Posted by admin on Oct 31, 2023 in |
Since ancient times, natural products, especially plants have been utilized to treat variety of disorders, and an astounding number of contemporary medications have been created from them. All across the world, liver problems are prevalent. These conditions are only mildly handled traditionally; however, allopathic treatment always makes the situation worse when used to address more severe conditions. The current review offers summaries of plants (44 species from various families) with hepatoprotective qualities that may be discovered in literature sources from various databases and are properly categorized based on the parts utilized. Through the use of experimental animal models, all the plants were examined scientifically for their ability to protect the liver by testing certain parameters, such as liver indicators (AST, ALT, ALP, total protein content, albumin, and bilirubin), as well as through histological analysis, the hepatoprotective action was scientifically demonstrated. From the review, phytoconstituents such flavonoids, glycosides, terpenoids, and alkaloids are primarily responsible for medicinal plants’ hepatoprotective properties. It will be useful for the researchers to discover a field...
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Posted by admin on Oct 31, 2023 in |
Diabetes is currently not well managed in the allopathic medical system. The dysfunction and damage to several organs, including as the blood vessels, heart, nerve fibres eyes, kidneys, and, neurons are chronic repercussions of long-term blood glucose elevations. There are many different therapy options available, but they frequently have negative side effects and cannot provide complete relief. The key to addressing these kinds of problems is to identify novel therapeutic targets and use them in conjunction with the present diabetes treatment approaches. Herbal plants are now being used by researchers to combat the negative impacts of currently available medications. When managing diabetes using conventional treatment. Herbal plants are now being used by researchers to combat the bad impacts of currently available medications. Therefore, it is essential to develop more modern, plant-based medicinal approaches that can be safer and more accessible. This study looked at the anti-diabetic effects of different Mooringa oleifera species parts, including the fruits, seeds, leaves, pods flowers, and stems. The resulting extract was administered to diabetic-induced...
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Posted by admin on Oct 31, 2023 in |
Clinical trials (CTs) are carried out to investigate novel, patient-acceptable, and more effective interventional procedures. Specific regulatory criteria for conducting CTs are recommended by the country’s drug regulatory authority, and these guidelines are followed when conducting CTs. The USFDA oversees regulating CTs in the USA in accordance with the Federal Food, Drug, and Cosmetic Act’s 21 Code of Federal Regulations, Part 312 (CFR). According to the GCP Directive 2005/28/EC of the 8 April 2005 and the CT Directive 2001/20/EC of the European Parliament and of the Council of the 4 April 2001, they are under the control of the European Commission and EMA in the EU. Both the ICMR and the CDSCO (Schedule Y, D&C Act) have control over the Ethical Guidelines for Biomedical Research on Human Subjects. The European Commission’s objective of promoting an environment that is suitable to CTs within the EU is to be realised with the help of the Clinical Trials Regulation (CTR) (No. 536/2014). All interventional CTs involving medicines for human use that are...
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Posted by admin on Oct 31, 2023 in |
Cefpodoxime proxetil is an oral antibiotic belonging to 3rd generation Cephalosporin category. It has shown its antibiotic activity against both Gram positive and Gram-negative bacteria and has high stability in the presence of β-lactamase except Enterococci species. The drug has found its effectiveness in pediatric patients in treating respiratory tract infections. At the present time the most familiar form in which cefpodoxime proxitel is delivered is either oral tablet form or for pediatrics oral dry syrup form. The oral dry syrup form has to be administered twice or thrice a day in order to meet the required dosage regimen. Developing the sustained release formulation for cefpodoxime proxetil probably niosomal suspension can be effective in reducing the dosing frequency along with sustained release and targeted drug delivery. Niosomal suspensions are suspended form of niosomes in an aqueous phase to form liquid dosage form it is called niosomal suspension. It is a potential drug carrier for delivery of drugs orally in liquid form. The niosomal suspensions allow the targeted drug delivery...
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Posted by admin on Oct 31, 2023 in |
A spectroscopic method called Raman spectroscopy is frequently employed to discover the vibrational modes of molecules. Raman spectroscopy is frequently used in chemistry to give compounds a unique structural fingerprint. Using mass spectroscopy, one or more molecules present in a sample can have their mass to charge ratio (m/z) measured. It is frequently possible to estimate the precise molecular weight of the sample’s constituent parts using these measures. Raman spectroscopy and mass spectroscopy are complimentary analytical methods that are used to offer details on the chemical make-up and functional groups of the target analytes. Each device offers particular chemical data. When the raman spectroscopy is hyphenated with mass spectroscopy the interface used is a small piece of tissue paper. Biological Sample Analysis, New medication chemical analysis, to distinguish between positional isomers. The hyphenated approach makes it simple to get analytical findings such as molecular weights, chemical structures, and functional...
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