Posted by admin on Apr 30, 2021 in |
Blood parameters (Hb%, TLC, TLC, ESR, PCV, MCV and MCH) of the catfish, Clarias batrachus (Linn.) were investigated, exposed to different concentrations of lead [Group- A (control), (Group- B (0.5ppm), Group- C (1.0ppm) and Group- D (3.0 ppm)] during different time intervals (7, 14, 21 and 28 days). Haemoglobin values fell to the maximum (11.5%) from its control value (13.0%). TEC values were also reduced (2.90×106/Cumm) during the maximum exposure period (28 days) in groups C and D. On the other hand, TLC increased to the maximum (21,900/Cumm) during 28 days exposure period at 3.00 ppm of lead. ESR values also indicated significant increase (3.10mm/h) at 1.00 ppm of lead during 28 days exposure period. PCV decreased to the maximum (29%) at maximum exposure period (28 days) at intermediate concentration (1.00ppm of lead). MCH increased in all treated groups, but a maximum rise of 40.34pg was recorded at 1.00ppm of lead during 28 days exposure period. Maximum reduction in MCV (100.0µ3) was observed after 28 days exposure period at...
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Posted by admin on Apr 30, 2021 in |
Objective: The current study has been conducted to analyze the potential of antioxidant activity found in two species of genus Urtica, i.e., Urtica dioica and Urtica urens. Methodology: The antioxidant analysis was performed on the crude extract of root, stem and leaves of both the plants, employing both non-enzymatic and enzymatic methods. For non-enzymatic antioxidant activity determination, methods such as 2, 2- diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and Ferrous Reducing Antioxidant Power (FRAP) were opted, whereas for enzymatic analysis, the specific activity of catalase and ascorbate peroxidase assay was examined. Results and Conclusion: The antioxidant activity found via DPPH assay in U. urens ranges from 32.72±0.22 μg/ml to 43.06±1.12 μg/ml and in U. dioica it ranges from 14.28±0.22 μg/ml to 30.88±0.278 μg/ml, while by using FRAP assay the antioxidant activity range found to be 10.412±2.235 μg/ml to 14.005±2.55 μg/ml and 1.526±0.146 μg/ml to 8.014±1.38 μg/ml in U. urens and U. dioica, respectively. The specific activity of antioxidant enzymes catalase and ascorbate peroxidase were exhibited in a range of...
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Posted by admin on Apr 30, 2021 in |
Traditional systems of medicine emphasize the importance of life-style, including dietary habits, for maintaining holistic health. Ayurveda recommends the use of fruits and vegetables in our diet for maintaining mental health. Chenopodium album is one such popular green vegetable. This plant is rich in phenolic compounds – compounds that are valued for their antioxidant activity and potential for management of CNS disorders. In this study, n-hexane, chloroform, methanol, and aqueous extracts of C. album leaves were prepared and standardized on the basis of total phenol content, total flavonoid content, and antioxidant potential (DPPH assay). In-vivo antidepressant activity of chloroform and methanol extracts was evaluated using Forced Swim Test (FST) and Open Field Test (OFT) models in mice. The bioactive methanol extract was fractionated into n-hexane, ethylacetate, and remaining aqueous fractions, followed by standardization and in-vivo evaluation of fractions. EAF had highest TPC (121.16 ± 9.31 mg GAE/g), TFC (55.42 ± 8.12 mg QE/g) and antioxidant potential (42.67 ± 2.25 µg/mL). EAF (40 mg/kg) showed significant antidepressant action without impairing...
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Posted by admin on Apr 30, 2021 in |
Globally, a vast number of people are affected by helminth parasites. The emergence of anthelmintic resistance has paved the way for new leads into potential anthelmintic agents, which may be alternatives to already existing ones. The mode of presentation of herbal medicines affects patient compliance. Traditionally, Cinnamomum zeylanicum is used in the management of helminth infestations. This study sought to evaluate the anthelmintic activities of the crude ethanol extracts of Cinnamomum zeylanicum to authenticate its folkloric use and formulate a dosage form of the most efficacious extract. The leaf and bark powder obtained from the ethanol extract was subjected to phytochemical screening. In-vitro experiments were conducted on Pheretima posthuma and Haemonchus contortus using various concentrations of Cinnamomum zeylanicum leaf and bark extracts. Immediate-release tablets were successfully formulated from Cinnamomum zeylanicum bark extract. The formulated tablets passed the uniformity of weight, friability, disintegration, and hardness tests. The tablets were found to contain the right amount of the extract and produced good in-vitro drug release throughout the duration of the study....
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Posted by admin on Apr 30, 2021 in |
The present study aims to reveal the anti-inflammatory activity of the ethanolic plant extracts of Merremia tridentata against murine models. The Wistar Albino rats of mixed sex were induced inflammation via injecting histamine and formalin. The anti-inflammatory effect of Merremia tridetata was compared with the presence of positive control, Indomethacin. The Paw volume of the control group (group I and group II) have revealed the following mean and standard deviation values of 7.91±0.22 ml and 5.66±0.27 ml, respectively. Whereas the minimum and maximum dosages of plant extracts have shown the values 6.1±0.29 (200 mg/kg) and 5.49±0.18 ml. similarly, the histamine and Indomethacin control group I have revealed the following values 7.96±0.2 ml (group I) and 6.02±0.53 ml (group II). Likewise, the minimum and maximum dosage of plant extracts have revealed the maximum anti-inflammatory effect with the following values 6.30±0.60 ml (200 mg/kg) and 6.13±0.47 ml (400mg/kg). Hence, the present study has exerted the potential biological effect of M. tridetata might be useful for the development of alternative medicine for...
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