Posted by admin on Sep 1, 2010 in |
Keywords: Pterospermum acerifolium, Pharmacognosy, Sterculiaceae, Drug StandardizationPterospermum acerifolium plant is considered to be laxative, anthelmintic, stomachic and used in inflammation, blood disorders, ulcers and leprosy. The leaf was studied for pharmaconostic evaluations, including examination of morphological and microscopic characters, determination of leaf constants, ash values and extractive values. The morphological studies revealed that the leaf is dark green color with a glabrescent texture and characteristic odour. In the microscopic studies, the leaves showed the presence of long, lignified stellate and four armed trichomes, anomocytic and paracytic stomata, 2 layers of radially elongated palisade cells below upper epidermis, collenchyma, vascular bundles and spongy parenchyma. The total ash, acid insoluble ash and water-soluble ash values were observed to be 4%, 1.4% and 2.5% respectively. The leaves were successively extracted with Petroleum ether, chloroform, ethyl acetate, methanol and water in increasing order of polarity. Preliminary phytochemical investigation showed the presence of alkaloids, glycosides, tannins, triterpenoids, carbohydrates and flavonoids....
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Posted by admin on Sep 1, 2010 in |
In recent times, focus on plant research has increased all over the world and a large body of evidence has collected to show immense potential of medicinal plants used in various traditional systems. Solanum nigrum (commonly called Makoi) is also a medicinal plant. A dietary intake of Solanum nigrum supplies our body with nutrients that offer protection against numerous diseases. All parts of this plant are used in the traditional medicine as a remedy for treating various diseases like, cough, cold, asthma, skin diseases and liver problem. Now a day, Diabetes mellitus has become a real problem of public health in developing countries. This is a metabolic disorder characterized by disarrangements in carbohydrate, protein and fat metabolism caused by the complete or relative insufficiency of insulin secretion and /or action. This is due to defective or deficient insulin secretary response. This results into impaired glucose use, which is a characteristic feature of diabetes mellitus i.e. resultant hyperglycemia. Elevated blood glucose level causes dehydration of the tissue cells as glucose...
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Posted by admin on Sep 1, 2010 in |
Medicinal plants are important source of potentially useful structures for the development of novel chemotherapeutic agents. The present study was aimed to evaluate the antifungal effect of partially purified C. gigantea latex extract on some human pathogenic fungi. Ethanolic extract of the latex were tested in vitro against fungi strains. The inhibitory effect was assessed by disc diffusion method. The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were also determined by serial dilution method. The ethanolic extract was subjected to qualitative phytochemical screening for the presence of bioactive ingredients. The ethanolic extract shows the presence of many biologically active molecules such as flavonoids, alkaloids, triterpenoids, steroids, saponins, phenols and glycosides. The latex extract shows significant zone of inhibition in dose dependent manner. The MIC and MFC values of latex extract against fungal strains varies from 1 mg to 8 mg and the results are comparable with Amphotericin B. From this study, we conclude that the latex extract possesses potent fungicidal activity which may be due to the...
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Posted by admin on Sep 1, 2010 in |
Objective of the study was to assess the antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats. Methods: The antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats was assessed using Alloxan β- cytotoxin induced chemical diabetes in a wide variety of wister albino rats. Result: The polyherbal formulation contain the following plants leaves of Caesalpinia bonducella, Mucona puriens, Pongamia pinnata. The extracts were prepared by continous hot soxhlet extraction using petroleum ether and water. Conclusion: The study reveals that the polyherbal formulations have antidiabetic activity and the action may be due to the restoration or regeneration of β-cells of...
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Posted by admin on Sep 1, 2010 in |
The optimization of this study is biochemical effect of protein in Liver, Kidney, Uterus and Ovary of albino rats (Sprague-dawley strain) weighing about 200-250gm treated orally of ethanolic extract of plant Tridax procumbens at 300mg/kg body weight concentration for 3 and 5 days chronically. The result showed that both treated groups of rats are not showing very significant changes in protein content of Liver, Kidney, Uterus and Ovary of rats as compared to their control groups. Therefore, it is safe to use it against various...
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