Posted by admin on Jul 31, 2023 in |
Nowadays, some medicinal plants have been reported to be useful in diabetes worldwide and have been used analytically as antidiabetic medicaments. Bundelkhand is a historic zone of central India. This region is known as the land of fighters, sacrifice, and love. It’s spread in the range of Uttar Pradesh and Madhya Pradesh state. It includes seven sections of Uttar Pradesh and six sections of Madhya Pradesh. Despite the presence of known antidiabetic drugs in the pharmaceutical request, diabetes, and related complications continued to be major medical problems. Antihyperglycemic effects of these plants are attributed to their capability to restore the function of pancreatic tissues by causing an increase in insulin production or inhibiting the intestinal immersion of glucose to facilitate metabolites in insulin-dependent processes. Diabetes mellitus (DM), also known as insulin-dependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus (NIDDM), is a common and serious metabolic condition that affects people each over the world. Traditional herbal plants have been employed to treat diabetes mellitus all throughout the world. Several herbs...
Read More
Posted by admin on Jun 30, 2023 in |
Even though the malady of dementia has existed for thousands of years, the correlated neurodegenerative alterations taking place in certain regions of the human brain were detected in recent times. Today, we are aware that dementia is a primary manifestation of Alzheimer’s disease (AD). In 1907, Alöis Alzheimer described the symptoms of a 51-year-old woman, Auguste Deter, who was under his observation at the state Asylum in Frankfurt (Germany). Alois Alzheimer noticed the existence of unusual accumulations in the brain (described as amyloid plaques today) and a massive loss of neurons while examining the brain of his first patient that suffered from memory failure, bizarre behavior and abnormal personality before death. With the enhanced lifespan, direct and indirect health expenditures of patients suffering from AD have increased exponentially. There is neither an appropriate experimental model for testing the memory of animals akin to human memory nor any cure for AD. It is important to investigate the past events resulting in AD to comprehend the present scenario and gain insight...
Read More
Posted by admin on Jun 30, 2023 in |
Rheumatoid Arthritis (RA) is an autoimmune inflammatory illness characterized by persistent synovial inflammation. It’s the most common form of arthritis that causes inflammatory changes in the tissue of joints, destroys cartilage and bones, and affects the quality of life. This diverse disease has a wide range of disease progression and treatment responses. Because the precise origin of rheumatoid arthritis is still unknown, no medicine can ensure a full recovery. Biomarkers guide the clinical and pharmacological management of rheumatoid arthritis at all phases. This is because they can help in the monitoring of disease activity and progression, the prediction of illness beginning in at-risk patients, and the provision of predictive data. American College of Rheumatology (ACR) emphasized on initial investigation of clinical findings based on the physical data for the diagnosis of RA. Although Rheumatoid factor and anti-citrullinated protein antibodies are the two biomarkers that can be used to determine who is at risk for the condition and who has pre-clinical rheumatoid arthritis before symptoms develop, there are involvements of...
Read More
Posted by admin on Jun 30, 2023 in |
The development of mucoadhesive buccal formulations has recently gained a great deal of attention. Despite several proposed solutions, drug permeability and regulated drug release via this mode of delivery remain concerns for successful therapy. Clinical uses for recent advances in nanotechnology have been examined. In addition to ensuring effective distribution, the use of nanoparticles in dosage forms for buccal administration also helps to minimize any negative effects on biological systems. To load and distribute drug-containing nanoparticles to the buccal mucosa for topical and systemic applications, several strategies have been proposed. In order to improve medication delivery or targeting, this study outlines contemporary cutting-edge approaches for using nanoparticles in dosage forms. Of give a general overview of current approaches to implementing controlled drug delivery, these technologies are categorized and discussed. All of these noteworthy results will promote novel nanoparticle-delivered dose formulations for buccal distribution in clinical settings. Overall, the buccal mucosa provides a lot of advantages for controlled pharmaceutical delivery over an extended period of...
Read More
Posted by admin on Jun 30, 2023 in |
The genus Ailanthus, which includes both evergreen and deciduous species, is native to both Asia and northern Australia. Traditional medicine relies heavily on this plant, and various components of the plant are utilized to treat a wide range of illnesses. Herbal and ayurvedic drugs have gained worldwide attention over the past decade for their potential health and financial benefits. There are now major worries about the quality, safety, and efficacy of herbs due to their regular and extensive use around the world. As a result, credible scientific data or evaluation is required before health claims made about herbs may be considered valid. The foundation for this tree’s status as a plant of heaven includes the traditional assertions, phytochemical studies, pharmacological examination and some ayurvedic formulations. Therapeutic effects are found throughout the plant. The bark is employed in treating dysentery, earaches, skin diseases, rectum problems, fever related to tridosha and alleviating thirst. Furthermore, it is prescribed for patients suffering from bronchitis, asthma, bronchitis, dyspepsia, gout and rheumatism. In Ayurveda, it...
Read More
