Posted by admin on Jan 31, 2022 in |
The acute and sub-acute toxicity analysis of Siddha preparation MV kashayam was carried out with Wistar rats as per the guidelines 423 and 407of the Organization for Economic Co‐operation and Development (OECD), respectively. In the acute toxicity study, a single dose of MV kashayam (1000 and 2000 mg/kg body weight) was administered orally to the rats and monitored for 14 days. In the sub-acute toxicity study, rats were orally administered with MV kashayam daily for 28 days at doses of 100 and 200 mg/kg body weight. In both the toxicity study, no rats have exhibited clinical signs of toxicity or mortality, and the doses were well tolerated by rats and no significant change in their mean body weight, food and water intake, haematological, biochemical parameters and his to pathological examinations as compared to that of control group rats. The findings suggest that MV kashayam has a wide margin of safety and a negligible amount of toxicity to ensure the safety and potency of the kashayam, which can be recommended...
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Posted by admin on Jan 31, 2022 in |
Rutin or quercetin-3-O-rutinose (C27H30O16) is an essential member of the flavonoid family, a classification of total components of plant phenolic compounds. Rutin is typically located in buck herb seeds. Broccoli fruits, especially citrus fruits, red apples, and berries and drinks such as beer, tea, and coffee. This bioflavonoid is accountable for imparting color and flavor to fruits and vegetables. Rutin is located in many other plants, such as participants of the Fagopyrum genera, F tataricum, usually regarded as tartarine buckwheat, is specifically prosperous in protein. It works as a coloring agent, meal, additive, and used in cosmetics. Also, rutin has a more potent therapeutic effect than other flavonoid derivatives and therefore it is used as a medication to deal with vascular diseases. Several metals such as mercury, aluminum, titanium, vanadium and nickel can be determined spectroscopically by rutin. Rutin incorporates a broad range of pharmacological properties. Traditionally, it is used as anti-microbial, anti-fungal, and anti-allergic agents. However, the contemporary study proved its multi-spectrum pharmacological benefits for treating several chronic...
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Posted by admin on Jan 31, 2022 in |
Flax (Linum usitatissimum) is an annual herb with a huge source of essential fatty acids, amino acids, vitamin E, organic acids, and cyanogenetic glycosides. Flax is primarily observed with antioxidative and cell rejuvenating properties. Due to the major ups and downs of lifestyle, metabolic syndrome is the most common terminology associated with humans. Metabolic syndrome is amplified by unhealthy food consumption, less physical activity, alcohol consumption, smoking, etc. Heart attack, hyperglycemia, insulin resistance, cancer, in-vitro fertility and other hormonal or neuronal problems are the medusa’s snakes of metabolic syndrome. The constantly changing environment, pollution, bad air quality index, greater amount of carbon footprints, and exhaustion of greenhouse gases are the sources of maladies associated with environmental breakdown. Environmental calamities like consumption of non-renewable fossil fuel, pollutions, melting of the ice age are collectively flowed towards metabolic syndrome. After prolonging intake of Flax (seed or oil) it was observed with greater impacts on mitigation of Diabetes mellitus, occurrence of inflammation, ulcer, atherosclerotic plaque, and maintained the normal levels of hormones...
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Posted by admin on Jan 31, 2022 in |
Candida sp. is currently associated with nosocomial infection; in this study, we aimed to determine the persistence of Candida auris on inanimate surfaces. Two test surfaces (latex gloves and disposable gown) were inoculated with two strains of Candida auris (clinical Ca1 and environmental H005913). The initial concentration of the inoculum was 108 UFC / mL, sampling was performed by rubbing a sterile swab over the surface, being sampled every 48 h, the micro organisms recovered by means of MALDI-TOF mass spectrometry were identified. The persistence of C. auris on gloves surface was 624 h equivalent to 26 days and in disposable gown C. auris clinical 528 h 22 days, C. auris ambient 576 h 24 days; With respect to death kinetics, the values obtained on the glove surface are consistent with the death curve, but unlike disposable gowns, the values were not related to the death curves. According to the results obtained, it is important to manage and control Infections associated with health care since C. auris is a...
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Posted by admin on Jan 31, 2022 in |
Recurrent aphthous Stomatitis (RAS) is a painful ulcerous condition that was conservatively treated using topical corticosteroids, immuno-suppressants, thalidomide with some potential risks and reactions. Considering this, herbal extracts are found to be a better alternative with very minimum side effects. Punica granatum (pomegranate) extract is one such flavonoid-containing food supplement with excellent antimicrobial, anti-inflammatory, and antioxidant properties used in preventing and treating RAS. The aim of the study is to assess the efficacy of Punica granatum extract in treating RAS. Materials And Method: Systematic review of randomized, clinical studies were searched using Pubmed, Scopus, Cochrane, Medline, Science direct, Lilacs, and Grey Literature. Research articles were collected using both electronic and manual search methods with a final record of nineteen. Several articles were scrutinized, redundant information was discarded, and based on the study pattern, interventions, outcomes, eight records were taken for consideration. Results: Four studies were refined in the systematic review with randomized, clinical studies meeting all criteria. These three were statistically significant and the other did not clearly state...
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