Posted by admin on Oct 31, 2022 in |
Diabetes mellitus is an associated symptom of untreated high blood sugar, and it’s linked to long-term organ damage, dysfunction, and failure in adults. The ongoing increased scale of Diabetes mellitus will severely impact the long-term health of the global population and the global economy unless appropriate prevention and management strategies are established. Plants were studied using streptozotocin-induced diabetes rodents’ in-vivo animal models. As per the World Health Organization, more than 90% of people in underdeveloped countries use natural medicine (plants and their products) for primary health care. Approximately 800 plants have been identified to have anti-diabetic properties. The following are the most commonly utilized plant extracts to help regulate blood glucose: Allium cepa (Onion), Allium sativum (Garlic), Aloe barbadensis (Aloe vera), Azadirachta indica (Neem), Beta vulgaris (Beetroot), Catharanthus roseus (Vinca rosea), Cinnamomum cassia (Cinnamon), Curcuma longa (Curcumin), Eugenia jambolana (Jamun), Hibiscus rosa-sinesis (Gurhal), Mangifera indica (Mango), Momordica charantia (Karela), Nigella sativa (Kalonji), Ocimum sanctum (Tulsi), Panax ginseng (Ginseng), Pterocarpus marsupium (Vijyasar), Psidium guajava (Guava), Tamarindus indica (Tamarind), Trigonella foenum-graecum...
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Posted by admin on Oct 31, 2022 in |
Psidium guajava Linn is an herbal remedy used in Ayurveda as a traditional system of medicine in ethnomedicine. It is a tropical evergreen plant that grows in tropical and subtropical climates. It has a wide variety of nutritional components. The whole plant and various parts of the plants possess different types of therapeutic activity, such as Tannin, phenols, triterpenes, flavonoids, essential oils, saponins, carotenoids, lectins and vitamins, dietary fiber, fatty acids, and other active components of guava plants demonstrate pharmacological activity. The fruits and leaves can be freely consumed for their good taste and various nutritional benefits and can be used in various treatments. The most active constituents, like tannins, flavonoids, terpenoids, etc., are mainly found in leaf parts. Guava has a high nutritional value, as it is high in dietary fiber, vitamins C and A, folic acid, dietary minerals, potassium, copper, and manganese. Guava leaves have phenolic compounds which are reported to possess antibacterial, antistress, antigenotoxic, anti-inflammatory, anti-hyperglycemia, anti-rotavirus, cytotoxic, hepatoprotective, etc. In this review, compile all the...
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Posted by admin on Oct 31, 2022 in |
The Petasis boron–Mannich process, also referred to as the Petasis reaction, combines boronic acid, an amine, and a carbonyl derivative in a multi component coupling process. Recent progress on petasis reaction is discussed in this review. The various merits of petasis reaction over the other multi-component coupling reactions are explain here. Noncanonical substrates are used to explore the expansion of a variety of petasis reactions, including two–component, three–component, and four–component reactions, processes, and products. In this review, Microwave–assisted reactions are also explored. The optimal conditions are involved in the microwave heating process. The conditions are successfully applied for petasis reaction. Different solvents are used in petasis boron-mannich reactions, such as glycerol and water. Both solvents are suitable for the reaction and give favorable yield. The reactivity along with numerous synthetic applications of the Petasis reaction are given in this review. The natural product synthesis are given by Petasis boron-Mannich reaction in which loline alkaloid and sialic acid synthesis are...
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Posted by admin on Oct 31, 2022 in |
Cancer refers to a group of diseases characterized by abnormal, unchecked cell growth that spreads to other body parts. Breast, liver, colorectal, kidney, stomach, lungs, and cervical cancer are the most common tumours, with skin cancer (excluding melanoma) being the least common (contributing up to 40 percent of the cases). Surgery, chemotherapy, and other traditional medical methods have several negative side effects, including extreme inflammation and discomfort. As a result, transdermal delivery of the anticancer drug transdermal patch may be beneficial for treating multiple breast cancers via the skin. Transdermal drug penetration using various methods, such as nanocarriers, tactile penetration enhancing tools, chemical penetration enhancers, and newer innovations, such as gels, dendrimers, needle-free injection jets and so on, results in increased patient compliance, scar elimination, and economic benefit. Topical antineoplastic drug delivery is a popular option for increasing site-specific delivery, mitigating side effects, and enhancing therapeutic effects. This study aims to discuss the transdermal delivery of anticancer agents via the skin, which can open up a new frontier in...
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Posted by admin on Sep 30, 2022 in |
The reason for this assessment became the blessing of the use of nanoparticles in lung disease. Nanotechnology has a critical characteristic in inhalation. The dosage shape of pulmonary drug shipping reaches to without delay into a scientific cycle to obtain the impact of the drug. The nanoparticles have a nanosize that achieves the preferred healthy without inflicting infection as compared to standard dosage forms. Various dosage kinds of the pulmonary drug shipping device meet the necessities of this assessment, like metered-dose inhalers, dry powder inhalers, and nebulizers. This drug has a significant impact on the target site. They are used for all kinds of diseases, including asthma, lung cancer, tuberculosis, and various lung diseases. You should easily get a nanometer particle length in the right place. Due to the physiological properties of the lung, the lung is suitable as a target organ for non-invasive short-range and systemic delivery of drug, primarily for non-bioavailable proteins and water-insoluble capsules for conventional drug delivery. Recently, inhaled nanoparticles have been shown to produce...
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