Posted by admin on Mar 31, 2024 in |
Medical device, a device or instrument or apparatus or that is used to treat or prevent or diagnose or mitigate or cure the disease or to replace the structure of the body parts mimicking the natural function. The medical device sector started to grow rapidly in the last 8 years. Developed countries like the USA, European Union, and Japan concentrated on this sector to increase their production capability, and regulations were stringent to prevent unlawful happenings. India still lags in the development of the medical device sector. Earlier the rules and regulations for medical devices in India were followed the same as the drugs and cosmetics, which raised various questions regarding the regulatory process of medical devices. Very later the Medical Device Act 2017 was introduced which explained the manufacture, import, export & clinical investigation regulatory process required for a medical device. The Medical Device Act 2017 is framed as competent with the other national authority regulators and internal medical device regulator forums. This paper discusses the Medical Device...
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Posted by admin on Mar 31, 2024 in |
Inflammatory bowel disease (IBD) is a chronic inflammatory illness of the gastrointestinal tract that consists of Crohn’s disease and ulcerative colitis. The pathogenesis of IBD is multifactorial and involves a complex interplay between genetic, environmental, and immunological factors. A comprehensive literature search was conducted using relevant databases, such as PubMed, Scopus, and Web of Science. A tool such as PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) ensures that the review is conducted systematically and transparently. Alterations in gut microbial ecology are a hallmark of IBD and include decreased microbial diversity, an expansion of potentially harmful bacteria, and a loss of beneficial bacteria. These alterations are thought to contribute to the dysregulated immune response observed in IBD. The current understanding of the pathogenesis of IBD suggests that a dysregulated immune response to commensal bacteria in the gut plays a central role in the development and progression of the disease. Alterations in gut microbial ecology are a hallmark of IBD and include decreased microbial diversity, an expansion of potentially...
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Posted by admin on Mar 31, 2024 in |
Curcumin, a substance produced from the root of the plant Curcuma longa, has been used for thousands of years in Ayurveda and traditional Chinese medicine to treat a variety of inflammatory disorders. Curcumin, the turmeric key ingredient responsible for this function, was discovered over two centuries ago. Curcumin exerts its effects via altering a number of crucial molecular targets, including transcription factors, enzymes, cell cycle proteins and cytokines according to modern science. Curcumin is currently used to treat a variety of disorders, including psoriasis, osteoporosis, Alzheimer’s disease, diabetes, Crohn’s disease, arthritis, and cancer. The history of curcumin in India as well as its traditional uses have been covered in this review. An overview of the possible health advantages of curcumin is also included in this paper. Further research on curcumin is required in order to examine additional areas and its real-world therapeutic uses for...
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Posted by admin on Mar 31, 2024 in |
Bach Flower Remedies were identified by Dr. Edward Bach who was a physician and homoeopath. His discovery and life history for these flower therapy to atone and cure emotions is stated. It affirms that factors like depression, anxiety, stress, anger etc. affects emotions and triggers diseases. The 38 flower remedies emphasize on Bach’s Philosophy of seven principle of causes and its healing stages. Each remedy is allocated with morphological and taxonomical characteristics along with medicinal properties that link up to its psychological emotional state. The usage and diagnostic features are incorporated. Bach flower remedies have substantial scope as this simple system of naturally curing and managing emotions would be the medicament of the future. These remedies work as relaxant, anti-depressant and many other therapeutic effects. It is an alternative system of medicine that has efficacious outcomes where rescue remedy has fruitful...
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Posted by admin on Mar 31, 2024 in |
Indian spices and medicinal herbs are well known throughout the world. Both have many different physiological and pharmacological characteristics. The current biomedical research is mostly concentrated on finding chemicals extracted from natural sources that are pharmacologically efficient and have little to no side effects for application in food production and preventative medicine. Pepper (Piper nigrum) is a common spice found in both Eastern and Western cuisine. It helps in digestion and weight loss by encouraging the breakdown of fat cells and has a remarkable antioxidant and antibacterial impact. Numerous independent researchers have conducted experiments that show pepper and its main ingredient, piperine, to have a variety of physiological effects. In-vitro studies have shown that piperine can prevent oxidative damage by suppressing or inhibiting harmful free radicals and oxygen compounds that are reactive. Apart from anti-oxidant property, analgesic, anti-inflammatory, anti-diarrheal, antispasmodic, antidepressant, immunomodulatory, anticonvulsant, anti-thyroid, antibacterial, antifungal, hepato-protective, insecticidal, and larvicidal activities are just a few of the potential pharmacological effects of Piper nigrum L and its active component, “Piperine,”....
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