Posted by admin on Nov 1, 2010 in |
Comparative Pharmacognostical studies of Anisomeles Linn. R. Br. species (Lamiaceae) in India are carried out. These species are Anisomeles indica L. Kuntze (Syn. A. Ovata R. Br.) and Anisomeles malabarica L. R. Br. Ex Sims, which are highly found in throughout south (Deccan plateau) and northeastern India. The study conducted with the aim of drawing the Pharmacognostical standards for differentiate the species. Macroscopical and microscopical characters, physio-chemical constants, quantitative microscopy parameters, extractive values, fluorescence analysis of extracts, its reaction after treatment with chemical reagents under visible light and UV light carried out. Preliminary phytochemical screening and TLC fingerprint on the various extracts from aerial part of Anisomeles species was also studied. According to the anatomical comparison between two species, the pith structure, sclerenchyma ring of the stems, the cuticle thickness of the leaves, and stomatal distribution on the leaves are the distinguishing features of the species. The determination of these characters will help future researchers in their Phytochemical as well as Pharmacological analysis of this...
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Posted by admin on Nov 1, 2010 in |
The present study was aimed at evaluating the antidiabetic activity of aqueous extract of fruits of Artocarpus heterophyllus (Moraceae) in alloxan induced type- II diabetes in rats. The diabetic rats were administered aqueous fruit extract (250 and 500 mg/kg, p.o., n = 6) or vehicle (gum acacia solution) or standard drug glibenclamide (0.25 mg/kg) for 15 days. Blood samples were collected by retro-orbital puncture and were analyzed for serum glucose on 0, 5, 10 and 15th day by using glucose oxidase-peroxidase reactive strips and a glucometer. In oral glucose tolerance test, glucose (2gm/kg, p.o.) was administered to nondiabetic control, glibenclamide (10 mg/kg, p.o.) and extract treated rats. The serum glucose levels were analyzed at 0, 30, 60 and 120 min after drug administration. The effect of the extract on body weight of the diabetic rats was also observed. The serum insulin level and lipid profile were estimated. The extract showed significant reduction (p<0.05) of fasting blood glucose level in alloxan induced type- II diabetic rats on 10th and 15th...
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Posted by admin on Nov 1, 2010 in |
The aim of this study was to evaluate antimicrobial activity of the leaves of the Bauhinia racemosa L. In the current study, the aqueous and methanol extract of leaves of B. racemosa L. was tested against standard bacterial and fungal cultures. In vitro antimicrobial test was performed by agar well diffusion method on Mueller hinton agar and Sabouraud dextrose agar for bacterial and fungal cultures respectively. Minimum inhibitory concentration test was performed by modified agar well diffusion method. Methanol extract showed significantly higher inhibitory effect compared to aqueous extract on tested organisms. The methanol extract showed a broad spectrum of antimicrobial activity as it inhibited Gram negative bacteria (Escherichia coli, Micrococcus luteus, and Pseudomonas aeruginosa), Gram positive bacteria (Bacillus subtilis) and fungi (Candida albicans and Aspergillus niger). Both extracts showed maximum relative percentage inhibition against A. niger. MIC values for methanol extract varied from 1.5-25 mg/ml. Phytochemical analysis of crude methanol and aqueous extract suggested the presence of protein, oil and fats, phenolic compounds, flavonoids, saponins tannins and carbohydrates...
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Posted by admin on Nov 1, 2010 in |
Herbal medicines make up an important module of the fashion toward alternative medicine. It is becoming ever more popular in today’s world as people seek out for natural remedies. These medicines have been used since the dawn of civilization to maintain health and to treat various diseases. To compete with the growing pharmaceutical market, there is an exigency to develop and scientifically validated more medicinally useful herbal products. This review provides an outline of herbal medicines which is aimed to depict out pharmacovigilance, including standardization of these herbal...
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Posted by admin on Nov 1, 2010 in |
In recent time, scientific investigations of medicinal plants using indigenous medical systems has attracted a lot of attention globally. Nature has bestowed our planet with an enormous wealth of medicinal plants have been known for millennia and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention and cure of diseases and ailments. Inflammation is complex biological response of vascular tissue due to different harmful stimuli and pain is discomfort signals result of actual or potential injury to the body may associate with inflammation. Inflammation with pain is associated with different diseases like rheumatism, encephalitis, pneumonia, oesophagitis, cancer, heart problems, fibrosis etc. Nonsteroidal anti-inflammatory drugs and opioid analgesic are normally used in the treatment of inflammation and pain but can cause a lot of adverse effect. Therefore herbal drugs can be potential source to replace them. Every year a lot of plants form traditional medicinal system has been screened for their potential anti-inflammatory and analgesic activity but only few of them only...
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