Posted by admin on Jan 31, 2025 in |
Microbiota, in simple terms means the community of microorganisms, whereas microbiome means the whole genomes of the microorganisms in a particular environment. We humans consist of a large microbiome within as well as on body, most in the gut. The gut microbiota in human plays significant role in different aspects such as in human metabolism, nutrition, physiology, immune function, and various other body functions. The microbiota of human gut is mainly composed of strict anaerobes, outnumbering the facultative anaerobes. Evidence from various studies across the globe has reported that autistic people carry an altered gut microbiota in comparison to normal people, influencing the immune system thus establishing an relation between dysbiotic gut microbiota with autism. Moreover, as far as antibiotics are concerned, their irrigational use bedsides having the association with antimicrobial resistance are also associated with the autism spectrum disorder development when used in pregnancy and early childhood as reported by studies. Keeping the objective in mind, this review was written to highlight the present existing knowledge regarding gut...
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Posted by admin on Jan 31, 2025 in |
Introduction: Being an Oleaceae family member, Nyctanthes arbor-tristis, known as Night jasmine or Harashingar, is a legendary plant with enormous therapeutic potential. Research on the different plant parts, such as the leaf, flower, fruit, seed, and bark revealed the phytochemicals that were responsible for the primary pharmacological activities. These phytochemicals included glucose, oleanic acid, glycosides, carotene, tannic acid, flavanoids, benzoic acid, and essential oils. The present article discusses the taxonomy, vernacular names, distribution, botanical description, habitat, cultivation and propagation, traditional uses, phytoconstituents, and pharmacological activities of the plant. The article also describes the study carried out on the characterization of microscopy of the stem transverse section. Objective of the Study: To investigate the microscopic characterization of the stem of Nyctanthes arbor-tristis. Method: The thin transverse section of the plant stem was treated with several chemicals like alcohol (10%, 30%, 50%, 90%, 100%) and with xylene (10%, 30%, 50%, 90%, 100%). The dyes, saffranine, and methylene blue were used to stain the stem sections. DPX assisted in making a permanent...
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Posted by admin on Jan 31, 2025 in |
Aim: This study aimed to evaluate the efficacy and safety profile of DPP-4 inhibitors as add-on therapy in patients with type 2 diabetes. The study is important because DPP-4 inhibitors have been widely prescribed, and understanding their comprehensive effects is essential for better patient outcomes. Methods: An extensive literature search has been conducted using multiple databases, such as PubMed, Cochrane Library, Scopus, Web of Science, and Google Scholar. All results have been analyzed based on inclusion and exclusion criteria, and their findings are displayed statistically to ensure accurate comparisons between treatment groups. Results: DPP-4 inhibitors demonstrate significant efficacy in managing type 2 diabetes mellitus (T2DM), leading to a reduction in glycated hemoglobin (HbA1c) levels by 0.9% (9 mmol/mol; p < 0.0001) and fasting blood glucose (FBG) by 1.15 mmol/L (19.82 mg/dL; p = 0.001) among a cohort of 105 individuals. Notably, sitagliptin exhibited a remarkable HbA1c reduction of 1.66% (19 mmol/mol; p < 0.0001). These inhibitors also significantly curtailed glycemic variability, as evidenced by a mean amplitude of glycemic...
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Posted by admin on Jan 31, 2025 in |
Plant foods are wasted especially in millets as they are not required in that particular product processing. From the cultivation of millet to its processing and consumption of the final product, a significant amount of waste is generated. Wasted foods are not spoilt foods and still have the potential to be used for the second time as food. But unfortunately, the fate of waste is always landfills which surely create a menace. By this we are throwing nutria rich foods on one hand and on the hidden hunger is on the rise. The challenge that lies in front is converting this waste into a nutria rich and nutraceutical food again/ specialty ingredient for functional foods or super foods but should ensure zero waste this time. Millet has gained momentum and rejuvenated in the recent past. Even then millets for its part is also contributing to waste generation that needs attention. (No of words...
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Posted by admin on Jan 31, 2025 in |
The advancement and changes in the pharmaceutical and cosmetic industry are governed utilizing the interests of clients for biologically energetic elements obtained naturally in place of synthetic manufacture and resources. One such novel technique within the beauty enterprise is using marine life as a supply of active components like micro and macroalgae, sea corals, marine bacteria, and seaweeds as shown in within the manufacture of skin care products. Marine organisms are discovered in intense conditions or habitats and have evolved with positive beneficial homes that terrestrial organisms lack. Those traits include antioxidant, anti-wrinkling, rehydrating, skin lightening, beautifying, emollient, solar-screening, moisturizing, firming and supplying smooth texture, and shielding the pores and skin. This biodiversity from the oceans has shown amazing results and affected person compliance in the fields of cosmetology and pharmacy. Not only in cosmetics but marine based products obtained from the vast expanse of our oceans, covering 70 percent of the globe, has served as a cradle for human civilization. Thalassotherapy encompasses a diverse range of treatments, including...
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