Posted by admin on Jul 31, 2021 in |
The present paper deals with the pharmacognostical and phytochemical investigation of Fumaria parviflora Lam. whole plant. The qualitative and quantitative phytochemical analysis was carried out for the important bioactive constituents present in Fumaria parviflora Lam. (whole plant) in its Hydroalcoholic extract. The preliminary phytochemical analysis showed the presence of alkaloids, phenols, flavonoids, carbohydrates, protein, steroids, and sulphate. The total phenolic content (TPC) and the total flavonoid content (TFC) were also determined from the extrapolation of calibration curves which were prepared by using Tannic acid and Quercetin respectively as standard solutions. The results indicated the presence of phenols and flavonoids in considerable amounts. Thus, the study revealed the presence of various bioactive constituents in F. parviflora which could be exploited for their potential applications for medicinal...
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Posted by admin on Jul 31, 2021 in |
Cancer is a serious health concern in both developed and developing nations. Cancer causes due to unwanted growth of cells and irregular cell division. Medicinal plants have been used by village folk from ancient times. The plants contain various bioactive compounds that can be used for treating cancer. Some of the phyto compounds isolated from plants have shown promising results; these include curcumin, vinblastine, vincristine, camptothecin. The various phytochemicals like terpenoid, flavonoids, and coumarins were also found promising in treating cancer. A lot of plants based compounds are under trial resulted in good responses. Around 17 different plant families, members with their active constituents reported for targeting cancer pathways were summarized. In this review, various medicinal plants which are reported for anticancer drug discovery were listed and mentioned for their mechanisms of action, such as CDK inhibitor, roles of apoptosis, and angiogenesis in cancer pathways. These plants are very useful in various research studies or for research purposes; these plants seek considerable...
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Posted by admin on Jul 31, 2021 in |
Several studies undertaken in the recent past have demonstrated that endophytic fungi are capable of producing a number of important bioactive secondary metabolites, hitherto known only from plants, thereby raising the potential of using endophytes as alternative sources for these metabolites. Occasionally, the compounds produced by endophytic fungi are similar to those produced by the respective host plants. The plant chosen for the current study has significant medicinal and therapeutic value, and endophytic fungi were isolated from the leaves of this plant. The leaves have been specifically chosen for this study as there is significant evidence suggesting that the leaf extracts of these plants have higher medicinal value. The hypothesis of this current study is that endophytic fungi isolated from leaves of the medicinal plant and its extract would exhibit similar or greater medicinal properties as that of leaf extracts. This work intends to highlight the bioactive potential of endophytic fungus Curvularia lunata isolated from Ficus religiosa. Extracts obtained from the fungi understudy were tested in-vitro for their possible...
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Posted by admin on Jul 31, 2021 in |
The present study was carried out to investigate the phytochemicals, Total polyphenolic content and In-vitro antioxidant activity of ethanolic and aqueous extracts of Cordia obliqua fruits. Objective: To determine the primary and secondary metabolites present in different extracts, to aces the quantity of phenolic compounds by total phenolic content and to evaluate the % inhibition of free radicals by in vitro antioxidant activity of Cordia obliqua fruits Methods: The plant material was extracted with solvents with increasing order of polarity and phytochemicals were identified by different chemical tests. Preliminary phytochemical studies of fruit extracts of Cordia obliqua revealed the presence of phytoconstituents like glycosides, alkaloids, tannins, phenols, saponins, in the extracts. The different concentration of extracts and standard ascorbic was used to identify the scavenging effect by in-vitro antioxidant models. Results: Phytochemical analysis of extracts revealed the presence of glycosides, alkaloids, tannins, phenols, saponins. The phenolic content in different extracts was found to be 150.16, 174, and 231.39, respectively. The results of in-vitro antioxidant tests suggested that the ethanolic...
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Posted by admin on Jul 31, 2021 in |
Distinctive groups of fungi are involved in the symbiotic association with epiphytic orchid. We have isolated endophytic fungi from Cleisostoma tenuifolium epiphytic orchid found in the Western Ghats and used morphological criteria as well as molecular techniques to identify these fungi. Characterization of these fungi was done by analyzing the quantified genomic sequences, and then identification was done by comparing the ITS region sequence of obtained fungi with its closely related fungal species from the NCBI database. Molecular techniques were useful in identifying endophytes to its species level. The vast range of endophytes from a single type of orchid further highlights the importance of forest epiphytes as reservoirs of fungal biodiversity; Schizophyllum commune, Stagonosporopsis cucurbitacearum, Xylaria adscendens, Fusarium...
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