Posted by admin on Aug 1, 2010 in |
Yoga and exercise are an efficient way of declining patients of hypertension in present and in future. However it has been shown that Non-pharmacological intervention prevent the rising blood pressure and reduce it up to maximum extent, near to the normal. This experiment was designed to determine effectiveness of Yoga and exercises therapies to control blood pressure of hypertension patients. The objective was to employ these Non pharmacological therapies to know it’s effectiveness in treatment of hypertension along with pharmacological therapies in conventional way. We tested the short-term efficacy and feasibility to the treatment of hypertension in a small South Gujarat’s industry employees who are living under modern life-style. This was follow-up by physician for 12 months. Of 1031 a small South Gujarat’s industry employees screened, 221 individuals (aged 35 to 60 years) were selected with hypertension. Mental and physical stress-reduction approaches (Meditation and progressive muscle relaxation) were compared with a life-style modification education control program and with each other. The primary outcome measures were changes in clinical diastolic...
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Posted by admin on Aug 1, 2010 in |
A series of 3- (5- substituted phenyl- 1, 3, 4- Oxadiazol- 2- yl) pyridines was designed, synthesized and characterized for evaluation of potential antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Klebsiella species and antifungal activity against Candida albicans. Structure-activity relationship led to the conculsion that compound IVb, and IVe exhibited good antibacterial activity against Bacillus subtilis and Staphylococcus aureus and comparatively poor activity against Klbesiella species and Escherichia coli. Compound C exhibited antibacterial activity against Staphylococcus aureus and very poor activity against rest of organism. Compounds IVa, IVb and IVe showed poor antifungal activity against Candida albicans and compounds IVc and IVd showed no significant antifungal activity. The interesting antimicrobial profile of compound IVb and IVe led us to select this derivative for further development. Present research our expected compounds were given below....
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Posted by admin on May 1, 2010 in |
Tuberculosis is declared to be an infectious disease of global emergency by WHO. Approximately one-third of the world’s population is infected with the tuberculosis. The lengthy and laborious current treatment of 6-9 months is associated with problems like patient noncompliance, multiple drug resistance and persistence of mycobacterium and significant toxicity of drugs. The increasing emergence of drug resistance of mycobacterium highlights an urgent need to develop novel therapeutic targets and agents that are not only effective against drug resistant bacteria but can also herald the persistent form of bacteria and thereby shorten the length of TB treatment. However, an approach towards understanding the physiological characteristics of the mycobacterium and designing of such novel therapeutic agents that are effective against drug resistance & persistent bacteria can bring about a revolution in the TB chemotherapy in near...
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