Posted by admin on Jul 31, 2024 in |
The estimation of pharmaceutical and biological materials typically uses the key qualitative and quantitative technique known as high performance liquid chromatography (HPLC). It is the most adaptable, secure, trustworthy, and quick chromatographic approach for drug component quality control. Uterine fibroids are non-malignant developments that create in the uterus. They are otherwise called leiomyomas or myomas. Fibroids can be asymptomatic, however when they really do cause side effects, they can incorporate weighty feminine dying, longer or more continuous periods, pelvic strain or agony, successive pee or inconvenience peeing, developing stomach region, blockage, torment in the stomach region or lower back. This survey conveys a detail portrayal of logical ways were printed for the assessment of uterine fibroids drugs and its mix medication in prescribed drugs and natural frameworks. This evaluation incorporates scientific ways like high performance liquid chromatography (HPLC) study for the assessment of uterine fibroids drugs and with a blend combination. The purpose of this article is to evaluate the use of HPLC for chromatographic analysis of medications used...
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Posted by admin on Jul 31, 2024 in |
Attempts are made in understanding drug action and its molecular interaction with multiple target in living cell using computational power as a tool leading to the emergence of Network Pharmacology (NP) and Telemedicine (TM). Network Pharmacology (NP) has been appearing as an important tool in underlining the complex relationship between the pharmacokinetic and pharmacodynamics of drug, aids in the discovery of new drug targets and repurpose existing drug molecules. TM is utilization of communication as a tool to disseminate all types of Pathological and Pharmacological aid to the costumer. This new advancement has made it possible to cut down geographical barriers, need for travel, managing and improving disease treatment in remote and urban areas through teleconsultancy, teleradiology, telepathology and teledermatology. Network Pharmacology and Telemedicine not only opens up new therapeutic options but also aims in improving safety, efficacy of drugs along with effective diagnosis and treatment of diseases by creating awareness thus likely to become the core methodology of healthcare delivering in the future. This article highlights the applications...
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Posted by admin on Jul 31, 2024 in |
Chemotherapy is a familiar treatment technique that uses chemical drugs to kill cancer cells. This technique affects normal healthy tissues because it is unspecific and has toxic side effects. Now a days, nano technology application in chemotherapy have helped to solve uncontrolled problems of drug delivery and other side effects. Nanoparticles (NPs) can provide outstanding advantages over conventional drug delivery by having excellent properties such as controlled mode of action, different methods administration, and the ability to transport organic and inorganic molecules. Special ligands attached to polymeric NPs target the tumour site because of their chemical affinity to the malignant tissues. This article reviews the characterization, fabrication and application of NPs used in cancer chemotherapy. Moreover, different forms of polymeric chemotherapy was explored and analysed to better understand the effects of nano particles on cancer...
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Posted by admin on Jul 31, 2024 in |
Chemotherapy-induced neutropenia (CIN) is a common and sometimes fatal side effect of treatment for acute lymphoblastic leukemia (ALL), the most common malignancy in individuals over 40. Antibiotics are used in addition to supportive care as a current treatment. Granulocyte-colony stimulating factor (G-CSF) has been tested in clinical studies as a supplementary treatment to reduce febrile neutropenia in children with ALL. Regarding cancer therapy, the grade and timing of CIN may have predictive and prognostic effects. The following factors are linked to CIN: advanced age, low nutritional and functional status, a history of major comorbidities, the disease’s stage, particular chemotherapy regimens, and combination therapies. The management of CIN in ALL is fraught with difficulties, such as the lack of a consensus nomogram for the risk assessment of febrile neutropenia and uncertain genetic risk factors. The advantages of treating FN with granulocyte colony-stimulating factor and the best course of antibiotics in an emergency must be clarified. The purpose of the review was to explore the function of G-CSF in the management of CIN in ALL...
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Posted by admin on Jul 31, 2024 in |
Clitoria ternatea (Blue tea) is a traditional medicinal plant belonging to family Fabaceae having generous amount of anthocyanins which possess majorly antioxidant properties. It contains wide range of phytoconstituents such as triterpenoids, flavanol glycosides, tannins, alkaloids, amino acids, proteins, ternatins (poly acylated anthocyanins) and carbohydrates etc. According to the data obtained from different in-vitro studies, this plant possess antioxidant, antimicrobial, antidiabetic, hepatoprotective, nootropic, central cholinergic, antidepressant, antianxiety, anticonvulsant, anti-inflammatory, analgesic, antipyretic, wound healing, anticancer and many other pharmacological properties. In this report various preclinical studies data revealed about the efficacy of Clitoria ternatea plant in the treatment of neurological, inflammatory and oxidative stress induced...
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