Posted by admin on Nov 1, 2012 in |
A counterfeit medicine is one which is deliberately and fraudulently mislabeled with respect to identity or source. Counterfeiting apply to both branded and generic product which include products with the wrong ingredients, without active ingredients, with insufficient active ingredients. According to WHO, 25% of medicines consumed in poor countries could be counterfeit or below standard.An estimate suggests that these drugs are a $200 billion industry worldwide. India could be an easy target for counterfeits, as the manufacturing costs is 40% cheaper here as compared to other countries. Deputy drug controller general of India says, counterfeit medicines often resemble the originals in chemical composition, but he thinks the biggest problem is in the packaging. A committee set up by the Indian Ministry of Health has approved a proposal to put 2D bar codes and scratch-off labels on medicines. The user scratches off the cover and tests what is underneath to a free phone number, to find out if a pill is real. Quick Response (QR) codes are also being tested....
Read More
Posted by admin on Nov 1, 2012 in |
Self emulsifying is a topic of current interest for overcoming the formulation difficulties of drugs with poor aqueous solubility. SEDDS are isotropic mixture of oil, surfactant and co-surfactant with a unique ability to form fine oil-in-water (o/w) emulsions or micro emulsions upon mild agitation in the gastrointestinal tract which present the drug in a solubilized form, and the small size of formed droplet provides a large interfacial surface area for drug absorption. It is a promising strategy to improve the rate and extent of oral absorption. The SEDDS were characterized for robustness to dilution, globule size, polydispersity index and zeta...
Read More
Posted by admin on Nov 1, 2012 in |
Traditional analytical approaches including HPLC (High-Performance Liquid Chromatograph), GC (Gas Chromatograph), UV (Ultraviolet) detection, etc., have become insufficient to effectively handle the growing number of challenges in analyses of species- specificity and sensitivity. Modern analytical technique referred to as hyphenated techniques, originate from the traditional use of molecule or element specific detection in electrophoresis or chromatography. Currently the most common techniques for trace element speciation include a combination of separation technique coupled with a detection technique that is more sensitive. Earlier such hyphenated techniques were the coupling of separation of a special sample preparation off-line and later adding a detection technique. Presently, the hyphenated technique is developed from the coupling of a separation technique (Chromatography) and an on-line spectroscopic detection technology. Hyphenated techniques combine chromatographic and spectral methods to exploit the advantages of both. Chromatography produces pure or nearly pure fractions of chemical components in a mixture. Spectroscopy produces selective information for identification using standards or library spectra. These hyphenated techniques offer shorter analysis time, higher degree of automation,...
Read More
Posted by admin on Nov 1, 2012 in |
The phrase alternative therapy is used to explain a wide range of treatments which, generally, are not available from conventional doctors. It may be diverse for different diseases. The Alternative therapy focuses on the many things from diet to exercise and lifestyle. Many people suffering from disease are looking for the management of diseases with the help of alternative therapies. According to physicians, most of the alternative therapies started with clinical observation or scientific research. These therapies include yoga, aromatherapy, massage, hypnosis, biofeedback, herbal remedies and many others. The main advantage of these therapies is to treat the basic cause of disease and health related problems or to support the conventional therapies. Not only are the variety of alternative therapies measured to be safe and effective, they also deal individuals a wide variety of health therapy that simply do not exist through conventional treatment. This article focuses on different alternative therapies with their benefits in conventional therapies which can promise ultimate answers to treat the...
Read More
Posted by admin on Nov 1, 2012 in |
Standartizated plants extracts are new opportunity in addition with standard therapy. Hawthorn extract, Tribulus terrestris extract and magnesium gluconate are forming well balanced nutritional supplement that could benefits people with cardiovascular diseases and diabetes. All three substances are well known in the common herbal medicine in our country and abroad. Their mechanisms’ of actions is pointed in this review. Some pilot studies suggest recommended dosages for all of the three substances. Side effects and drug interactions are also considered, because they are serious problem not only to the common drugs but in herbal medicines too. Interesting fact is that in mouse models the dose dependence vasodilatation from hawthorn is not impaired by common medicine like: Diphenydramine, Propranolol, Verapamil and Glibenclamide. Another issue that we consider pregnancy and risk from this three particular extracts. Many data has shown that use of this kind of supplementation could be dangerous for the mother and the child, and our device in first place is “primum non nocere”. Magnisium gluconate proven to be beneficial...
Read More
