Posted by admin on Jul 31, 2023 in |
Chronic joint inflammation is a hallmark of the systemic inflammatory illness known as rheumatoid arthritis (RA), which eventually causes severe disability and early death. RA may impact any joint in the body. However, it mostly impacts the wrist and knee joints’ proximal interphalangeal, metacarpophalangeal and metatarsophalangeal joints. Around 1% of people worldwide are affected by it and women are 2-3 times more likely to be affected than males. Preclinical RA, genetic influences and environmental influences all have a role in the etiology of the illness. Since there is no recognized therapy for RA, achieving the lowest disease activity and, if possible, recovery remains the key goals of care. This review summarizes the research on the many RA therapy options, their mechanisms of action, side effects and novel drug delivery systems currently being used for non-steroidal anti-inflammatory drugs (NSAIDs). These delivery methods are discovered to be non-toxic, physiologically selective, compatible with cells and tissues and safe even at larger doses. The current study compares and contrasts numerous unique drug delivery...
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Posted by admin on Jul 31, 2023 in |
Objective: Gingival recession is one of the most common mucogingival defects for which patients seek periodontal therapy. Treatment options for gingival recession include surgical procedures with pedicle flaps, free soft tissue grafts, gingival veneering, restorations, etc. When multiple gingival recessions involving adjacent teeth are present, the first choice is to address all recession defects at one surgical time. This systematic review and meta-analysis aimed to compare the effectiveness of Alloderm over Connective Tissue graft (CTG) in managing multiple gingival recessions. Methods: A literature search with appropriate keywords was done with electronic databases viz. MEDLINE Ovid (from 1946 onwards); SCOPUS and EBSCO. (Multiple gingival recession) or multiple root coverage) and coronally advanced flap; (multiple gingival recession) or multiple root exposure) and connective tissue graft is the search term used. Results: Randomized controlled trials comparing Alloderm with CTG were included. The risk of bias of included studies was assessed, and metanalysis was done using Rev Man (VERSION 5.4). Of the 367 articles, only three went for meta-analysis. Conclusion: A statistically significant...
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Posted by admin on Jul 31, 2023 in |
Systems made of nanogel have been researched from a theoretical and practical standpoint. They are frequently utilized for coatings, cosmetics goods, targeted delivery systems, controlled delivery systems, and controlled delivery systems. Using the approach of making nanogels from polymer precursors, the gels are produced. The manufactured nanogels are acceptable to consumers since they are stable, delicious, and acceptable. Systems made of nanogel have been researched from both a theoretical and practical standpoint. They are frequently utilized for coatings, cosmetics goods, targeted and controlled delivery systems. This entrapment is made possible by the employment of nanogels. Future advancements in nanogels look promising and will increase medication delivery options. Every new investigation involves the development of cutting-edge polymer and mechanistic techniques with a potential function in treatments and innovation in nanogel manufacture. The advancement of biopharmaceutical characteristics of medicine expands the usage of these materials in several industries or other distribution methods. One of the best drug delivery technologies for ensuring a regulated or sustained medicine release is undoubtedly nanogels. However,...
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Posted by admin on Jul 31, 2023 in |
Implant insertion in a “fresh extraction socket” is reliable and effective. Often little discrepancy is there between the size of the implant and the wall of the socket, which needs to be filled before placing the implant. Hence, there is a need for graft material to fill this space. The main objective of this article is to review the role of “demineralized freeze-dried bone allograft” (DFDBA) in bone formation around immediate implants and how it affects the hard and soft tissues. Also, this review assessed the role of DFDBA on osseointegration associated with immediate...
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Posted by admin on Jul 31, 2023 in |
Tripura is a small hilly state in the northeastern region of India. The state has abundant precious plants with medicinal values, naturally increasing principally in hilly areas. The agro-climatic environment favors miscellaneous medicinal plants and is a hot spot for native medicinal plants. Many of the tribal peoples of the state are living in the deep forest area with adverse communication. From ancient times they have been using plant and their products to treat different body problems as they are familiar with the medicinal properties of locally available medicinal plants. Different parts of those medicinal plants are rich in different compounds and bioactive molecules like flavonoid, alkaloid, sterol, etc.. They use them in aqueous extract, raw, dried, or by preparing in different ways in patients suffering from different complications. The plant products protect against complications like indigestion, constipation, insomnia, chest pain, etc. Laportea interrupta is a plant that belongs to the Urticaceae family and is used by the tribals of Tripura as a therapeutic agent against several diseased conditions....
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