Posted by admin on May 31, 2022 in |
An ethnomedicinal exploration of weeds of Jhansi district, located in the state of Uttar Pradesh in India, has been carried out to identify and find out the use of weeds to treat different ailments. Folklore people living in remote areas do not have easy access to hospitals or medical facilities, so they depend on the plants and weeds present in their surroundings to treat various diseases or physical ailments. A survey was made to get the knowledge of medicinal values of weeds in three regions of Jhansi, and it was found that a total of 30 weeds was used at most by folklore people for their treatments. Identified weeds belonging to families Malvaceae, Asteraceae, Solanaceae, Euphorbiaceae, Poaceae, Amaranthaceae, Convolvulaceae, and Ceasalpinaceae, etc. were found to treat various ailments like fever, cough, flu, nausea, skin diseases, body ache, and overall weeds were also known to increase the immunity of the body. Although there is literature known about the uses of weeds or other plants, it is still required more to...
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Posted by admin on Apr 30, 2022 in |
Context: Ayurveda emphasizes applying herbal, metallic, mineral, and herbo-mineral preparations in therapeutics. Trivanga Bhasma (TB) is a potential trimetallic (Tin, Lead & Zinc) compound formulation widely used in routine Ayurvedic practice to treat several chronic ailments. Objective: To elucidate the toxicity profile of TB by oral administration in wistar albino rats to ascertain the safety aspects. Method: TB was administered in possible higher doses such as TED (Therapeutic Equivalent Dose), TED × 2 (2 times the Therapeutic Equivalent Dose), TED × 5 (5 times the Therapeutic Equivalent Dose) and TED × 10 (10 times the Therapeutic Equivalent Dose) for 28 days. The effect was assessed on ponderal changes, biochemical parameters, histopathology, and tissue analysis. Results: Results showed that TB did not induce any toxicity at TED, TED × 2, TED × 5; whereas histopathology and tissue analysis of very higher dose TED × 10 exhibited toxicity in the liver & kidney. Conclusion: The drug, however, at a dose of TEDx10 showed mild undesirable changes in the liver & kidney;...
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Posted by admin on Apr 30, 2022 in |
The presentation of this work aims to update readers on issues associated with coating pan (CPN), having applicability in the pharmaceutical field. The coating process (CPR) is an important pharmaceutical unit operation that finds pertinence in various product areas extending from conventional (immediate) release to modified release. The CPR involves the substrate coating by spraying the coating material in liquid medium onto them, kept in motion using either CPN or fluid bed processor (FBP). The FBP is used preferably for coating of multi-particulates and powders and rarely for tablets, while CPNs are used for coating tablets and capsules, thus are in extensive use. Conventional CPNs and perforated coating pan (PPN) are the major categories of the CPNs. The PPNs are preferred for the products that call for improved drying efficiency where the drying efficiency of the drying air (DA) is highest. The perforated pan system (PPNSY) is used in the coating system based on the aqueous solvent, with preference to that based on the volatile organic solvent (VOS). Comprehensive...
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Posted by admin on Apr 30, 2022 in |
Objectives: Along with increasing availability and utilization of contraception, it is also important to confirm that the effects of contraception use on resumption of fertility after discontinuation and serious adverse effects produced by synthetic steroidal contraceptives remained a major problem. However, current evidence on resumption of fertility after contraception use is inconclusive, and practically fertility after termination of contraception remains a big concern for women who are using contraception. This fear poses a negative impact on utilization and continuation of contraception. Therefore, the development of new fertility regulating drug from medicinal plants is an attractive proposition. So available reports and identifying the associating factors are important for designing a strategy to overcome the problem. Methods: The review is conducted through a systematic literature search of research articles. Few bibliographic databases and libraries: Pub Med/Medline, Global Health Database, Science direct, Embase, the Cochrane Library were used. Results: The review of different database studies that enrolled profiles of various medicinal plants used for contraception was analyzed. Conclusion and Recommendation: Contraceptive use,...
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Posted by admin on Apr 30, 2022 in |
Nanoemulsions have garnered a lot of interest in recent decades as a result of their unique characteristics. These carriers are optically transparent, non-equilibrium, thermodynamically stable dispersion of nano-sized particles. Nanoemulsions possess great potential for pharmaceuticals, cosmetics, and other application areas ranging from the Oil to the food industry. Incorporating nanotechnology into cosmetic formulations is the newest and most cutting-edge technology accessible. With the ability for excellent dispersion of active substances, merging textures, and controlled delivery into the desired layers of skin, nanoemulsions are becoming increasingly popular in skincare products. Advantages of nanoemulsion over cosmetic technologies (such as liposomes, emulsions and microemulsions) include ease of manufacture, adjustable particle sizes, excellent kinetic stability, and low surfactant levels, as well as market benefits like the ability to be manufactured in a variety of forms, such as spray, foam, liquid and cream have accelerated their use. The fundamental objective of this review is to systematically discuss the components, properties, and capabilities of nanoemulsions as final application products for skincare and other cosmeceutical applications as well as...
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