Posted by admin on Jan 31, 2023 in |
Herbs have been a surviving unit since we were born on this planet. Currently, they are the most probed topic in the food industry or pharmacotherapy due to their multidimensional approach where one herb targets various diseases and proffers a wide range of health benefits. Moreover, some herbal supplements are merchandised globally, and people are devouring these products blithely to extract additional benefits. But taking any herbal formulation under unsupervised conditions may be subject to herbal toxicity. Hence, providing safe herbal supplements is a daunting challenge for various reasons: availability of unstandardized, contaminated, adulterated, loosely available, and unlabeled products, scanty regulations, herb-herb, and herb-drug interaction, and many others. The present article is enriched with past and most recent literature on processing crude herbs, the necessity of standardization of herbal products, the health benefits of standardized herbal medicines, and the toxicity of herbal formulations. The literature has also discussed a case study linked to herbal products, the importance of the pharmacovigilance system, and the challenges associated with the safety monitoring...
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Posted by admin on Jan 31, 2023 in |
Nanostructured Lipid Carriers (NLCs) is a novel type of drug-delivery system. They are binary system which is stable in a different environment. Nanostructured Lipid Carrier (NLC) comprises a blend of solid and liquid lipids as a core matrix. NLCs have aggravated the incessant impulsion for developing safe and valuable drug delivery systems due to their exceptional physicochemical and biocompatible characteristics. Additional utilization NLCs is crucial because of overcoming barriers enclosed by the technological procedure of lipid-based nanocarriers’ formulation and raised data on the core mechanisms of their transport via numerous routes of administration. NLC it can be easily used as a carrier for drugs via different routes of administration such as oral, parenteral, ocular, and nasal. Nanostructured lipid carriers (NLCs) have been reported to be an alternative system and are considered superior to many other traditional lipid-based nanocarriers such as emulsions, nanoemulsion, liposome, microparticle, and solid lipid nanoparticle (SLNs). It imparts many advantages over SLN’s such as increased solubility and stability, improved permeability and bioavailability, enhanced drug loading capacity,...
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Posted by admin on Jan 31, 2023 in |
Compounds with heterocyclic moiety are important for life and are abundant in nature. Heterocyclic compounds have a crucial part in the metabolism of all biological cells. Humanity relies heavily on nitrogen-based heterocyclic compounds. Benzimidazole, in particular, is a vital component of the entire nitrogen-based heterocyclic chemical family, not just physiologically but also industrially. Because once benzene, as well as imidazole, get merged around each other, a heterocyclic benzimidazole compound forms. Benzimidazole incorporates two nitrogens like a heteroatom. Benzimidazole analogues are often more powerful, medicinally significant chemicals with a wide range of biological activities. Benzimidazole analogues have been proven to be beneficial in several fields. The medicinal characteristics of benzimidazole analogue are diverse, including anticancer, antidiabetic, antihypertensive, and antimicrobial properties. Because of the medications’ uses in the treatment of microbe-related infections and other biological activities, stronger and more significant pharmaceuticals are being developed. These compounds have been found to be efficient against various bacteria in pharmacological tests. The antimicrobial property of several benzimidazole compounds is summarised in this...
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Posted by admin on Jan 31, 2023 in |
Neuropathic pain is a chronic illness that originates when abnormal functioning in the nervous system is observed or if the nervous system, including peripheral nerves, spinal cords, and brain, is damaged or not working properly, and originating pain. Therefore, it can be said that neuropathic pain is a chronic illness that directly impacts a large number of patients, society, and healthcare systems all over the world. The prevalence of neuropathic pain is believed to be 7-8% in the general population, and it is supposed to rise in the future. The impact of neuropathic pain on older persons is significant. The medical practitioner faces a problem in reducing neuropathic pain symptoms and improving the patient’s quality of life. Older people are easily and badly affected by neuropathic pain and are more susceptible to specific adverse effects. Neuropathic pain is different from nociceptive pain, and there is a requirement for a different treatment strategy for neuropathic pain management. The present review article is based on a detailed literature survey on etiology,...
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Posted by admin on Jan 31, 2023 in |
Introduction: Gold preparations are highly prized and often utilized for their tonic and revitalizing effects in Indian systems of medicine. Gold has both preventive and curative medicinal properties. The Kashyap Samhita, under the name Swarnaprashana, describes the usage of gold internally in children via the oral route. After birth, it is indicated in Lehan karma (supplementary feeding to improve nutrition, immunity and intelligence) and Jatkarma (newborn care). Now a day Swarnaprashana in children is getting huge publicity, and many trials are being conducted to evidence its use in children. Material and Methods: This review is in a narrative format and consists of all publications relevant to Swarnaprashana or Swarnabinduprashana, Suvarnabindu prashan, Suvarnavachayog, or Swarnavachayog that the authors identified through a systematic search of major computerized medical databases; no statistical pooling of results or evaluation of the quality of the studies was performed due to the widely different methods employed by each study. Result and Discussion: The present review of the studies proves the role of Swarnaprashana in enhancing cognition...
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