Posted by admin on Dec 31, 2021 in |
Objective: Mako (Solanum nigrum L.), Black Nightshade in English, belongs to the family Solanaceae is an edible plant. The whole plant is used as a green source of vegetables and berries as a fruit. It is a good source of antioxidant and has potent anti-inflammatory, diuretic, lithotriptic, wound healing properties. Unani scholars have advocated the berries to treat many renal ailments, including renal failure. The aim of this study was to evaluate the nephroprotective activity of the berries of Mako on gentamicin-induced nephrotoxicity in rats to authenticate the traditional claims. Materials and Methods: Wistar rats were divided into eight groups of six animals in each, group I – control, group II toxicant (gentamicin) and III–VIII were high dose (800 mg/Kg) of methanolic extract (ME), low dose (200 mg/Kg) of ME, Petroleum soluble fraction, chloroform soluble fraction, water-soluble fraction and water-insoluble fraction of ME, respectively. Test drugs were administered from day 1 to 8 along with toxicant from day 4 to 8. Results: At the end of the study, blood...
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Posted by admin on Dec 31, 2021 in |
Seaweeds are potential sources of bioactive molecules. They are known to be rich sources of proteins, carbohydrates, lipids, vitamins, minerals, and other secondary metabolites. To evaluate the presence of these compounds in marine macroalgae collected from Veraval coast of Gujarat, present studies was carried out. The methanol extract of six macroalgae species (Ulva lactuca, Ulva faciata, Acanthophora dendroides, Gracilaria corticata, Padina tetrastromatica, and Cystoseira indica) was subjected to LCMS/MS analysis which suggested presence of amino acids, sugar, vitamins and phytohormones in algae extracts. The aminoacids and vitamins present in Ulva lactuca (betaine, L-methionine, L-asparagine), Ulva faciata ( L-arginine, L-proline, L-histidine, L-valine, L-Threonine, Dihydrofolic acid), Acanthophora dendroides (L-glutamic acid, L-alanine, L-serine, L-phenylalanine, L-tyrosine, nicotinic acid), Gracilaria coeticata (L-canavanine, L-isoleucine, and L-cysteine) and Padina tetrastromatica (L-Aspartic acid, L-leucine) can be utilized for the development of dietary supplements and proteinaceous food for domestic animals. The sugar present in Ulva faciata (glucosamine), Acanthophora dedroides (D-xylose, D-mannose, D-fructose), Gracilaria corticata (D-Rhamnose, fucose, D-galactose), Padina tetrastromatica (D-glucuronic acid, D-glucose, D-mannuronic acid), and Cystosera indica (arabinose,...
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Posted by admin on Dec 31, 2021 in |
Tissues can be preserved for centuries under the conditions of extremely cold temperatures along with the neurological functions of the human brain. It is possible with the process of vitrification; here the cells of the brain are cooled to the cryogenic temperature without the formation of ice. Damage caused due to this process is theoretically reversible as like before, but practically, rejuvenation is possible only by the foreseeable technology which is specific. Injury caused to brain because of low or stopping of blood flow which is as a result of complex series of process which takes more than 6min of time to complete the limit of resuscitation technology. Damage of blood vessels occurs first then the brain tissues if the process of rejuvenation occurs for more than 6 min. For permanent death of neurons, many hours are required. The process of cryopreservation provides a chance for resuscitation by having an opportunity between legal death and permanent loss of life in both humans and animals. At appropriate conditions, the time...
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Posted by admin on Dec 31, 2021 in |
SARS-CoV-2 viral cause infection called COVID-19 was initially reported in China has resulted in a pandemic because it has spread in over 210 countries. This review summarized pathophysiology, clinical features, diagnosis, and COVID 19. The spread of SARS-CoV-2 viral infections is a matter of concern because of a mutant variant of virus. The COVID-19 infection is having 14 days incubation period. Fever, sore throat, cough, severe headache, breathlessness, myalgia and weakness are common symptoms observed in patients with COVID-19. Steps of replication of SARS-CoV-2 virus are attachment, penetration, uncoating, replication, assembly and release. Patients’ screening tests are complete blood count, C-reactive protein (CRP) and erythrocyte, sedimentation rate (ESR), D-dimer, serum ferritin, and others. The reverse transcription-polymerase chain reaction (RT-PCR) is the important diagnostic test of molecular genetic assays for detecting viral RNA. In-Patient of COVID 19 CT scan shows ground-glass opacities with or without consolidations in lung regions. In CT scan, standardized assessment scheme is CORAD classification and assessment of lung involvement can be done CT severity score index....
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Posted by admin on Dec 31, 2021 in |
Medical Case taking process in any field of medicine science is considered to be a significant stage for the treatment management of various diseases. Cardio Vascular diseases (CVD) are one of the life-threatening diseases across the globe, and its prognosis entirely depends on the right intuition of the clinicians; cases may account for 31% of deaths worldwide, based on a recent study. Big Data Management and Machine Learning Algorithms have reached paramount Computational Technological advancement over the last decade and capable of drive applications in diverse domains which can assist in the process of selecting proper medicines. The case-taking approach and selection of drugs were significantly correlated, and the skill of the physicians plays a very important role in the entire procedure blended with proper use of Smart Technology, Artificial Intelligence, and Cloud storage of huge volume of patient’s physiological, clinical and pathological data. In this paper, we have made an attempt to build a digital system driven by smart technology to cater to this equation and explore the...
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