained from some local books on ethnopharmacology. The herbal extracts, as a whole or part, have been used for various ailments of the skin, hair, and dental care for overall appearance. Cosmetics alone are not sufficient to take care of skin and others body parts, it requires association of active ingredients to check the damage and ageing of the skin. Herbal cosmetics have gained much popularity among the population. Herbal cosmetics products claimed to have efficacy and intrinsic acceptability due to routine use in daily life and avoid the side effects which are commonly seen in synthetic products. Due...
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Posted by admin on Oct 1, 2013 in |
Phenolic compounds are group of molecules which contain different families of secondary metabolites. Phenolic compounds, secondary metabolites, are abundantly found in plants and are mostly categorized into two major groups: non-soluble compounds and soluble compounds. Stilbenes which come under the category of soluble compounds of phenolics are small molecules, ranges in their weight from ~200 to 300 g/mol and are found in diverse plants. These compounds are produced in plants via phenylpropanoid pathway. Under unfavourable conditions such as microbial or viral attack, ultraviolet light exposure and disease in plants, stilbenes are synthesized and act as natural agents to protect plants. Piceatannol, a natural stilbene, is found in different plant species and is beneficial for human health. It possesses various pharmacological properties such as antioxidant, antitumor, anti-inflammatory and anti-carcinogenic activities. This review paper focuses on piceatannol, its sources, chemical synthesis mechanism, production and its useful applications in various...
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