Posted by admin on Jan 31, 2023 in |
Keratin is a structural protein from the intermediate filament network, i.e., responsible for maintaining the keratinocyte’s structural integrity. Pachyonychia congenita is not a lifetime disease. It is a rare dermatosis disease occurred in the sole’s feet and palm’s hand. In this review, we have discussed the keratinization that occurs in the stratum corneum that follows mutation in the keratin gene “rare disease” pachyonychia congenital an autosomal dominant disorder or hereditary syndrome by any one of a missense mutation in keratin genes such as KRT6A, KRT6B, KRT16 and KRT17. This disease shows hypertrophic dystrophy in toenails and fingernails, plantar keratoderma, oral leukokeratosis, cysts, and follicular hyperkeratosis in the hair follicles. This review aims to specify the beneficial surgical treatment for the pachyonychia congenita. There is limited treatment for this disease, only for the clinical manifestations. In the future perspective, pachyonychia congenita may be treated with C2H4O3 lotions/creams and Keratolytics creams available in the marketed...
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Posted by admin on Jan 31, 2023 in |
Acute gastroenteritis prevalent amongst children and newborns is considered a serious infection globally. The Acute diarrhea as a result of gastroenteritis as per logistics suggest that there were more than 1.5 million outpatient visits along with 200,000 hospitalizations and 300 fatalities per year in children in U.S. Diarrhea is the leading cause of deaths amongst children with 30% relapse rate. The viral gastroenteritis caused by the Rotavirus is one the significant strain contributing the gastroenteritis. The suggestive therapies include Oral rehydration therapy (ORT) respective to age modulating the diet and ORS solutions. The gastroenteritis condition cannot be neglected but can be considered as significant public health issue especially in the elder patients with fatality ratio compared to children. The diagnosis of gastroenteritis includes signs, symptoms and stool cultures. The comorbidities in the patients when treated with variety of drugs is resulting damage of stomach lining and worsening the conditions of gastroenteritis. The comorbidities include the cardiovascular diseases, kidney related diseases and other infections playing major role for the chronic...
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Posted by admin on Dec 31, 2022 in |
Nutraceutical is a word obtained from Nutrition and Pharmaceuticals. Nutrients are a feed constituent that helps to support the life of human beings or animals. Pharmaceutical components are non-toxic food constituents, including prevention and treatment of disease. They commonly inhabit the disorders associated with oxidative stress, for instance, cardiovascular disease, Diabetes, and Hypertension. Nutraceuticals possess substantial importance because of their expected safety and possible nutritional and therapeutic effects. Hypertension is the most frequent risk factor for cardiovascular disease involving coronary heart disease and stroke. There is a crucial role in utilizing single and integral nutraceutical supplements, vitamins, antioxidants, and minerals in the treatment of hypertension. These food supplements rein huge demand because they are less toxic and have long life treatment with dietary food. We have done a face-to-face survey on 33 medical stores. The survey results found that the most demanding nutraceutical is Mactotal, and the least demanding nutraceuticals are Beryl tone and Allvell-Z graph seed extract. The survey study also shows a list of Nutraceuticals that are...
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Posted by admin on Dec 31, 2022 in |
In the present study, phytochemical and pharmacological properties of species of F. benjamina have been discussed. The phytochemical and pharmacological properties correlate with various active constituents of the plant. Ficus belongs to the Moraceae family, found in Asia and Australia, and widely distributed in tropical and subtropical areas, including more than 800 species. The genus Ficus constitutes a major tree group with numerous chemical constituents of promising medicinal value. Morphological characteristics of the plant show that it is a fast-growing plant and moderate to high-temperature conditions are more favorable for the fast growth of the plant. A microscopical study has shown the existence of various cells. Different plant parts have been extracted using different solvents and many bioactive compounds, chiefly stigmasterol, quercetin, cinnamic acid, lactose, naringenin, caffeic acid extracted, and isolated from roots, fruits, leaves and barks. Ficus benjamina is used by distinct native population groups in many ways as its bark, leaves, roots, fruits, and stem shows various therapeutic uses. Additionally, the stem and bark latex also shows...
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Posted by admin on Dec 31, 2022 in |
Carbon nanomaterials belong to the carbonaceous family of less than 10 nm in size called Carbon dots (C-dots); the latest class of engineered nanoparticles has recently gained popularity for their unique characteristic features, such due to their low toxicity and miniature size, it can penetrate cells easily, thus becoming highly biocompatible. The advancement of science and its collaboration with multidisciplinary fields for developing C-dots, their characterization, and application into the faster, cheaper, and more reliable products in various scientific areas. C-dots synthesis uses biomass wastes because of their abundance, wider availability, low cost in terms of higher production rate, non-toxic and eco-friendly. Here biomass has been used as a carbon source from renewable raw materials, such as plant and animal derivatives, agricultural wastes, etc. This review aims to summarize the upgrading and recycling of biomass waste to produce C-dots, sources of biomass wastes, characterization of structure and composition, regulation of fluorescence, heteroatom doping, and its unique photoluminescence and chemiluminescence characteristics that make the C-dots most promising nanomaterial used for...
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