Posted by admin on May 31, 2023 in |
Endophytes constitute a remarkably multifarious group of microorganisms ubiquitous in plants and maintain an imperceptible association with their hosts for at least a part of their life cycle. Their enormous biological diversity, coupled with their capability to biosynthesize bioactive secondary metabolites, has provided the impetus for a number of investigations on endophytes. There is a need to search new ecological niches for the potential of natural bioactive agents for different pharmaceutical, agriculture, and industrial application; these should be renewable, eco-friendly, and easily obtainable natural products discovery in the search for new drugs and is the most potent source for the discovery of novel bioactive compounds. Therefore, a large number of bioactive compounds are isolated from plants, bacteria, fungi, and many other organisms. Endophytic fungi, the most promising of these, have been a source of various such bioactive compounds. Many of these compounds are being used for the treatment of a number of diseases. This review emphasis on the biology of fungal endophytes, their discovery, isolation, identification by morphological and...
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Posted by admin on May 31, 2023 in |
Neurons are the nervous system’s basic components that involve the spinal cord and brain. Neurons do not usually replicate or substitute them because the body cannot replace them as they get impaired or die. Neurological conditions are untreatable and disabling diseases that result in irreversible deterioration/death of the human brain’s nerve cells or neurons. Treating these conditions with extended synthetic drug administration can lead to serious side effects. So, herbal therapy is preferable over traditional therapies. Using herbal remedies can provide significant potential benefits in preventing and treating Neurological disorders. Herbal medicines have been gaining much attention for their therapeutic value over many years. Herbal plants have been used to treat and manage various ailments from ancient times due to their economic availability and lesser side effects than conventional anti-parkinsonian drugs. The current review incorporates research on medicinal plants, which has demonstrated the ability to transcend the development of neurological disorders and highlights the significance of traditional plant species in the role and mechanisms involved in neuroprotection. Ayurveda is regarded...
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Posted by admin on May 31, 2023 in |
Millets are one of the oldest foods known to humans and possibly the first cereal grain to be used for domestic purposes. The Indian flatbread roti is made from ground millet seeds. In malice of all these extraordinary rates and capacities of millet husbandry systems, the area under millet products has been shrinking over the last five decades and swiftly after the green revolution period. The bitsy “grain” is gluten-free and packed with vitamins and minerals. Millet grain is largely nutritive with good quality protein, rich in minerals, salutary fiber, phytochemicals, and vitamins. The nutritional composition of the millet is compared with that of rice and wheat. Value-added products from millet have the eventuality to add value to the business and grow as consumers believe that millets and millet-predicated foods contribute directly to their...
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Posted by admin on May 31, 2023 in |
Using plant extracts to synthesize metal nanoparticles is one of the easiest, most convenient, cost-effective, and ecologically acceptable ways of avoiding hazardous chemicals. As a result, many environmentally acceptable methods for the fast production of silver nanoparticles utilizing aqueous extracts of plant components such as leaves, bark, and roots have been described in recent years. This study highlights and expands on recent discoveries in the green production of silver nanoparticles (AgNPs) utilizing various plant extracts and their prospective uses as antimicrobial agents. A systematic in-depth discussion on the possible influence of phytochemicals and their concentrations in plant extracts, extraction solvent, and extraction temperature, as well as reaction temperature, pH, reaction time, and precursor concentration. Extensive details of the probable mechanism of AgNPs’ interaction with microbe cell walls, which leads to cell death and strong antibacterial activity, have also been developed. Furthermore, even though chemical techniques for shape-controlled synthesis are well-known, regulating the shape of biosynthesized AgNPs has numerous beneficial impacts on its...
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Posted by admin on May 31, 2023 in |
Coronavirus disease 2019 (COVID-19) pandemic has emerged as a major healthcare problem and has posed a great challenge to our existing healthcare facilities. Treatment of COVID-19 has been primarily based on repurposed drugs, drugs approved under emergency authorization or other options which are not thoroughly evaluated in patients with COVID-19, hence, lacking an adequate data on safety and efficacy. Public awareness and education regarding the potential benefits and safety concerns of the available therapeutic/prophylactic options are crucial to avoid ethical and medicolegal issues. Fundraising and global partnership are required to raise the research on potential older drugs likely to be repurposed, along with novel treatment options for COVID-19. A global effort is required to ensure the availability, distribution, and safer administration of COVID-19 vaccines. A rational and ethical approach is required to manage the patients with COVID-19. Equitable access to COVID-19 vaccines should be a priority to end this pandemic. In this review, we have focused on concerns regarding ethics and rational medicine use in view of the available...
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