Posted by admin on Dec 25, 2014 in |
Selaginella bryopteris (L.) Bak. usually known as “Sanjeevani’, is a lithophyte with remarkable resurrection capabilities and medicinal properties. It is traditionally used for curing wounds and irregular menstruation, uterine disorders and other internal injuries. It contains a variety of secondary metabolites such as alkaloids, phenol and terpenoids etc due to which it can act as antioxidants, anti-inflammatory, anti-cancer, anti-allergic, antimicrobial, antifungal, antibacterial, antiviral etc. It is also used as a strength tonic to improve fitness and to extend lifespan by the local tribal communities of India. The herbs are extensively exploited and sold throughout the country in different markets. There is an urgent need to aware the scientist, researchers, forest officials and local peoples about its medicinal properties, traditional knowledge, economic potential, endemic nature, horticultural and aesthetic value. Its distribution, medicinal and economic potential, taxonomy, ecology, causes of depletion and conservation strategies discussed in...
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Posted by admin on Dec 25, 2014 in |
Compounds with a 2(H)-1, 4-benzoxazin-3(4H)-one skeleton have attached the attention of phytochemistry researchers since 2, 4-dihydroxy-(2H)-1,4-benzoxazin-3(4H) and 2,4-dihydroxy-7-methoxy-(2H)-1,4-benzoxazin-3(4H)-one were isolated from plants belonging to the Poaceae family. These compounds exihibit interesting properties11 such as phytotoxic, antimicrobial12, antifeedent, antifungal and insecticidal properties. The reaction of CSI with 2-Chlorobenzyl alcohol result in N-chlorosulphonyl derivatives, which show antibacterial potency. Futher, N-chlorosulphonyl derivatives can be easily cyclofunctionalized. This cyclofunctionalization has been exploited in the synthesis of the title compounds (3). Thus, the title compound being oxygen analogues of 1, 3-thiazine derivatives together with N-sulphonamide moiety could be expected to exhibit enhanced...
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Posted by admin on Dec 25, 2014 in |
The main aim of the present study was to synthesize new leads with potential antibacterial and antioxidant activities. As a part of systematic investigation of synthesis and biological activity, some of the new thiazoldinedione compounds 5a-e were prepared and screened for their antibacterial and antioxidant activities. The antibacterial evaluation of newly synthesized compounds was carried out by cup-plate method. Antimicrobial activity results revealed that compound 5a showed promising activity against bacteria Staphylococcus aureus, Klebsiella pneumonia, and Pseudomonas aeruginosa, 5e was found to be more active aganist Proteus vulgaris. The antioxidant activity was performed by using free radical scavenging activity by DPPH (1, 1-diphenyl-2-picryl-hydrazil) assay method and Ferric ion reduction method, ascorbic acid was used as reference standard. All the tested derivatives show antioxidant activity but compound 5c and 5d show promising antioxidant activity concentration at 50μg /ml and can be further studied with modifications. Some novel thiazolidinediones derivatives 5(a–e) were synthesized by reacting hydrazine hydrate in ethanol to form hydrazinecarboxylicacid [4-(2, 4-Dioxo-thiazolidin-5-ylidenemethyl)-phenyl-esterand substituted derivatives were formed by further reaction....
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Posted by admin on Dec 25, 2014 in |
Objective: Pseudomonas aeruginosa has emerged as an important cause of serious wound infection and death in burn patients. There are a limited numbers of antimicrobial agents affecting the bacterium due to its inherent resistance. Kefir is a natural probiotic which contains diverse spectrum of bacteria, yeasts and their metabolites with potential antimicrobial activity. Current study was designed to investigate the antimicrobial activity of Kefir extract against P. aeruginosa (ATCC 27853) as well as burn clinical isolates. Materials and Methods: In this descriptive study, the Kefir fermented in MRS Broth medium for 24 hours (hrs), 48 hrs and 96 hrs and their extract were used for evaluation of antibacterial effect. The antibacterial effect of different kefir extract were compared based on measurement of diameter of inhibition zone in diffusion plate method, and assessment of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The density of bacteria and percentage of organic acids (lactic and acetic acids) were also tested. Kefir gels were prepared by mixing of equal portions of gel...
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Posted by admin on Dec 1, 2014 in |
The synthesis of nanoparticles has become the matter of great interest in recent times due to its various advantageous properties and applications in various fields. Though physical and chemical methods are more popular for nanoparticle synthesis, the biogenic production is a better option due to eco-friendliness. Morinda coreia leaf ethanol extracts was screened for the synthesis of Silver nanoparticle using 0.1mM concentration of silver nitrate. The peak of 482 nm in UV-Vis Spectroscopy confirmed the presence of silver nanoparticle synthesis. Biosynthesized silver nanoparticles characterized by Scanning Electron Microscope (SEM), Fourier Transform Infra Red Spectroscopy (FT-IR) and Energy-dispersive X-ray spectroscopy (EDX). The silver nanoparticles around 90 nm were formed. Biologically synthesized silver nanoparticles were further examined for antimicrobial activity against both Gram-negative and Gram-positive bacteria. It was observed that a clear zone of growth inhibition was against in E. coli, Vibrio cholerae, Staphylococcus aureus, Bacillus sps, Pseudomonas aeruginosa, Klebsiella pneumoniae, Serratia marcescens, Proteus vulgaris, Staphylococcus mutans and Salmonella typhi confirms the antibacterial property of biologically synthesized...
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