Posted by admin on Oct 1, 2010 in |
Eye is most unique organ of the body. Various drug delivery systems are used to deliver drug into eyes are used but there are various limitations of conventional systems so researchers are finding new ways by which contact time, bioavailability and residence time can be enhanced as well as patient discomfort and frequency of dose can be reduced. The conventional dosage forms are account for 90% of currently accessible ophthalmic formulations. The major problem encountered is rapid precorneal drug loss. To improve ocular drug bioavailability, there are significant efforts directed towards newer drug delivery systems for ophthalmic administration. Newer research in ophthalmic drug delivery systems is directed towards a combination of several drug delivery technologies, that includes to develop systems which is not only prolong the contact time of the vehicle at the ocular surface, but which at the same time slow down the elimination of the drug. In this review various new drug delivery systems applied in eye like inserts, in-situ gel, liposomes, niosomes, nanoparticles, iontophorosis, corneal shields,...
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Posted by admin on Oct 1, 2010 in |
Holistic living is an art of living in harmony with nature and deals with a concern for the whole universe. The term holistic medicine is derived from the term “Holism” which means that a living being is not to be viewed as a composite of different organs but as an integrated entity viewed as a whole. The holistic concept takes into account individual’s physical, spiritual, nutritional and even social background. Holistic medicine is an intelligent combination best utilizing both streams i.e. while mainstream medicine is well suited for crisis intervention and alternative medicine is for health maintenance. Alternative medicine denotes a system of health care where combinations of healthcare systems are used instead of conventional or mainstream medicine to treat diseases. Alternative medical practices are based on a belief system and are not derived from modern science. But holistic medicine neither rejects conventional medicines nor comprises alternative practices. It is high time to recognize the emerging awareness, need and practice of Holistic and Integrated medicine. Drawing from various systems...
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Posted by admin on Sep 15, 2010 in |
Niosomes are self assembled vesicles composed primarily of synthetic surfactants and cholesterol. They are analogous in structure to the more widely studied liposomes formed from biologically derived phospholipids. Niosomes represent an emerging class of novel vesicular systems. Niosome formation requires the presence of a particular class of amphiphile and aqueous solvent. In recent years a comprehensive research carried over niosome as a drug carrier. Various drugs are enlisted and tried in niosome surfactant vesicles. Niosomes proved to be a promising drug carrier and has potential to reduce the side effects of drugs and increased therapeutic effectiveness in various...
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Posted by admin on Sep 15, 2010 in |
Guava (Psidium guajava Linn.) Family Myrtaceae is important plant used traditionally for medicinal purposes. Guava is rich in antioxidants compounds and contains a high level of ascorbic acid. The pharmacological actions and the medicinal uses of aqueous extracts of guava leaves in folk medicine include the treatment of various type of gastrointestinal disturbances such as vomiting, diarrhea, inhibition of the peristaltic reflex, gastroenteritis, spasmolytic activity, dysentery, abdominal distention, flatulence and gastric pain. The important active constituents are essential oils, flavonoids, carotenoids, polyphenolic compounds, pentacyclic triterpenoids, esters, and aldehydes etc. This paper explains the Evidence-based information regarding the phytochemistry and pharmacological activity of this...
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Posted by admin on Sep 1, 2010 in |
Gastric hyperacidity and gastro duodenal ulcer is a very common global problem today. Among various causes of gastric ulceration lesions caused by stress, alcohol consumption, H.pylori infection and use of NSAIDs have been shown to be mediated largely through the generation of reactive oxygen species (ROS), especially hydroxyl radical (*OH). Hyper secretion of gastric acid is a pathological condition, which occurs due to uncontrolled secretion of hydrochloric acid from the parietal cells of gastric mucosa through the proton pumping H+ K+ ATPase. The modern approach to control gastric ulcer is to inhibit gastric acid secretion, to promote gastro protection, to block apoptosis and stimulate epithelial cell-proliferation for effective healing. On contrary most of the green pharmaceuticals reduces the offensive factors and have proved to be safe, clinically effective, better patient tolerance, relatively less expensive and globally...
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