Posted by admin on Jul 31, 2024 in |
Chemotherapy-induced neutropenia (CIN) is a common and sometimes fatal side effect of treatment for acute lymphoblastic leukemia (ALL), the most common malignancy in individuals over 40. Antibiotics are used in addition to supportive care as a current treatment. Granulocyte-colony stimulating factor (G-CSF) has been tested in clinical studies as a supplementary treatment to reduce febrile neutropenia in children with ALL. Regarding cancer therapy, the grade and timing of CIN may have predictive and prognostic effects. The following factors are linked to CIN: advanced age, low nutritional and functional status, a history of major comorbidities, the disease’s stage, particular chemotherapy regimens, and combination therapies. The management of CIN in ALL is fraught with difficulties, such as the lack of a consensus nomogram for the risk assessment of febrile neutropenia and uncertain genetic risk factors. The advantages of treating FN with granulocyte colony-stimulating factor and the best course of antibiotics in an emergency must be clarified. The purpose of the review was to explore the function of G-CSF in the management of CIN in ALL...
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Posted by admin on Jul 31, 2024 in |
Clitoria ternatea (Blue tea) is a traditional medicinal plant belonging to family Fabaceae having generous amount of anthocyanins which possess majorly antioxidant properties. It contains wide range of phytoconstituents such as triterpenoids, flavanol glycosides, tannins, alkaloids, amino acids, proteins, ternatins (poly acylated anthocyanins) and carbohydrates etc. According to the data obtained from different in-vitro studies, this plant possess antioxidant, antimicrobial, antidiabetic, hepatoprotective, nootropic, central cholinergic, antidepressant, antianxiety, anticonvulsant, anti-inflammatory, analgesic, antipyretic, wound healing, anticancer and many other pharmacological properties. In this report various preclinical studies data revealed about the efficacy of Clitoria ternatea plant in the treatment of neurological, inflammatory and oxidative stress induced...
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Posted by admin on Jul 31, 2024 in |
Biochar can be used as an efficient and low-cost adsorbent for wastewater treatment as heavy metal pollution has become the serious issue for environmental pollution today. A number of studies have demonstrated effective removal of heavy metals from water by biochar. Several factors affecting the sorption tendency of biochar, feedstocks materials play a significant role. Depending on the biochar type, heavy metals can be removed by different methods such as complexation, physical sorption, precipitation and electrostatic interactions. In recent years, ample method for heavy metal removal from wastewater has been extensively studied. This paper reviews the recent methods that have been used to treat heavy metal removal from wastewater and evaluates these techniques. These techniques include ion-exchange capacity, adsorption, membrane filtration, coagulation-flocculation, flotation and electrochemical methods. From literature review it is evident that ion-exchange, adsorption and membrane filtration are the most recent studied for the treatment of heavy metal...
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Posted by admin on Jul 31, 2024 in |
“Costus igneus,” popularly known as the “insulin plant,” is a herb that has been used for medicinal purposes in Southeast Asia since ancient times. It is just recently that the plant was imported to India, and in the southern region of the country, it is being grown as an appealing plant. In addition to other phytochemicals, the insulin plant contains elements such as steroids, alkaloids, flavonoids, triterpenes, glycosides, and saponins. Diabetes mellitus is being treated using the leaves of this plant by incorporating them into the diet of the patient. “A leaf a day keeps diabetes away” is the mantra that the plant has adopted. A wide variety of pharmacological effects can be observed, including those that are anti-inflammatory, anti-proliferative, antibacterial, anti-urolithiasis, and anti-diabetic, amongst others. Therefore, the purpose of this review study is to evaluate the many medicinal characteristics of the “insulin plant,” also known as Costus igneus, to make it possible for it to be utilized in future research and to assist...
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Posted by admin on Jul 31, 2024 in |
Systemic fungal infections, including opportunistic and endemic mycoses, pose a significant threat to immunocompromised individuals. Mucormycosis, caused by zygomycetes, is particularly devastating, characterized by tissue necrosis and diverse clinical manifestations. Risk factors such as immunodeficiency and underlying diseases contribute to its incidence. Through a comprehensive literature analysis, this review examines existing data on mucormycosis biomarkers. Treatment typically involves aggressive antifungal therapy and surgical debridement. Promising biomarkers like galactomannan and mannan are identified for early detection and monitoring, crucial for improving diagnostic accuracy and facilitating timely interventions. Pursuing biomarkers for systemic mycoses is crucial for enhancing infection management. Early detection through biomarkers has the potential to decrease morbidity and mortality associated with mucormycosis, ultimately improving outcomes for vulnerable...
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