Posted by admin on Dec 1, 2014 in |
The present chemical analysis deals with Asparagus racemosus root for phytochemical screening and GC-MS analysis. Phytochemical constituent of the root extract was carried out according to the standard method. GC-MS analysis was performed on the methanolic extract of A. racemosus to find out the chemical constituents. The phytochemical screening revealed the presence of flavonoids, alkaloids, steroids, terpenoids, glycosides, tannins, terpenoids, saponins. GC-MS results revealed the presence of 6 different phytochemical constituents like, 2-Propanone, 1,3-dihydroxy 1), 2-Fruancarboxy aldehyde, 5-(hydroxymethyl) 2), Hexadecanoic acid 3), n-Hexadecanoic acid 4), Ethanol,2(Octyloxy)- 5), 1,9-Nonanediol 6). The presence of various biological active compounds confirms the application of A. racemosus for various diseases by conventional practitioners. The obtained phytochemical constituent results demonstrate that the methanol root extract of Asparagus racemosus could be used corn foot, anticancer, diabetic healer. However, isolation of individual phytochemical constituents might be useful to formulate a novel...
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Posted by admin on Dec 1, 2014 in |
Andrograhis paniculata is a wonder drug using in traditional systems of medicine for multiple clinical applications. This research article deals with the phytochemical and antioxidant properties of A. paniculata leaves. Qualitative and quantitative phytochemical analyses were carried out by TLC and HPLC method. Physico-chemical analysis was done to standardize the plant drug material so as to ensure the use of genuine material. The result of phytochemical studies confirmed the presence of various secondary metabolites like alkaloids, glycosides, flavonoids, proteins, tannins, phenols, saponins, terpenoids, quinones and steroids. TLC studies of chloroform extracts showed 3 spots and methanol extracts showed 5 spots at different Rf values. HPLC analysis confirmed the presence of the major active constituent andrographolide. Effect of age on quantity of andrographolide content was studied and it was found to be higher in 120 day old plants. Antioxidant property was determined by reducing power method. Maximum antioxidant activity was observed in pure andrographolide followed by methanol and water extracts of leaf...
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Posted by admin on Dec 1, 2014 in |
Blood pressure (BP) is one of the major prognostic indicators in cardiovascular patients and in patients with chronic kidney disease (CKD). Accurate measurement of BP is important to classify an individual to confirm BP related risk and to continue treatment. The limitations of conventional technique can be surpassed by ambulatory blood pressure monitoring (ABPM). ABPM strengthens its superiority towards clinical BP measurement in point of its high reproducibility, high cost-effectiveness, assessment of white coat hypertension, provides multiple BP measurements. This review highlights ABPM technique and covers a brief introduction about hypertension, measurement of BP by 24-hr ABPM, clinical indications in various areas, ABPM device and its application thereby concluding that ABPM technique is superior both in terms of care and cost over conventional technique for diagnosis and treatment of...
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Posted by admin on Dec 1, 2014 in |
The antidiabetic potential of ethanolic extract of bijasar (Pterocarpus marsupium Roxb.) heartwood was evaluated in the streptozotocin-nicotinamide induced type 2 diabetic model. Graded doses of the ethanolic heartwood extract were administered to normal and experimental diabetic rats for 12 days. Significant (p < 0.05) reduction in fasting blood glucose levels were observed in the normal as well as in the treated diabetic animals. In addition, changes in body weight, serum lipid profiles, thiobarbituric acid reactive substance levels, glycosylated hemoglobin and liver glycogen levels assessed in the extract treated diabetic rats were compared with diabetic control and normal animals. Significant results were observed in the estimated parameters, thereby justifying the use of the bijasar heartwood by Indian herbal practitioners for treatment of diabetics in different part of the Indian...
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Posted by admin on Dec 1, 2014 in |
Ravenala madagascariensis Sonn. is one of the most popular medicinal plants in Madagascar, India and several African countries. It is used in the treatment of many diseases, and particularly in those of diabetes. The duration of treatment, often for life, and its relatively high cost for certain social categories, constrain more and more patients to use this plant. Its chemical constituents were still little studied and this problem could create significant damage in case of intoleranceor abuse during its use.The present study undertaken on the leaves of Ravenala madagascariensis, led to the isolation and structural elucidation of two new compounds (1 and 2), together with the known cycloartanol triterpene (3) which was isolated for the first time from this plant. Their structures were elucidated as (2E, 7R, 11R) phytyl-3, 7, 11, 15-tetramethylhexadec-2-enyl pentadecanoate (1) and (24S, 31S)-cycloartan-31, 32-diol (2). Structural determinations were made on the basis of analysis of 1D and 2D-NMR spectroscopic data. The complete 1H and 13C resonance assignments were also carried out by using 1H-1H COSY,...
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