Posted by admin on Jun 30, 2017 in |
Mucuna pruriens is a climbing legume used in the treatment of various ailments. It is commonly known as Cowitch or velvet bean. Traditionally, it was used in treating male infertility. The main aim of this study was to identify the bioactive materials present in the methanol extract of Mucuna pruriens seeds by Gas Chromatography Mass Spectrometry (GC-MS) technique. The analysis by GC-MS reveals the presence 5 major compounds namely, Pentadecanoic acid, 14-methyl-, methyl ester, Dodecanoic acid, 9,12-Octadecadienoic acid (Z,Z)-, methyl ester, 9,12- Octadecadienoic acid and 2-Myristynoyl-glycinamide. By comparing with the references of earlier studies, it was clear that these major compounds played a major role in its neuroprotective, antioxidant, anti-inflammatory, anticancer, hepatoprotective, and antimicrobial effects. The presence of antioxidants has been linked with neurogenesis in the brain. The presence of these compounds may authenticate the scientific evidences of many of its proposed therapeutic potentiality of the seeds of Mucuna pruriens...
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Posted by admin on May 31, 2017 in |
In recent years there is more research work taken in Marine sources for its pharmaceutically valuable compounds and active medicines for anticancer, anti diabetic, anti oxidant, antimicrobial, and anti-inflammatory. The present study investigated for the medicinal value of red algae Griffithsia pacifica Kylin (GPK) and its alterations in enzymatic activity of STZ induced diabetic rats. The results gave significant increase in hemoglobin and glycosylated hemoglobin along with the reduction in hyperglycemia. Thus the GPK might serve as an effective natural medicine for anti-hyperglycemic effects of diabetic rats and may be promising for development of phyto medicines for...
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Posted by admin on Apr 30, 2017 in |
Natural pigments have great interest with in the market now a day’s particularly microbial pigments. The various microorganisms such as Micrococcus, Bacillus, Rhodotorula, Monascus, Phaffia, Sarcina and Achromobacter have the capability to produce different pigments. These colors have number of beneficial properties like anti-cancerous, immunosuppressive, antibiotic, anti-proliferative, bio-degradability etc. Further, they have broad area of application mainly in food, dairy, printing, textile and pharmaceutical industries etc. Since, the microorganisms are a significant source of carotenoids and major source of naturally occurring pigments. These carotenoids basically protect cells against photo oxidative damage and hence have vital applications in environment, food and nutrition, disease control, and as potent antimicrobial agents. Use of microbial pigments in processed food is another promising area with large economic potential. However, microbial pigments provide challenges due to lower stability, high cost and variation in shades due to changes in pH. Further, it is also essential to have toxicology studies of these microbial pigments before their use as natural colorants in food...
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Posted by admin on Apr 30, 2017 in |
Nature always stands as a golden mark to exemplify the outstanding phenomena of symbiosis. Natural products from plant, animal and minerals have been the basis of the treatment of human disease. Capsicum plants belongs to the family Solanaceae and kingdom Plantae, consist of 27 species, and approximately 3000 varieties. Chili peppers are used worldwide in foods for their pungent flavor, aroma, and to prolong food spoilage. With capsaicin contents ranging from zero to millions of Scoville heat units, the different varieties offer a wide range of options for people all over the world. The aim of present review is to form a short compilation of the pharmacological and toxicological potentials of this multipurpose fruit. Capsicum, has been used as anti-inflammatory, anti-diabetic, anti-cancer, anti-ulcer, anticoagulant, analgesic, anti-arthritis, immuno-modulatory, memory enhancing, pain relief, hypocholesterolaemic, hypolipidemic, hepatoprotective and antimicrobial effects. It also cause irritation to mucous membrane, inflammation and neurotoxicity. It should not be used on open wounds or abrasions, or near the eyes. It has antagonistic effects on of α-adrenergic blockers,...
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Posted by admin on Apr 30, 2017 in |
Microbial resistance to antibiotics is often caused by biofilm formation of the microbial pathogen. One strategy used to combat this recalcitrance mechanism is by using the combination of antimicrobial drugs. Essential oils have evoked interest as sources of natural products and represent an alternative approach in combating microbial pathogen. The aim of the present work was to investigate the possible synergistic activity of Massoia aromatica oil in combination with Cinnamomum burmanii, Ocimum basilicum, Citrus hystrix and Piper betle oils against Candida albicans biofilm. Biofilm formation inhibition assay and biofilmdegradation assay of essential oils were determined using microtiter broth method. The Fractional inhibitory concentration indices (FICI) of essential oils in combinations were calculated from the checkerboard assay. The synergistic activity was found in combination of M. aromatica oil with all the essential oil tested in inhibit the formation of intermediate stage of C. albicans bio-film. The interaction of M. aromatica oil with all the essential oil tested in inhibit the formation of mature stage of C. albicans biofilm were varied...
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