Posted by admin on Nov 30, 2021 in |
Oral ulcers have been a source of diagnostic difficulty. This has been due to the overlap in their clinical appearances. The problem is complicated because a number of oral ulcers may be superimposed by infections due to their easy access to the oral cavity and the thin nature of the oral mucous membrane is an additional challenge to their diagnosis. While the diagnosis of some types of oral ulcers is done by their association with constitutional signs and symptoms or lesions on the skin and/or mucous membranes in other regions, ulcers that are localized only to the oral cavity may be more difficult to identify. Most oral ulcers are, biopsied because they are less readily recognizable on the basis of their clinical features. The similarity in histologic features due to contamination by the oral liquids and microflora also, on occasion, makes it difficult to distinguish by masking the basic pathology. Proper history taking, including the personal history and a thorough clinical examination, is a must to rule out malignancy....
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Posted by admin on Nov 30, 2021 in |
To predict the cocos anther dehiscence, a novel method was devised to compile the colossal amount of pollen grains. The matured inflorescence enveloped by the spathe was collected and the anther dehiscence were noticed day by day until the shedding of entire pollen. This study was experimented for a period of eight months between (February) 2018 to 2018 (September). After an experimental trails, sieve and a new tool wrist action shaker methods were used to collect the healthy pollen grains. Proximate analysis was determined by food analysis-FSSAI and association of analytical chemicals method. The complete process of anther dehiscence took 12 -18 days and after an experimental trials the high amount of pollen grains were obtained on the twelfth day. During the month of June amount of pollen i.e. 16.21 ± 0.05 g per 100 g of the fresh flower weight was recorded in wrist action shaker whereas 2.36 ± 0.018 g per 100 g of the flower weight found in sieve method. The average dry weight of pollen...
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Posted by admin on Nov 30, 2021 in |
Heavy metal accumulates mostly in the liver and kidney as these organs involved in the detoxification and excretion of foreign materials. In the present study, we explored the effect of Gum Arabic (GA) and Guar Gum (GG) on mercuric chloride (HgCl2) induced hepatorenal toxicity. Twenty-eight adult male albino rats “Sprague Dawely” weighing 250-300 g were divided into four equal groups: the first group served as the negative control group, the second group received intraperitoneal (I.P.) injection with HgCl2, the third group received HgCl2 injection followed by GA and the fourth group received HgCl2 injection followed by GG. HgCl2 injection caused a significant increase in serum total bilirubin, aspartate aminotransferase (ALT), alanine aminotransferase (AST), creatinine, urea, and uric acids compared to control. Moreover, there was a significant reduction in tissue-reduced glutathione (GSH) with a marked increase in the tissue hydroxyproline content and TGF-β% in the liver and kidney. Also, hepatorenal intoxication was confirmed by histopathological examination compared with the control group. Treatment with GA or GG showed significant recovery (p...
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Posted by admin on Nov 30, 2021 in |
Paracetamol, caffeine, phenylephrine, and chlorphenamine maleate are available on the market to treat pains, psychoactive disorders, and bronchopulmonary disorders. The objective was to develop a single HPLC method to determine paracetamol, caffeine, phenylephrine HCl, chlorphenamine maleate, and its impurities in flu cold tablets combination dosage form. No analytical method is available to assess the quality of flu cold tablets’ combination dosage form; hence the present research was taken. The evaluated method was validated with Inert sustain C18 AQ 250 mm x4.6 mm, 3µm column, flow rate of 0.7 mL/min, 220 nm wavelength, 50 µL injection volume, 35 °C column temperature and gradient program run time 160 min and also used the pH 2.5 and 4.0 phosphate buffer. This single method was developed and validated with precision, accuracy, ruggedness, linearity, robustness, and specificity by following ICH and USP validation of compendial procedures. The degradation study was performed at all stress conditions such as water hydrolysis, acid hydrolysis, base hydrolysis, oxidation, thermal and light exposure, the peak purity of each active...
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Posted by admin on Nov 30, 2021 in |
Dental caries is one of the serious bacterial diseases of the oral cavity caused by diverse Streptococcus species. Streptococcus mutans strains displayed remarkable genotypic and phenotypic diversity. Glucosyl transferase genes are recognized as essential enzymes leading to biofilm production, the destruction of the ecosystem of normal bacterial communities, and the development of dental caries. The purpose of this study is to detect S. mutans associated with Dental Caries among adults. In our studies, a total of 50 plaque specimens, 23 from male and 27 from female from dental caries patient’s samples, were collected from dental clinics in Jeddah province. All bacterial isolates were identified by culture on Tryptone Yeast Extract Cystine w/Sucrose (TYCSB), Bile esculin slant agar, and Blood agar (BA) media. The results of the current study revealed that only four (8.0%) bacterial isolates out of 50 plaque specimens were identified as S. mutans. These four bacterial isolates named RHA1, RHA2, RHA3, and RHA4 were identified by biochemical and molecular tests. Partial DNA fragment of Glucosyl transferase (GtfB)...
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