Posted by admin on May 31, 2024 in |
The most prevalent condition affecting the nails is onychomycosis. It is a typical nail fungal infection that causes millions of individuals globally. Yeasts, non-dermatophyte moulds, and dermatophytes can all be the cause. It’s not only results in physical discomfort but also has a major negative effect on the affected person’s quality of life. This infection affects the nails of the toes and fingers, causing discoloration, thickness, and brittleness of the nails. While the condition is not life threating, but it can be uncomfortable and unsightly, leading many patients to seek treatment. Previously these treatments ranged from oral medication to topical ointments and laser therapy, each with its benefits and drawbacks Fortunately, recent improvements in onychomycosis diagnosis and treatment have provided new hope for patients. It will deal with the recent treatment available and the novel treatment which can be developed. In this comprehensive review, we will explore the latest research and developments in the field, discussing novel treatment modalities, diagnostic techniques, and safety considerations. Additionally, new techniques include photodynamic...
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Posted by admin on May 31, 2024 in |
Varicose vein is a clinical class of Chronic Venous Disease also called the varicosites. Varicose veins are enlarged, swollen and twisting veins often appearing blue or dark purple. It is more common in women than men, superficial veins of the leg are under high pressure, hence this disorder is mostly seen in the leg. The pathophysiology includes genetic components, dysfunctional valves, and weak vascular walls. In order for conservative treatments like diet, dietary, and hydrotherapy to be effective, a high level of patient compliance is needed. Interventional therapies like surgery are also used to treat varicose veins. Although varicose veins are not considered an imminent threat to life, they may interfere with regular activities and develop gradually. As a result, the current review critically assesses the possible utility of herbal medication in the treatment of varicose...
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Posted by admin on May 31, 2024 in |
This review covers the research on the anticonvulsant properties of marketed drugs with their side effects and adverse drug reactions and the importance of medicinal plants and homeopathic medications in the treatment of epilepsy with the mechanism of actions with fewer side effects in comparison to allopathic medications that cause side effects which may be dangerous in some situations so to overcome these problem Ayurveda and homeopathy plays a major role. The new advancement in the management and cure of epilepsy with the help of several newly discovered compounds that are more advanced than the marketed drugs which are under clinical trials and have fewer side-effects than existing drugs and in coming years these compounds will be part of epileptic drugs. Development of the animal epilepsy model with the help of AI techniques to reduce the failure of the model, AI is a useful tool in drug discovery and can evaluate vast data easily and is a time-consuming...
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Posted by admin on Apr 30, 2024 in |
This review explores the multifaceted roles of Src kinases, a subfamily of non-receptor tyrosine kinases, shedding light on their involvement in diverse diseases. Src-family protein tyrosine kinases (SFKs) exhibit widespread expression across various cell types, influencing their behavior and functionality. Src’s presence in distinct subcellular locations, such as plasma membranes, perinuclear membranes, and endosomal membranes, underscores its versatility and potential impact on cellular processes. Research indicates a significant association between SFKs and various disorders, emphasizing their relevance as potential therapeutic targets. The intricate interplay of SFKs in cellular membranes suggests a nuanced role in disease pathogenesis. The comprehensive examination of Src kinase’s involvement in different cellular contexts contributes to a better understanding of its potential implications in disease development. In conclusion, this study underscores the pivotal role of Src kinase and positions it as a promising therapeutic target for addressing a spectrum of illnesses. By elucidating the intricate mechanisms through which SFKs operate in cellular membranes, this review advocates for further exploration of Src kinases as crucial players in...
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Posted by admin on Apr 30, 2024 in |
The need to deliver pharmaceuticals to patients quickly and with minimal side effects has driven pharmaceutical companies to invest in the development of novel drug delivery systems. Solid dose forms, such as pills, are difficult for pediatric and geriatric patients to swallow. The best treatment for this issue is a mouth dissolving pill that dissolves or disintegrates quickly in the oral cavity. Additionally, they produce a pleasant tongue sensation. ODT has benefits like enhanced Bioavailability, rapid action, and patient compliance. As a result, mouth-dissolved tablets are a desirable substitute for liquid and traditional tablet dose forms. In recent past, several manufacturing technologies such as sublimation technique, spray drying technique etc. are employed to overcome the limitations of conventional tablet dosage forms. The mouth dissolving tablets must undergo a variety of evaluations after they are created in order to ensure their long-term stability and improved therapeutic...
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