Posted by admin on Jan 1, 2012 in |
Cephalosporins are the most important type of antibiotics used vary widely. Analysis of these antibiotics is challenge because of their sensitivity and instability to different conditions. The present review is extended to find out different HPLC methods used for analysis for cephalosporins in formulations and biological fluids. The chromatographic conditions used for the analysis as well as analytical parameters study carried out with different experimental conditions and different combinations. During the study analytical parameters studied such as range, linearity, precision, accuracy, LOD, LOQ etc. The focus of study of analysis of cephalosporin in formulation and biological fluid are useful for the determination of various cephalosporin for budding...
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Posted by admin on Jan 1, 2012 in |
Vitamin A is an essential vitamin which is required in the vision process, epithelial maintenance, mucous secretion and reproduction obtained from carotenoids. Carotenoids have been considered to provide benefits in age-related diseases, against some forms of cancer (in especial lung cancer), strokes, macular degeneration, and cataracts. Till date, more than 600 carotenoids are known and 50 of them are consumed in meals to be transformed into the essential nutrient vitamin A. After their absorption, these carotenoids are metabolized by an oxidative rupture to retinal, retinoic acid and small quantities of breakdown products and are transported by plasma lipoproteins. Carotenes are mainly associated with low-density lipoproteins, while xanthophylls show a uniform distribution between the low- and high-density lipoproteins. The present review provides an insight into the recent status of pharmacological aspects of...
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Posted by admin on Jan 1, 2012 in |
Traditional remedies and preparation used for the treatment of skin, or the folk preparations used for healing skin diseases are known to be as Cosmeceuticals and cosmetics. The desire of gook looking and to be beautiful gave a huge market for the cosmetics. This is not a new tradition for human to look good; it has been a long ancient follow through for both the sexes to be presentable by beauty. For now, the desire of both the sexes to look younger than there age, to be fare and charming have directly increased the demand of herbal cosmetics as well as of the Cosmeceuticals in the market. The herbal formulations have been the first choice of the customers. For the reason of being less side effective and thought to be more potent than the synthetic formulations. There has been a long use of turmeric and sandalwood to be applied of face for fairness and freshness. As like many other herbs are used in daily life to be called as...
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Posted by admin on Jan 1, 2012 in |
Chromolaena odorata or siam weed is regarded as one of the most harmful weeds present on earth. Many efforts are being made for the control of this weed. But, none of them have provided any significant success. It has been utilized in the traditional medicinal systems for its curative properties for centuries. Some of the current studies have revealed its medicinal properties which have lead to an enhanced image of this plant as a medicinal herb. It showed anti-inflammatory, anti pyretic, analgesic, antimicrobial, cytotoxic and many other relevant medicinal properties in an appreciable...
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Posted by admin on Jan 1, 2012 in |
Oral route is the easiest and most convenient route of drug administration, being non invasive and cost effective, thereby leading worldwide drug delivery market. But major problem encountered in oral formulations (as estimated more than 50 % of oral formulations are found to be poorly aqueous soluble), is low bioavailability, giving rise to further problems like, high inter and intra subject variability, lack of dose uniformity and finally leading to therapeutic failure. The challenging task is to increase the bioavailability of drugs. Number of technological strategies are investigated and reported in literature for improving bioavailability like solid dispersions, cyclodextrins, micronization etc. But Self-microemulsifying Drug Delivery System (SMEDDS) have gained exposure for their ability to increase solubility and bioavailability of poorly aqueous soluble drugs with reduction in dose and also drugs are protected from hostile environment in gut. SMEDDS are isotropic mixture of oil, surfactant, drug and sometimes containing co-surfactant and administered orally which on mild agitation with GI fluids forms o/w microemulsion. This review gives complete overview of SMEDDS...
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